[1]连琯,史晓伟,裴文丽,等.基于数据挖掘的亚急性甲状腺炎中医用药规律分析[J].西部中医药,2019,32(07):69-75.
　LIAN Guan,SHI Xiaowei,et al.TCM Medication Rules Analysis for Subacute Thyroiditis Based on Data Mining[J].Western Journal of Traditional Chinese Medicine,2019,32(07):69-75.
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基于数据挖掘的亚急性甲状腺炎中医用药规律分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年07期
页码:
69-75
栏目:
出版日期:
2019-07-15

文章信息/Info

Title:
TCM Medication Rules Analysis for Subacute Thyroiditis Based on Data Mining
文章编号:
1004-6852(2019)07-0069-07
作者:
连琯1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，史晓伟1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，裴文丽1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，朱文远3，张定华1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2△
1 甘肃省中医院，甘肃 兰州 730050； 2 甘肃中医药大学第一附属医院； 3甘肃中医药大学
Author(s):
LIAN Guan1, 2' target="_blank" rel="external"> 2' target="_blank" rel="external"> 2' target="_blank" rel="external"> 2, SHI Xiaowei1, 2' target="_blank" rel="external"> 2' target="_blank" rel="external"> 2' target="_blank" rel="external"> 2, PEI Wenli1, 2' target="_blank" rel="external"> 2' target="_blank" rel="external"> 2' target="_blank" rel="external"> 2, ZHU Wenyuan3, ZHANG Dinghua1, 2' target="_blank" rel="external"> 2' target="_blank" rel="external"> 2' target="_blank" rel="external"> 2△
1 Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China;2 The First Affiliated Hospital of Gansu University of Chinese Medicine; 3 Gansu University of Chinese Medicine
关键词:
亚急性甲状腺炎; 中医药; 用药规律
Keywords:
subacute thyroiditis;  TCM;  medication rules
分类号:
R287
文献标志码:
A
摘要:
目的：基于数据挖掘方法分析亚急性甲状腺炎（亚甲炎）的中医用药规律。方法：以“亚急性甲状腺炎”和“经验”为关键词，检索时间设定为“2009-03-01”至“2019-03-01”，通过“中国知网”“万方”“维普”等数据库检索，从对亚甲炎的病机认识、治则治法，遣方用药等方面系统整理总结近10年我国中医专家治疗亚急性甲状腺炎的经验。结果：42位专家辨证亚甲炎的病因病机包括外感邪气(24人)、血瘀(19人)，肝郁气滞(19人)，痰热(18人)、痰凝(17人)、热毒壅盛(16人)、正虚(11人)、肝郁化火(9人)，邪郁少阳(3人)、营卫失和(3人)、肝胃郁热(1人)、阴虚阳亢(1人)、湿热(1人)、血热互结(1人)；42位专家治疗亚甲炎分别采用了分期辨证论治法(18人)、辨主要病机论治(17人)、辨证分型论治(5人)、辨因论治(1人)和分类辨证论治(1人)；42位专家治疗亚甲炎的198味常用中药频次40～50次的中药为甘草、茯苓和柴胡；30～40次为连翘和夏枯草；20～30次为牡丹皮、金银花、半夏、浙贝母、玄参、赤芍、陈皮、白芍、党参、薄荷、牛蒡子、黄芩、当归、丹参、栀子、桔梗、川芎、白术。结论：专家们普遍认为亚甲炎的病机为肝郁脾虚、风热侵袭、痰热瘀阻，治疗以疏肝健脾、清热化痰、解毒祛瘀、软坚散结为主。
Abstract:
Objective: To analyze TCM medication rules of subacute thyroiditis based on data mining. Methods: By taking "subacute thyroiditis" and "experience" as the key words, the retrieval time was set from "March, 1st, 2009" to "March, 1st, 2019", CNKI, Wanfang, VIP and others were searched to systematically summarize TCM experts's experience of treating subacute thyroiditis in recent ten years from the understanding to the pathogenesis of subacute thyroiditis, therapeutic principles and theraputic methods, the prescriptions and the herbs. Results: The cause and the pathogenesis of subacute thyroiditis differentiated by 42 specialists contained exogenous pathogen (24 persons), blood stasis (19 persons), liver depression and Qi stagnation (19 persons), phlegm-heat (18 persons), phlegm coagulation (17 persons), heat-toxin congestion and excess (16 persons), healthy Qi deficiency (11 persons), liver depression transforming into fire (9 persons), stagnant pathogen of Shaoyang (3 persons), disharmony between Ying Qi and Defensive Qi (3 persons), liver stomach stagnant heat (1 person), Yin deficiency and Yang hyperactivity (1 person), dampness-heat (1 person) and heat mixing with blood (1 person); therapeutic methods of 42 specialists treating subacute thyroiditis were syndrome differentiation and treatment according to staging (18 persons), main pathogenesis differentiation and treatment (17 persons), syndrome differentiation, patterns and treatment (5 persons), causes differentiation and treatment (1 person); among 198 common herbs used by 42 specialists treating subacute thyroiditis, the herbs showing the frequency of 40 to 50 times were Gancao (glycyrrhizae radix et rhizoma), Fuling (poria) and Chaihu (bupleuri radix); the ones in the frequency of 30 to 40 times were Lianqiao(forsythiae fructus) and Xiakucao (prunellae spica); the ones in the frequency of 20 to 30 times were Mudanpi (moutan cortex), Jinyinhua(lonicerae japonicae flos), Banxia (pinelliae rhizoma), Zhebeimu (fritillaria thunbergii bulbus), Xuanshen (scrophulariae radix), Chishao (paeoniaeradix rubra), Chenpi (citri reticulatae pericarpium), Baishao (paeoniae radix alba), Dangshen(codonopsis radix), Bohe (menthae haplocalycis herba), Niubangzi (arctii fructus), Huangqin (scutellariae radix), Danggui(angelicae sinensis radix), Danshen (salviae miltiorrhizae radix et rhizoma), Zhizi (gardeniae fructus), Jiegeng (platycodonis radix), Chuanxiong (chuanxiong rhizoma) and Baizhu(atractylodis macrocephalae rhizoma). Conclusion: The specialists think that the pathogenesis of subacute thyroiditis are liver depression and spleen deficiency, wind-heat invasion, and phlegm-heat stagnation and obstruction, and the therapies should be soothing liver and invigorating spleen, clearing heat and reducing phlegm, detoxifying and removing stagnation, softening and resolving hard mass mainly.

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备注/Memo

备注/Memo:
收稿日期：2019-04-29*基金项目：甘肃省中医药管理局科研立项课题（编号GZK-2016-37）。作者简介：连琯(1975—)，男，主治医师，研究方向：内分泌疾病的中西医结合防治。△通讯作者：张定华(1964—)，女，主任医师。研究方向：内分泌代谢疾病的中医药防治。
更新日期/Last Update: 2019-07-15