[1]张中斌,张玉,李华,等.附桂骨痛胶囊联合腓骨截骨术治疗骨性关节炎效果观察[J].西部中医药,2022,35(03):112-115.[doi:10.12174/j.issn.2096-9600.2022.03.25]
　ZHANG Zhongbin,ZHANG Yu,LI Hua,et al.Observation on Treating Knee Osteoarthritis by Fugui Gutong Capsules and Fibular Osteotomy[J].Western Journal of Traditional Chinese Medicine,2022,35(03):112-115.[doi:10.12174/j.issn.2096-9600.2022.03.25]
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附桂骨痛胶囊联合腓骨截骨术治疗骨性关节炎效果观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年03期
页码:
112-115
栏目:
衷中参西
出版日期:
2022-03-15

文章信息/Info

Title:
Observation on Treating Knee Osteoarthritis by Fugui Gutong Capsules and Fibular Osteotomy
作者:
张中斌, 张玉, 李华, 孙士杰, 郑颖坤
河北省老年病医院骨一科，河北 石家庄 050011
Author(s):
ZHANG Zhongbin, ZHANG Yu, LI Hua, SUN Shijie, ZHENG Yingkun
First Orthopedic Department, Hebei Province Geriatric Hospital, Shijiazhuang 050011, China
关键词:
骨性关节炎; 腓骨截骨术; 膝关节功能; 安全性; 附桂骨痛胶囊
Keywords:
osteoarthritis; fibular osteotomy; knee joint function; safety; capsules
分类号:
R684
DOI:
10.12174/j.issn.2096-9600.2022.03.25
文献标志码:
B
摘要:
目的观察附桂骨痛胶囊联合腓骨截骨术治疗骨性关节炎的有效性与安全性。 方法将膝关节骨性关节炎患者80例，根据随机数字表法分为对照组与观察组各40例，两组患者均接受腓骨截骨术治疗，观察组在此基础上联合附桂骨痛胶囊，连续用药4周，术后随访12周。观察两组临床疗效与不良反应发生情况；使用视觉模拟评分法（visual analogue scale，VAS）评价患者膝关节疼痛缓解情况；观察患者膝关节功能改善情况及膝关节液炎症因子水平变化情况。 结果观察组总有效率为95.00%（38/40），高于对照组的80.00%（32/40），差异有统计学意义（P＜0.05）；术后1周、4周，观察组VAS评分较对照组降低，差异有统计学意义（P＜0.05）；观察组术后4周、12周膝关节功能改善优于对照组，膝关节液炎症因子水平较对照组降低，差异有统计学意义（P＜0.05）；治疗期间两组未见明显不良反应。 结论骨性关节炎患者在接受腓骨截骨术治疗基础上联合使用附桂骨痛胶囊疗效优于单用腓骨截骨术，患者疼痛感及炎症反应更轻，膝关节功能改善更理想，而且无明显不良反应，安全可靠。
Abstract:
ObjectiveTo observe the safety and the effectiveness of Fugui Gutong capsules and fibular osteotomy in the treatment of knee osteoarthritis (KOA). MethodsEighty patients were divided into the control group and the observation group according to random number table method, with 40 cases in each group, both groups accepted fibular osteotomy, and the observation group took Fugui Gutong capsules based on the surgery, they were medicated for four consecutive weeks and followed for 12 weeks after the surgery. To observe clinical effects and the incidence of adverse reaction between both groups; to assess pain remission conditions of knee joints by using VAS, and to observe the improvements of knee joint function and the levels of inflammatory factors in knee joint fluid. ResultsTotal effective rate of the observation group was 95.00%(38/40), higher than 80.00%(32/40) of the control group, and the difference had statistical meaning (P<0.05); VAS scores of the observation group were lower than these of the control group one week and four weeks after the surgery, and the difference showed statistical meaning (P<0.05); the improvements of knee joint function of the observation group were better than these of the control group four weeks and twelve weeks after the surgery, the levels of inflammatory factors in knee joint fluid decreased than these of the control group, and the difference had statistical meaning (P<0.05); no obvious adverse reaction has been seen in both groups. ConclusionClinical effects of Fugui Gutong capsules and fibular osteotomy, which is safe and reliable, are superior to these of only fibular osteotomy in the treatment for KOA patients, the patients feel less pain and inflammation, knee joint function improves more ideal, and they show no obvious adverse reaction.

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备注/Memo

备注/Memo:
张中斌（1967—），男，副主任医师。研究方向：骨外科学。河北省医学科学研究重点课题计划项目（20180684）。
更新日期/Last Update: 2022-06-24