[1]姜敏.自拟黄归汤联合来氟米特对糖尿病肾病患者血清色素上皮源因子水平的影响[J].西部中医药,2020,33(S1):97-98.
 Jinag Min.Effect of self-made Huanggui Decoction combined with leflunomide on serum pigmented epithelial factor level in patients with diabetic nephropathy[J].Western Journal of Traditional Chinese Medicine,2020,33(S1):97-98.
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自拟黄归汤联合来氟米特对糖尿病肾病患者血清色素上皮源因子水平的影响()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
33
期数:
2020年S1
页码:
97-98
栏目:
出版日期:
2025-06-30

文章信息/Info

Title:
Effect of self-made Huanggui Decoction combined with leflunomide on serum pigmented epithelial factor level in patients with diabetic nephropathy
作者:
姜敏
武威市人民医院肾内科 甘肃 武威 733000
Author(s):
Jinag Min
Wuwei,Wuwei 733000,China
关键词:
自拟黄归汤来氟米特糖尿病肾病血清色素上皮源因子水平不良反应
Keywords:
Self-made Huanggui Decoction Leflunomide Diabetic Nephropathy Serum Pigment Epithelial Source Factor Level Adverse Reactions
摘要:
目的 探讨自拟黄归汤联合来氟米特对糖尿病肾病患者血清色素上皮源因子水平的影响。方法 选取2017年3月-2018年3月我院收治的132例糖尿病肾病患者,随机分为三组,对照1组应用自拟黄归汤治疗,对照2组应用来氟米特治疗,研究组应用自拟黄归汤联合来氟米特治疗,并对三组患者进行护理干预。比较三组患者治疗效果、不良反应发生率、指标改善情况、肾功和炎性因子指标。结果研究组不良反应发生率低于对照组1组和对照2组(P<0.05);研究组指标改善情况好于对照组1组和对照2组(P<0.05);治疗后,研究组肾功能优于对照组1组和对照2组(P<0.05);研究组炎性因子指标好于对照1组和对照2组(P<0.05);研究组治疗效果好于对照1组和对照2组(P<0.05)。结论 对糖尿病肾病患者,进行自拟黄归汤联合来氟米特治疗,治疗效果理想,降低了患者血清色素上皮源因子水平和不良反应发生率,改善了患者病情。因此,自拟黄归汤联合来氟米特在糖尿病肾病临床治疗中应进一步推广和应用。
Abstract:
Objective To investigate the effect of self-made Huanggui Decoction combined with leflunomide on serum levels of pigmented epithelial factor in patients with diabetic nephropathy. Methods 132 patients with diabetic nephropathy admitted to our hospital from March 2017 to March 2018 were randomly divided into three groups. The control group was treated with self-made Huanggui Decoction and the control group was treated with leflunomide. The study group was treated with self-made Huanggui decoction combined with leflunomide. Nursing intervention was given to the three groups. The therapeutic effect, incidence of adverse reactions, improvement of indicators, renal function and inflammatory factors were compared among the three groups. Results The incidence of adverse reactions in the study group was lower than that in the control group 1 and 2 (P < 0.05); the improvement of indicators in the study group was better than that in the control group 1 and 2 (P < 0.05); after treatment, the renal function in the study group was better than that in the control group 1 and 2 (P < 0.05); the inflammatory factors in the study group were better than those in the control group 1 and 2 (P < 0.05); and the therapeutic effect in the study group was better than that in the control group 1 and 2 (P < 0.05 Group A and control group 2 (P < 0.05). Conclusion For patients with diabetic nephropathy, self-made Huanggui Decoction combined with leflunomide is effective, reducing the level of serum pigmented epithelial factor and the incidence of adverse reactions, and improving the patient’s condition. Therefore, self-made Huanggui Decoction combined with leflunomide should be further promoted and applied in the clinical treatment of diabetic nephropathy.

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备注/Memo

备注/Memo:
收稿日期: 2020-08-12作者简介: 姜敏 (1983—), 女, 硕士, 主治医师。研究方向: 肾脏疾病。
更新日期/Last Update: 2021-03-01