[1]刘懿,赵泉霖,孟醒,等.糖尿病肾脏病氧化应激机制与中医药防治的研究进展[J].西部中医药,2025,38(05):118-126.[doi:10.12174/j.issn.2096-9600.2025.05.22]
　LIU Yi,ZHAO Quanlin,MENG Xing,et al.Research Progress of Oxidative Stress Mechanism and TCM Prevention and Treatment of Diabetic Kidney Disease[J].Western Journal of Traditional Chinese Medicine,2025,38(05):118-126.[doi:10.12174/j.issn.2096-9600.2025.05.22]
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糖尿病肾脏病氧化应激机制与中医药防治的研究进展()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年05期
页码:
118-126
栏目:
研究进展
出版日期:
2025-05-15

文章信息/Info

Title:
Research Progress of Oxidative Stress Mechanism and TCM Prevention and Treatment of Diabetic Kidney Disease
作者:
刘懿1, 赵泉霖2, 孟醒1, 安川1
1.山东中医药大学，山东 济南 250355
2.山东中医药大学附属医院，山东 济南 250014
Author(s):
LIU Yi1, ZHAO Quanlin2, MENG Xing1, AN Chuan1
1.Shandong University of Traditional Chinese Medicine, Jinan 250355, China
2.Affiliated Hospital to Shandong University of Traditional Chinese Medicine, Jinan 250014, China
关键词:
糖尿病肾病; 氧化应激; 中医药; 治疗; 研究进展
Keywords:
diabetic kidney disease; oxidative stress; TCM; therapy; research progress
分类号:
R255.4
DOI:
10.12174/j.issn.2096-9600.2025.05.22
文献标志码:
A
摘要:
从肾素-血管紧张素-醛固酮系统、线粒体功能障碍、烟酰胺腺嘌呤二核苷酸磷酸氧化酶、晚期糖基化终末产物、蛋白激酶C、多元醇、己糖胺等途径综述糖尿病肾脏病（diabetic kidney disease，DKD）的氧化应激机制；中医药能够改善氧化应激，延缓DKD进展，保护DKD早期不同个体肾脏功能，调理全身机能，临床疗效明确。
Abstract:
The mechanism of oxidative stress in diabetic kidney disease (DKD) was summarized from renin-angiotensin-aldosterone system, mitochondrial dysfunction, nicotinamide adenine dinucleotide phosphate oxidase, advanced glycosylation end products, protein kinase C, polybasic alcohol and hexosamine; TCM could enhance oxidative stress, delay DKD progression and protect renal functions of different individuals suffering early DKD, as well as adjust the function with clear clinical effects.

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备注/Memo

备注/Memo:
刘懿（1998—），男，在读博士研究生。研究方向：中医药防治内分泌及心血管疾病。国家自然科学基金（81774254）。
更新日期/Last Update: 2025-05-15