[1]李志敏,殷浩辉,郭超峰.基于数据挖掘的中医药治疗梅核气的用药规律分析[J].西部中医药,2025,38(06):106-109.[doi:10.12174/j.issn.2096-9600.2025.06.20]
　LI Zhimin,YIN Haohui,GUO Chaofeng.Data mining-Based Analysis of Medication Rules of TCM Therapy for Globus Hysteriocus[J].Western Journal of Traditional Chinese Medicine,2025,38(06):106-109.[doi:10.12174/j.issn.2096-9600.2025.06.20]
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基于数据挖掘的中医药治疗梅核气的用药规律分析()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年06期
页码:
106-109
栏目:
二次研究
出版日期:
2025-06-15

文章信息/Info

Title:
Data mining-Based Analysis of Medication Rules of TCM Therapy for Globus Hysteriocus
作者:
李志敏1, 殷浩辉1, 郭超峰2
1.广西中医药大学，广西 南宁 530001
2.广西中医药大学第一附属医院，广西 南宁 530023
Author(s):
LI Zhimin1, YIN Haohui1, GUO Chaofeng2
关键词:
梅核气; 中医药; 用药规律; 数据挖掘
Keywords:
globus hysteriocus; TCM; medication rules; data mining
分类号:
R256.49
DOI:
10.12174/j.issn.2096-9600.2025.06.20
文献标志码:
A
摘要:
目的通过中医传承辅助平台（traditional Chinese medicine inheritance support system，TCMISS）分析中药汤剂治疗梅核气的用药规律。 方法在中国知网数据库中检索应用中药汤剂治疗梅核气的相关文献，通过TCMISS分析所选处方的用药频次、四气五味及归经情况，分析组方规律并挖掘新方。 结果筛选得到有效文献166篇，涉及269首方剂及246味中药。其中用药频次＞60次的中药共13味，位居前6味的药物是半夏（193次）、甘草（177次）、茯苓（175次）、厚朴（153次）、柴胡（112次）、桔梗（105次）；五味以苦味、辛味、甘味为主，四气以温性、寒性、平性为主，归经分布以肺经、脾经、胃经为主；关联规则分析得出27对药物组合，涉及中药10味，得出29项关联规则，演化得到4个新处方。 结论梅核气发病以气机失调、痰气互结为主，治以行气开郁化痰，中药汤剂以半夏厚朴汤为基础方进行加减；临床应基于“病痰饮者当以温药和之”“善治痰者，不治痰而治气，气顺则一身之津液亦随气而顺矣”理论进行辨证施治。
Abstract:
ObjectiveTo analyze the medication rules of herbal decoctions in the treatment of globus hysteriocus via TCMISS. MethodsThe literature on herbal decoctions in the treatment of globus hysteriocus were searched from CNKI, the medication frequency, four properties and five flavors, and meridian tropism of the selected prescriptions were analyzed by TCMISS, medication rules were analyzed for the unearthing of new prescriptions. ResultsA total of 166 valid literature were gained, involving 269 prescriptions and 246 herbs, among them, there were 13 herbs with the frequency >60 times, the top six herbs were Banxia (Pinelliae rhizoma, 193 times), Gancao(Glycyrrhizae radix et rhizoma, 177 times), and Fuling [Poria cocos (Schw.) Wol, 175 times], Houpo(Magnoliae officinalis cortex, 153 times), Chaihu (Bupleuri Radix, 112 times) and Jiegeng (Platycodonis radix); and the medicines were bitter, acrid and sweet, of warm, cold and neural, entering the meridians of lung, spleen and stomach; the analysis of association rules displayed 27 pairs of drug combinations, involving ten herbs, 29 items of association rules and four new prescriptions have obtained. Conclusion Qi dysfunction and phlegm intermingling with Qi is the pathogenesis of globus hysteriocus, the disease should be treated by promoting Qi circulation, relieving depression and resolving phlegm, with Banxia Houpu decoction as the basic prescription; syndrome differentiation and treatment should be conducted based on the theory of "patients with phlegm-fluid are treated with warm-nature medicine" and "he who treats phlegm well does not treat phlegm but regulate Qi, body fluid move smoothly with smooth flow of Qi circulation".

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备注/Memo

备注/Memo:
李志敏（1995—），女，硕士学位。研究方向：经方的临床应用与方证关系研究。国家自然科学基金（82060915，81560820）。
更新日期/Last Update: 2025-06-15