[1]蒋锐沅,荣震,满婷婷,等.原发性肝癌中医证型与组织学分型及形态学分型的相关性研究[J].西部中医药,2021,34(10):99-102.[doi:10.12174/j.issn.2096-9600.2021.10.24]
　JIANG Ruiyuan,RONG Zhen,MAN Tingting,et al.Study on the Correlation between TCM Patterns, Histological and Morphological Types of Primary Liver Cancer[J].Western Journal of Traditional Chinese Medicine,2021,34(10):99-102.[doi:10.12174/j.issn.2096-9600.2021.10.24]
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原发性肝癌中医证型与组织学分型及形态学分型的相关性研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年10期
页码:
99-102
栏目:
调查分析
出版日期:
2021-10-15

文章信息/Info

Title:
Study on the Correlation between TCM Patterns, Histological and Morphological Types of Primary Liver Cancer
作者:
蒋锐沅1, 荣震2, 满婷婷1, 覃艳春1, 莫春梅2
1.广西中医药大学研究生院，广西 南宁 530000
2.深圳市宝安纯中医治疗医院
Author(s):
JIANG Ruiyuan1, RONG Zhen2, MAN Tingting1, QIN Yanchun1, MO Chunmei2
1.Graduate School, Guangxi University of Chinese Medicine, Nanning 530000, China
2.Shenzhen City Baoan TCM Hospital
关键词:
肝癌; 原发性; 中医证型; 组织学; 形态学
Keywords:
primary liver cancer; TCM patterns; histology; morphology
分类号:
R735
DOI:
10.12174/j.issn.2096-9600.2021.10.24
摘要:
目的探究原发性肝癌（primary liver cancer，PLC）常见中医证型与组织学分型、形态学分型之间存在的相关性。 方法选择确诊为原发性肝癌的372名患者，按照中医病证分型，将患者分为肝郁脾虚证、肝热血瘀证、肝胆湿热证、肝肾阴虚证4型。分析不同组织学分型、形态学分型肝癌患者的中医证候分布情况，探求其中的相关性。 结果肝郁脾虚证152例（40.86%）；肝胆湿热证69例（18.55%），肝热血瘀证72例（19.35%），肝肾阴虚证79例（21.24%）。肝细胞癌284例，以肝郁脾虚证最为常见；胆管细胞癌45例，以肝胆湿热证最为常见；混合型肝癌24例，以肝热血瘀证最为常见；其他组织学分型14例，以肝肾阴虚最为常见。弥散型肝癌97例，以肝郁脾虚证最为常见；结节型肝癌123例，以肝郁脾虚证最为常见；块状型肝癌84例，以肝热血瘀证最为常见；小癌型68例，以肝肾阴虚最为常见。 结论原发性肝癌患者的不同组织学分型、形态学分型与中医证型存在一定的相关性，对PLC的辨证分型存在一定的指导意义，也对PLC的流行病学调查研究提供一定的参考意义。
Abstract:
ObjectiveTo discuss the connections between common TCM patterns, histological and morpho-logical patterns of PLC. MethodsAll 372 patients diagnosed as PLC were chosen and divided into liver depression and spleen deficiency pattern, liver heat blood stasis pattern, liver-gallbladder damp-heat pattern, liver-kidney Yin deficienciy pattern according to the classifications of TCM patterns. To analyze the distribution conditions of TCM patterns of the patients of different morphological and histological patterns, and survey their connections. ResultsThere were 152 cases of liver depression and spleen deficiency pattern (40.86%); 69 cases of liver-gallbladder damp-heat pattern (18.55%); 72 cases of liver heat blood stasis pattern (19.35%); and 79 cases of liver-kidney Yin deficienciy pattern (21.24%). Mostly 284 cases of hepatocellular carcinoma were of liver depression and spleen deficiency pattern; 45 cases of cholangiocarcinoma of liver-gallbladder damp-heat pattern; 24 cases of mixed hepatocellular carcinoma of liver heat blood stasis pattern; 14 cases of other histological patterns of liver-kidney Yin deficienciy pattern. Liver depression and spleen deficiency pattern is the most common type among 97 cases of diffuse liver cancer; liver depression and spleen deficiency pattern is the most common type among 123 cases of nodular liver cancer; liver heat blood stasis pattern is the most common type among 84 cases of massive hepatocellular carcinoma; liver-kidney Yin deficienciy pattern is the most common type among 68 cases of small cancer type. ConclusionThere is a certain correlation between different histological and morphological patterns, TCM patterns of PLC, which could guide syndrome differentiation and patterns of TCM, and provide the reference for the study on epidemiological investigation of PLC.

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备注/Memo

备注/Memo:
蒋锐沅（1994—），男，在读硕士研究生，医师。研究方向：恶性肿瘤的中医药防治。国家自然科学基金（81660774，81760850）；国家传染病防治重大专项课题（2018ZX1030350-001，2018ZX10303502-002）。
更新日期/Last Update: 2021-10-15