中药足浴联合地屈孕酮对胎动不安患者焦虑情绪及睡眠质量的影响-《西部中医药》

文章信息/Info

Title:: Influence of Herbal Foot Bath and Didroxyprogesterone on Anxiety and Quality of Sleep in Patients Suffering Fetal Agitation

Author(s):: HU Shuling, ZHOU Yi, TIAN Dan; Department of Gynecology and Obstetrics, Hainan Provincial Hospital of Traditional Chinese Medicine, Haikou 570203, China

Keywords:: FA; anxiety; quality of sleep; herbal foot bath; didroxyprogesterone

摘要:: 目的探讨中药足浴联合地屈孕酮对胎动不安（fetal agitation，FA）患者焦虑情绪及睡眠质量的影响。方法将FA患者123例按随机数字表法分为A组62例、B组61例，A组予中药足浴联合地屈孕酮治疗，B组予地屈孕酮治疗。比较两组患者血清β-人绒毛膜促性腺激素（β-human chorionic gonadotropin，β-HCG）、孕酮（progesterone，P）、雌二醇（estradiol，E₂）和糖类抗原125（carbohydrate antigen 125，CA125）等水平；采用焦虑自评量表（self-rating anxiety scale，SAS）评价两组患者治疗前后焦虑情绪改善情况；采用匹兹堡睡眠质量指数量表（Pittsburgh sleep quality index，PSQI）评价患者睡眠质量；观察治疗前后患者中医证候评分变化情况及总有效率。结果1）治疗后A组患者β-HCG、P、E₂水平高于B组，CA125水平低于B组（P＜0.05）；2）治疗后A组SAS及PSQI评分均低于B组（P＜0.05）；3）治疗后A组中医证候评分低于B组（P＜0.05）；4）A组总有效率高于B组（P＜0.05）。结论中药足浴联合地屈孕酮能有效改善FA患者焦虑情绪及患者睡眠质量，效果优于单用地屈孕酮治疗。

Abstract:: ObjectiveTo explore the effects of herbal foot bath and didroxyprogesterone on anxieity and quality of sleep in FA patients. MethodsAll 123 patients were divided into 62 cases in group A and 61 cases in group B according to random number table method, group A was treated with herbal foot bath and didroxyprogesterone, and group B with didroxyprogesterone. To compare the levels of β-HCG, P, E₂ and CA125 between both groups, SAS was used to assess the improvements of anxiety before and after treatement; PSQI was applied to assess the quality of sleep of the patients; to observe TCM syndrome scores and total effective rate of the patients before and after treatment. Results1)After treatment, the levels of β-HCG, P and E₂ in group A were higher than these in group B, the levels of CA125 lower than these in group B (P<0.05). 2) After treatment, SAS scores and PSQI scores of group A were lower than these of group B (P<0.05). 3) After treatment, TCM syndrome scores of group A were lower than these of group B (P<0.05). 4) Total effective rate of group A was higher than that of group B (P<0.05). ConclusionHerbal foot bath and didroxyprogesterone could effectively improve anxieity and quality of sleep in FA patients, and its effects better than these of single use of didroxyprogesterone.