[1]江婕妤,王雨莎,廉艺童,等.糖尿病视网膜病变中视网膜色素上皮细胞氧化应激损伤的中医药治疗研究进展[J].西部中医药,2025,38(05):112-117.[doi:10.12174/j.issn.2096-9600.2025.05.21]
　JIANG Jieyu,WANG Yusha,LIAN Yitong,et al.Research Progress of TCM Therapy for Oxidative Stress Injury of Retinal Pigment Epithelium Cells in Diabetic Retinopathy[J].Western Journal of Traditional Chinese Medicine,2025,38(05):112-117.[doi:10.12174/j.issn.2096-9600.2025.05.21]
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糖尿病视网膜病变中视网膜色素上皮细胞氧化应激损伤的中医药治疗研究进展()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年05期
页码:
112-117
栏目:
研究进展
出版日期:
2025-05-15

文章信息/Info

Title:
Research Progress of TCM Therapy for Oxidative Stress Injury of Retinal Pigment Epithelium Cells in Diabetic Retinopathy
作者:
江婕妤1,2, 王雨莎1,2, 廉艺童1,2, 阳承1,2, 刘志敏2, 陈向东2,3,4,5
1.湖南中医药大学，湖南 长沙 410208
2.湖南中医药大学第一附属医院眼科，湖南 长沙 410007
3.湖南省中医药防治眼耳鼻喉疾病与视功能保护工程技术研究中心，湖南 长沙 410208
4.中医药防治眼病与视功能保护湖南省工程研究中心，湖南 长沙 410208
5.中医药防治眼耳鼻喉疾病湖南省重点实验室，湖南 长沙 410007
Author(s):
JIANG Jieyu1,2, WANG Yusha1,2, LIAN Yitong1,2, YANG Cheng1,2, LIU Zhimin2, CHEN Xiangdong2,3,4,5
1.Hunan University of Chinese Medicine, Changsha 410208, China
2.Eye Department, The First Hospital of Hunan University of Chinese Medicine, Changsha 410007, China
3.Hunan Engineering Technology Research Center for the Prevention and Treatment of Otorhinolaryngologic Diseases and Protection of Visual Function with Chinese Medicine, Changsha 410208, China
4.Hunan Engineering Technology Research Center for the Prevention and Treatment of Oculopathy and Protection of Visual Function with Chinese Medicine, Changsha 410208, China
5.Hunan Provincial Key Laboratory of Traditional Chinese Medicine for the Prevention and Treatment of Otorhinolaryngologic Diseases, Changsha 410007, China
关键词:
糖尿病视网膜病变; 视网膜色素上皮细胞; 氧化应激; 中医药; 研究进展
Keywords:
diabetic retinopathy; retinal pigment epithelium; oxidative stress; traditional Chinese Medicine; research progress
分类号:
R255.4
DOI:
10.12174/j.issn.2096-9600.2025.05.21
文献标志码:
A
摘要:
从血-视网膜屏障（blood-retinal barrier，BRB）和视网膜色素上皮（retinal pigment epithelium，RPE）细胞两方面总结了糖尿病视网膜病变（diabetic retinopathy，DR）与RPE细胞的结构与主要功能作用，指出在DR发生发展中，修复BRB外屏障的RPE细胞发挥关键作用。对DR中RPE细胞的作用及氧化应激损伤机制进行综述，阐明了中药单体及其有效提取物、中药复方及中成药对DR的抗氧化治疗作用，以期为DR的临床治疗提供参考。
Abstract:
The structure and main functions of DR and RPE cells were summarized from BRB and RPE cells, it was pointed out that the repair of RPE in the outer barrier of BRB is playing the vital role in the incidence and development of DR. This paper summarizes the role of RPE cells in DR and the mechanism of oxidative stress damage, and expounds the effect of Chinese medicine, including herbal monomer, and its effective extracts, herbal compounds and Chinese patent drug, on DR from the perspective of RPE cell oxidative stress injury, so as to provide the reference for clinical treatment of DR.

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备注/Memo

备注/Memo:
江婕妤（1997—），女，在读博士研究生。研究方向：中医药防治眼底病。国家自然科学基金面上项目（82374525）；湖南省眼科疾病（中医）临床医学研究中心（2023SK4038）；湖南省自然科学基金（2021JJ30520）；湖南省教育厅科学研究项目（19A362，22A0250）；湖南省中医药管理局科研项目（201917）；长沙市科学技术局基金项目（kq2014226）。
更新日期/Last Update: 2025-05-15