[1]刘寅,艾春玲,李秀玲,等.中医辨证治疗前庭性偏头痛的多中心前瞻性队列研究[J].西部中医药,2024,37(02):149-152.[doi:10.12174/j.issn.2096-9600.2024.02.29]
　LIU Yin,AI Chunling,LI Xiuling,et al.Syndrome Differentiation and Treatment of Vestibular Migraine: Multi-center Prospective Cohort Study[J].Western Journal of Traditional Chinese Medicine,2024,37(02):149-152.[doi:10.12174/j.issn.2096-9600.2024.02.29]
点击复制

中医辨证治疗前庭性偏头痛的多中心前瞻性队列研究
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年02期
页码:
149-152
栏目:
临床研究
出版日期:
2024-02-15

文章信息/Info

Title:
Syndrome Differentiation and Treatment of Vestibular Migraine: Multi-center Prospective Cohort Study
作者:
刘寅1, 艾春玲1, 李秀玲1, 王彦红2, 刘艳华3, 项颗1, 孙莉1
1.吉林省中医药科学院，吉林 长春 130021
2.长春市中医院，吉林 长春 130052
3.长春市中心医院，吉林 长春 130051
Author(s):
LIU Yin1, AI Chunling1, LI Xiuling1, WANG Yanhong2, LIU Yanhua3, XIANG Ke1, SUN Li1
1.Jilin Academy of Traditional Chinese Medicine, Changchun 130021, China
2.Changchun Hospital of TCM, Changchun 130052, China
3.Changchun Central Hospital, Changchun 130051, China
关键词:
前庭性偏头痛; 中医辨证治疗; 用药规律; 队列研究
Keywords:
vestibular migraine; syndrome differentiation and treatment; the medication rules; cohort study
分类号:
R747.2
DOI:
10.12174/j.issn.2096-9600.2024.02.29
文献标志码:
B
摘要:
目的评价中医辨证治疗前庭性偏头痛的临床疗效，探讨中医辨证用药规律。 方法采用前瞻性队列研究方法，选取前庭性偏头痛患者197例，根据是否采用中医辨证治疗为暴露因素，分为中药组与西药组，分别为123例与74例。观察两组治疗第4、8、12周的眩晕复发率及相关结局指标。 结果治疗第4、8、12周，眩晕复发率中药组依次为14.9%、18.4%、29.7%，西药组依次为12.3%、32.8%、55.6%，其中第8、12周两组比较差异有统计学意义（P＜0.05）；治疗后第4周，眩晕残障量表评分（dizziness handicap inventory，DHI）、VAS评分改善情况西药组优于中药组，但差异无统计学意义（P＞0.05），第8、12周DHI、VAS评分改善情况中药组均优于西药组（P＜0.05）；共收集门诊处方273首，涉及中药76味，使用频率前十位的中药依次为天麻、法半夏、柴胡、茯神、远志、茯苓、酸枣仁、煅龙骨、珍珠母、黄芩。 结论中医辨证治疗前庭性偏头痛在改善眩晕症状，控制眩晕复发方面优势明显，但起效速度方面不及西药治疗。临床用药以疏肝解郁、重镇安神为主，安神之法应贯穿治疗始终。
Abstract:
ObjectiveTo evaluate clinical effects of syndrome differentiation and treatment for vestibular migraine, and to explore the medication rules of TCM syndrome differentiation. MethodsA prospective cohort study of 197 patients with vestibular migraine was conducted, according to whether they accepted TCM syndrome differentiation and treatment as exposure factors, they were allocated to TCM group (123 cases) and Western medicine group (74 cases) respectively. To observe vertigo recurrence rate and the relevant outcome indicators after four, eight and 12 weeks of the treatment between both groups. ResultsAfter four, eight and 12 weeks of the treatment, the relapse rates of vertigo in TCM groups were 14.9%, 18.4% and 29.7%, while these in Western medicine group were 12.3%, 32.8% and 55.6%, and the difference had statistical meaning after eight and 12 weeks of the treatment between both groups (P<0.05); four weeks after the treatment, the improvements of DHI and VAS of the Western medicine group were better than these of TCM group, while the difference had no statistical meaning (P>0.05), the improvements of DHI and VAS of TCM group were superior to these of Western medicine group on the eighth and 12th weeks (P<0.05); all 273 outpatient prescriptions were collected, involving 76 herbs, the top ten traditional Chinese medicine used were Tianma (Gastrodiae rhizoma), Fabanxia (Pinelliae rhizoma praeparatum), Chaihu((Bupleuri radix), Fushen (Poria cum Ligno Hospite), Yuanzhi (Polygalae radix), Fuling (Poria), Suanzaoren (Ziziphi spinosae semen), Duanlonggu (forged fossil fragments), Zhenzhumu (Margaritifera concha) and Huangqin (Scutellariae radix). ConclusionThe advantages of syndrome differentiation and treatment for vestibular migraine are obvious in improving the symptoms of vertigo and controlling the recurrence of vertigo, however, it is slower than the onset of action of Western medicine treatment. Soothing liver and relieving depression, tranquilization with heavy materials could be adopted as the main therapy, and the tranquilizing method should be used throughout the treatment.

备注/Memo

备注/Memo:
刘寅（1986—），男，硕士学位，主治医师。研究方向：眩晕病的中医药防治及研究。吉林省中医药科技项目（2020027）。
更新日期/Last Update: 2024-02-15