[1]何金丽,雷作汉,刘国安.基于数据挖掘刘国安教授治疗冠心病临床用药规律[J].西部中医药,2023,36(02):62-65.[doi:10.12174/j.issn.2096-9600.2023.02.14]
 HE Jinli,LEI Zuohan,LIU Guoan.Clinical Medication Rules of Professor Liu Guo′an′s Treatment of Coronary Heart Disease Based on Data Mining[J].Western Journal of Traditional Chinese Medicine,2023,36(02):62-65.[doi:10.12174/j.issn.2096-9600.2023.02.14]
点击复制

基于数据挖掘刘国安教授治疗冠心病临床用药规律
分享到:

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年02期
页码:
62-65
栏目:
出版日期:
2023-02-15

文章信息/Info

Title:
Clinical Medication Rules of Professor Liu Guoans Treatment of Coronary Heart Disease Based on Data Mining
作者:
何金丽, 雷作汉, 刘国安
甘肃省中医院,甘肃 兰州 730050
Author(s):
HE Jinli, LEI Zuohan, LIU Guo′an
Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
冠心病数据挖掘刘国安经验
Keywords:
coronary heart diseasedata miningexperience
分类号:
R541.4
DOI:
10.12174/j.issn.2096-9600.2023.02.14
文献标志码:
A
摘要:
目的分析刘国安教授治疗冠心病的用药规律。 方法收集2020年10月1日至2021年10月1日甘肃省中医院刘国安名中医工作室门诊诊治的114例冠心病患者的病案信息,描述性分析用药频数、性味等用药情况,对高频用药进行聚类分析、因子分析。 结果114首处方共涉及中药72味,频数≥30次的中药有18味,前3味依次为甘草、瓜蒌、薤白。药性多为平、温性,其次为寒性和微寒性。药味多为甘,其次为苦、辛。高频药物因子分析得出4个公因子,主要涉及麦冬、五味子、瓜蒌、薤白、半夏、茯苓、甘草等7味中药。高频药物聚类分析得到6类:第1类为瓜蒌、薤白、桂枝、丹参、枳实;第2类为麦冬、五味子、人参、酸枣仁、石菖蒲、三七粉、水蛭;3类为半夏、茯苓、远志;其余3类为单味药,分别是甘草、山药、川芎。 结论刘国安教授认为冠心病多因气阴两虚,气机不畅,血瘀受阻所致,用药以补气养阴、行气除痹及活血祛瘀为主,体现了寓通于补,通补兼施的治疗思想。
Abstract:
ObjectiveTo analyze medication rules of professor Liu Guoan's treatment of coronary heart disease (CHD). MethodsMedical records information of 114 CHD patients diagnosed and treated in professor Liu Guoan's famous TCM doctor's outpatient of Gansu provincial hospital of TCM were collected between October 1st, 2020 and October 1st, 2021, to carry out descriptive analysis of drug use frequency, nature and property, and to perform cluster analysis and factor analysis of high frequency medicine. ResultsThere are 72 herbs involved in 114 prescriptions, 18 herbs with the frequency≥30 times, the top three herbs are Gancao (Glycyrrhizae radix et Rhizoma), Gualou (Trichosanthis fructus) and Xiebai (Allii macrostemonis bulbus). The nature of the medicine is mild and warm, the next cold and slight cold, the flavor of the drug is sweet mostly, the next bitter and pungent. Four common factors are obtained by factor analysis of high-frequency medicine, mainly including Maidong (Ophiopogonis radix), Wuweizi (Schisandrae chinensis Fructus), Gualou, Xiebai, Banxia (Pinelliae Rhizoma), Fuling (poria) and Gancao. By cluster analysis of high-frequency medicine, six categories contain: the first category including Gualou, Xiebai, Guizhi, Danshen and Zhishi; the second category including Maidong (ophiopogonis radix), Wuweizi (schisandrae chinensis fructus), ginseng, Suanzaoren (ziziphi spinosae semen), Shichangpu (ziziphi spinosae semen), Sanqi (notoginseng radix et rhizoma) powder, Shuizhi (hirudo); the third category involving Banxia, Fuling and Yuanzhi; the remaining three categories belong to single herb, referring to Gancao, Shanyao (dioscoreae rhizoma) and Chuanxiong (Chuanxiong Rhizoma) respectively. ConclusionProfessor Liu Guoan considers that CHD is induced by deficiency of Qi and yin, impeded Qi movement, and obstruction caused by blood stasis, mainly administering the medicine of tonifying Qi and nourishing Yin, promoting Qi circulation to remove arthralgia, activating blood to eliminate the stasis, which embodies his therapeutic thinking of finding dredging in tonifying, both unobstructing and tonifying.

相似文献/References:

[1]马思清 指导:谢春毅.瓜蒌薤白三方防治冠心病的研究现状[J].西部中医药,2012,25(10):118.
 MA Si-qing Director: XIE Chun-yi.Exploration on Three Pieces of GuaLou XieBaiFang in the Prevention of Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2012,25(02):118.
[2]潘雪晖.综合护理干预对冠心病患者不良生活方式的影响[J].西部中医药,2013,26(07):105.
 PAN Xuehui.Impact of Comprehensive Nursing Intervention on Lifestyles of Patients with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(02):105.
[3]袁春玲.家庭病床冠心病护理可行性探讨[J].西部中医药,2012,25(07):109.
 YUAN Chun-ling.Probe into Feasibility of Nursing for Patients with Coronary Heart Disease in Family Practice[J].Western Journal of Traditional Chinese Medicine,2012,25(02):109.
[4]王凯,林文.丹红与丹参酮ⅡA治疗冠心病心绞痛疗效比较[J].西部中医药,2013,26(08):88.
 WANG Kai,LIN Wen.Comparison between DanHong Injection and Tanshinone ⅡA in Treating Angina Pectoris of Patients with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(02):88.
[5]赵云霞,刘正跃.综合护理干预对冠心病患者不良生活方式的影响[J].西部中医药,2012,25(05):105.
 ZHAO Yun-xia,LIU Zheng-yue.Effects of Comprehensive Nursing Intervention on Unhealthy Lifestyle of Patients with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2012,25(02):105.
[6]王瑞福.调脂汤对冠心病PCI术后血液流变学及血脂的影响[J].西部中医药,2013,26(12):71.
 WANG Ruifu.Effects of TiaoZhi Tang on Blood Lipid and Rheology of the Patients with Coronary Heart Disease After PCI[J].Western Journal of Traditional Chinese Medicine,2013,26(02):71.
[7]孙文,谢春毅△.丹红注射液治疗冠心病心绞痛临床观察[J].西部中医药,2014,27(03):5.
 SUN Wen,XIE Chunyi.Clinical Observation on DanHong Injection in Treating Coronary Heart Disease Angina Pectoris[J].Western Journal of Traditional Chinese Medicine,2014,27(02):5.
[8]王贵民,李廷保△.中医药治疗前列腺疾病用药规律的数据挖掘研究[J].西部中医药,2014,27(05):77.
 WANG Guimin,LI Tingbao.Data Mining Research on Medication Rules of TCM Treatment for Prostatic Diseases[J].Western Journal of Traditional Chinese Medicine,2014,27(02):77.
[9]付伟光,齐振勇,李爱军,等.HCY、HS-CRP、LP(a)及 D- 二聚体联合检测在冠心病病程中动态检测意义的研究*[J].西部中医药,2014,27(08):148.
[10]张丽君,赵江花,赵海红,等.心脉疏膏穴位贴敷结合西药治疗冠心病心绞痛 40 例[J].西部中医药,2014,27(09):128.
[11]朱若维,李雪菲,牛露娜,等.基于数据挖掘探讨国医大师治疗胸痹心痛痰瘀互结证用药规律及经验[J].西部中医药,2024,37(03):28.[doi:10.12174/j.issn.2096-9600.2024.03.06]
 ZHU Ruowei,LI Xuefei,NIU Luna,et al.TCM National Master's Medication Rules and Experience of the Treatment of Thoracic Obstruction and Cardiac Pain of Intermingled Phlegm and Blood Stasis Pattern Based on Data Mining[J].Western Journal of Traditional Chinese Medicine,2024,37(02):28.[doi:10.12174/j.issn.2096-9600.2024.03.06]

备注/Memo

备注/Memo:
何金丽(1986—),女,硕士学位,主治医师。研究方向:心血管疾病的中西医结合诊治。兰州市科技局项目(2020-ZD-42)。
更新日期/Last Update: 2023-02-15