[1]朱宏华,沈毅韵.清肺通络方口服序贯治疗儿童肺炎支原体肺炎30例[J].西部中医药,2020,33(02):85-88.[doi:10.12174/j.issn.1004-6852.2020.02.24]
　ZHU Honghua,SHEN Yiyun.Oral Sequential Qingfei Tongluo Prescription in Treating 30 Cases of Mycoplasmal Pneumoniae Pneumonia[J].Western Journal of Traditional Chinese Medicine,2020,33(02):85-88.[doi:10.12174/j.issn.1004-6852.2020.02.24]
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清肺通络方口服序贯治疗儿童肺炎支原体肺炎30例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
33
期数:
2020年02期
页码:
85-88
栏目:
出版日期:
2020-02-15

文章信息/Info

Title:
Oral Sequential Qingfei Tongluo Prescription in Treating 30 Cases of Mycoplasmal Pneumoniae Pneumonia
文章编号:
1004-6852(2020)02-0085-04
作者:
朱宏华，沈毅韵
上海中医药大学附属第七人民医院，上海 200137
Author(s):
ZHU Honghua, SHEN Yiyun△
Seventh People′s Hospital of Shanghai University of TCM, Shanghai 200137, China
关键词:
肺炎支原体肺炎; 阿奇霉素; 清肺通络方; 胸片; 小儿
Keywords:
mycoplasmal pneumonia;  azithromycin;  Qingfei Tongluo prescription;  chest film;  children
分类号:
R375.2
DOI:
10.12174/j.issn.1004-6852.2020.02.24
摘要:
目的：观察清肺通络方口服序贯治疗儿童肺炎支原体肺炎(mycoplasma pneumoniae pneumonia,MPP)的临床疗效。方法：将60例患儿随机分为观察组与对照组各30例，2组均先以阿奇霉素静滴治疗5天，观察组第6天起以清肺通络方口服治疗15天，对照组停药3天后，第9天以阿奇霉素口服治疗5天，停药4天后，再口服3天，2组均至第20天治疗完毕后停药。观察临床疗效，比较2组治疗前后中医证候积分、血清支原体抗体IgM(mycoplasma pneumoniae IgM，MP-IgM)转阴率、胸片改变情况及不良反应。结果：总有效率观察组为90.00%(27/30)，对照组为93.33%(28/30)，2组比较差异无统计学意义(P＞0.05)。MP-IgM阴性转化率观察组为50.00%(15/30)，对照组为80.00%(18/30)，2组比较差异有统计学意义(P＜0.05)。主要证候积分、次要证候积分及总积分治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较差异也有统计学意义(P＜0.05)。结论：清肺通络方口服序贯治疗儿童MPP具有良好的疗效，总体与阿奇霉素相当。
Abstract:
Objective: To observe clinical effects of oral sequential Qingfei Tongluo prescription in the treatment for mycoplasma pneumoniae pneumonia (MMP) in children. Methods: Sixty children were randomized into the observation group and the control group, 30 cases each group, both groups were treated by intravenous dripping of azithromycin for five days, the observation group took Qingfei Tongluo prescription orally since the sixth day for 15 days, after withdrew for three days, the control group took azithromycin since the ninth day for five days, continuing taking for three days after stopped for four days, both groups withdrew the drugs till the 20th day. To observe clinical effects, and compare TCM syndrome integrals, serum mycoplasma pneumoniae - IgM (MP - IgM) negative - conversion rate, the changes of chest film and side effects before and after treating. Results: Total effective rate of the observation group was 90.00%(27/30), lower than 93.33%(28/30) of the control group, and the diffference showed no statistical meaning between both groups (P＞0.05). MP - IgM negative - conversion rate of the observation group was 50.00%(15/30), lower than 80.00%(18/30) of the control group, and the difference had statistical meaning between both groups (P＜0.05). The difference presented statistical meaning in main syndrome integrals, secondary syndrome integrals and total integrals within two groups before and after treating (P＜0.05); the difference had statistical meaning between both groups after treating (P＜0.05). Conclusion: Oral sequential Qingfei Tongluo prescription in the treatment for MMP in children could obtain good effects, amounting to azithromycin generally.

相似文献/References:

[1]常建华.中药联合阿奇霉素治疗急性肠炎48例[J].西部中医药,2013,26(09):88.
　CHANG Jianhua.Herbs and Azithromycin Injection for 48 Cases of Acute Enteritis[J].Western Journal of Traditional Chinese Medicine,2013,26(02):88.
[2]韩建东.中药联合阿奇霉素治疗小儿支原体肺炎的疗效及对血清炎性因子的影响[J].西部中医药,2015,28(03):121.

备注/Memo

备注/Memo:
收稿日期：2019-04-21*基金项目：上海市卫计委中发办中西医结合儿科重点专科建设浦东新区中医学科建设三年行动计划建设项目（PDZY-2018-0609）。作者简介：朱宏华(1974—)，男，主治医师。研究方向：儿科影像学。通讯作者：沈毅韵(1982—)，女，博士学位，主治医师。研究方向：小儿呼吸系统疾病的中西医结合防治。
更新日期/Last Update: 2020-02-15