[1]王琴,陈子端,陈林伟.基于微量元素探讨气血双补方抗慢性心衰的炮制增效作用[J].西部中医药,2023,36(05):33-35.[doi:10.12174/j.issn.2096-9600.2023.05.06]
　WANG Qin,CHEN Ziduan,CHEN Linwei.The Effects of Qixue Shuangbu Prescription after Processing on Chronic Heart Failure Based on Trace Element Theory[J].Western Journal of Traditional Chinese Medicine,2023,36(05):33-35.[doi:10.12174/j.issn.2096-9600.2023.05.06]
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基于微量元素探讨气血双补方抗慢性心衰的炮制增效作用
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年05期
页码:
33-35
栏目:
出版日期:
2023-05-15

文章信息/Info

Title:
The Effects of Qixue Shuangbu Prescription after Processing on Chronic Heart Failure Based on Trace Element Theory
作者:
王琴, 陈子端, 陈林伟
南京中医药大学泰州附属医院，江苏 泰州 225300
Author(s):
WANG Qin, CHEN Ziduan, CHEN Linwei
Taizhou Hospital Affiliated to Nanjing University of Chinese Medicine, Taizhou 225300, China
关键词:
慢性心衰; 炮制增效; 微量元素; 气血双补方
Keywords:
chronic heart failure; the synergistic effects through processing; trace elements; prescription
分类号:
R283.1
DOI:
10.12174/j.issn.2096-9600.2023.05.06
文献标志码:
A
摘要:
目的基于微量元素探讨气血双补方抗慢性心衰的炮制增效作用。 方法将慢性心衰（Chronic heart failure，CHF）SD模型大鼠随机分为气血双补方生品组和炮制品组，分别灌胃等量复方生品及炮制品水煎液，4周后比较炮制前后两组大鼠血清Mg、Ca、Cr、Mn、Fe、Co、Ni、Cu、Zn、Se、Sr、Mo、F、Ba 14种微量元素含量。 结果灌胃气血双补方不同汤液后两组模型大鼠血清Mg、Ca、Zn、Se元素含量高于灌胃前（P＜0.05），炮制品组Mg、Ca、Mn、Fe、Cu、Zn及Se高于生品组（P＜0.05）。 结论气血双补方炮制后可能通过提高Mg、Ca、Mn、Fe、Cu、Zn及Se元素含量发挥抗CHF的炮制增效作用。
Abstract:
ObjectiveTo discuss the synergistic effects of Qixue Shuangbu prescription through processing on chronic heart failure (CHF) based on trace element theory. MethodsSD rat models with CHF were randomized into the crude drug group of Qixue Shuangbu prescription and processed products group, and they were drenched with the same amount of compound crude drug and the decoction of processed products respectively, to compare the contents of 14 kinds of trace elements including Mg, Ca, Cr, Mn, Fe, Co, Ni, Cu, Zn, Se, Sr, Mo, F and Ba in the rats between both groups after four weeks of treatment. ResultsAfter the gavage, the contents of Mg, Ca, Zn and Se in the rat models of both groups were higher than these before the gavage (P<0.05), the processed products group was higher than the crude drug group in the contents of Mg, Ca, Mn, Fe,Cu, Zn and Se (P<0.05). ConclusionAfter the processing, Qixue Shuangbu prescription might develop its synergistic effects against CHF through processing possibly through raising the contents of Mg, Ca, Mn, Fe, Cu, Zn and Se.

相似文献/References:

[1]李彬,陈静,赵慧辉,等.依据证候要素辨证治疗慢性心衰的成本―效用分析[J].西部中医药,2015,28(09):56.
[2]杨阿妮,柳树英,王煜.王自立主任医师从脾胃论治慢性心衰临床体会[J].西部中医药,2021,34(01):28.[doi:10.12174/j.issn.2096-9600.2021.01.07]
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备注/Memo

备注/Memo:
王琴（1990—），女，硕士学位，主管中药师。研究方向：中药心血管药理学研究。国家自然科学基金（81903802）；泰州市科技支撑计划社会发展项目（TN202112）；泰州市中医药科技发展项目（TZ202115）；泰州市第五期“311工程”科研项目（RCPY202126）；泰州市“凤城英才计划”青年科技人才托举工程。
更新日期/Last Update: 2023-05-15