[1]韩庭伟,武占玮.芪苈强心胶囊联合曲美他嗪治疗气虚血瘀型慢性肺源性心脏病60例[J].西部中医药,2019,32(08):95-97.
 HAN Tingwei,WU Zhanwei.Qili Qiangxin Capsules Combined with Trimetazidine in the Treatment for 60 Cases of Chronic Pulmonary Heart Disease of Qi Deficiency and Blood Stasis Pattern[J].Western Journal of Traditional Chinese Medicine,2019,32(08):95-97.
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芪苈强心胶囊联合曲美他嗪治疗气虚血瘀型慢性肺源性心脏病60例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年08期
页码:
95-97
栏目:
出版日期:
2019-08-15

文章信息/Info

Title:
Qili Qiangxin Capsules Combined with Trimetazidine in the Treatment for 60 Cases of Chronic Pulmonary Heart Disease of Qi Deficiency and Blood Stasis Pattern
文章编号:
1004-6852(2019)08-0095-03
作者:
韩庭伟1武占玮2
1 临夏州中医医院,甘肃 临夏 731100; 2 古浪县干城乡武占玮诊所
Author(s):
HAN Tingwei1, WU Zhanwei2
1 Linxia Hui Autonomous Prefecture TCM Hospital, Linxia 731100, China2 Gancheng Township Wu Zhanwei Clinic
关键词:
心脏病肺源性慢性气虚血瘀芪苈强心胶囊参附注射剂曲美他嗪
Keywords:
heart disease pulmonary chronic Qi deficiency and blood stasis pattern Qili Qiangxin capsules
分类号:
R541.2
文献标志码:
B
摘要:
目的:观察芪苈强心胶囊联合曲美他嗪治疗气虚血瘀型慢性肺源性心脏病的临床疗效。方法:将120例患者随机分为观察组和对照组,每组60例。2组均给予抗感染、祛痰平喘药物治疗,对照组同时服用盐酸曲美他嗪胶囊,20 mg/次,3次/d。观察组在对照组治疗的基础上服用芪苈强心胶囊,4粒/次,3次/d。2组均连续治疗4周。观察2组临床疗效,比较2组治疗前后症状积分及第1秒用力呼气容积/用力肺活量比值(FEV1/FVC)、最大呼气中段流速(MMEF)、神经末端脑钠肽前体(NT-proBNP)水平变化情况。结果:总有效率观察组为95.0%,对照组为80.0%,2组比较差异有统计学意义(P<0.05)。紫绀、心悸、胸闷、喘息、咳嗽、咯痰等症状积分治疗前后2组组内比较,差异有统计学意义(P<0.05);治疗后2组组间比较差异有统计学意义(P<0.05)。FEV1/FVC、MMEF及NT-proBNP值治疗前后2组组内比较,差异有统计学意义(P<0.05);治疗后2组组间比较差异有统计学意义(P<0.05)。结论:芪苈强心胶囊联合曲美他嗪治疗气虚血瘀型慢性肺源性心脏病具有较好的临床疗效,可有效改善临床症状,提高心肺功能。
Abstract:
Objective: To survey clinical effects of Qili Qiangxin capsules combined with trimetazidine in treating chronic pulmonary heart disease of Qi deficiency and blood stasis pattern. Methods: All 120 patients were randomized into the observation group and the control group, 60 cases each group. Both groups were given conventional antibiotics to fight againt infection and the medicine to eliminate phlegm and relieve the asthma, the control group took trimetazidine capsules, 20 mg each time, three times each day. The observation group took Qili Qiangxin capsules, four pills each time, three times each day. Both groups were treated for four weeks consecutively. To observe clinical effects of both groups, to compare symptom scores, forced exhalation volume in the first second/forced vital capacity (FEV1/FVC), the levels of MMEF and NT-proBNP before and after treating between both groups. Results: Total effective rates of the observation group and the control group were 95.0% and 80.0%, and the difference had statistical meaning (P<0.05). The difference was statistically significant in the scores of the symptom including cyanosis, palpitation, chest stuffiness, panting, cough, coughing up sputumn and others within two groups before and after treating (P<0.05); the difference was statistically significant between both groups after treatng (P<0.05). There was a significant difference in FEV1/FVC, MMEF and NT-proBNP within two groups before and after treating (P<0.05); the difference showed statistical meaning between both groups after treating (P<0.05). Conclusion: Qili Qiangxin capsules combined with trimetazidine in treating chronic pulmonary heart disease of Qi deficiency and blood stasis pattern could possess better clinical effects, it could improve clinical symptoms and raise cardio-pulmonary function.

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备注/Memo

备注/Memo:
收稿日期:2019-02-27作者简介:韩庭伟(1965—),男,副主任医师。研究方向:慢性肺源性心脏病的诊治。
更新日期/Last Update: 2019-08-15