[1]索秋实,狄舒男,宋成杰,等.穴位离子导入及中药敷贴联合关节训练对风湿性关节炎风险-效益评价[J].西部中医药,2025,38(06):154-160.[doi:10.12174/j.issn.2096-9600.2025.06.31]
SUO Qiushi,DI Shunan,SONG Chengjie,et al.Risk-benefit Evaluation of Rheumatoid Arthritis Treated with Acupoint Iontophoresis, Herbal Application and Joint Training[J].Western Journal of Traditional Chinese Medicine,2025,38(06):154-160.[doi:10.12174/j.issn.2096-9600.2025.06.31]
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穴位离子导入及中药敷贴联合关节训练对风湿性关节炎风险-效益评价(
)
《西部中医药》[ISSN:2096-9600/CN:62-1204/R]
- 卷:
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38
- 期数:
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2025年06期
- 页码:
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154-160
- 栏目:
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特色医疗
- 出版日期:
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2025-06-15
文章信息/Info
- Title:
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Risk-benefit Evaluation of Rheumatoid Arthritis Treated with Acupoint Iontophoresis, Herbal Application and Joint Training
- 作者:
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索秋实1,2, 狄舒男2, 宋成杰3, 彭宇飞1
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1.黑龙江中医药大学附属第一医院,黑龙江 哈尔滨 150040
2.黑龙江中医药大学,黑龙江 哈尔滨 150040
3.大庆市中医医院,黑龙江 大庆 163000
- Author(s):
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SUO Qiushi1,2, DI Shunan2, SONG Chengjie3, PENG Yufei1
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- 关键词:
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风湿性关节炎; 穴位离子导入; 中药敷贴; 关节训练; 中医综合外治法
- Keywords:
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rheumatoid arthritis; acupoint iontophoresis; herbal application; joint training; TCM comprehensive external treatment
- 分类号:
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R244.9
- DOI:
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10.12174/j.issn.2096-9600.2025.06.31
- 文献标志码:
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B
- 摘要:
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目的基于多准则决策模型评价穴位离子导入及中药敷贴联合关节训练的中医综合外治法治疗风湿性关节炎(rheumatoid arthritis,RA)的效益-风险。
方法将160例RA患者按照随机数字表法分为观察组和对照组各80例。对照组口服倍他米松,观察组在对照组基础上予穴位离子导入及中药敷贴联合关节训练的中医综合外治法。比较两组患者治疗前后中医症候积分、临床体征指标、血清免疫功能指标、外周血象指标变化情况以及临床疗效、不良反应发生情况;建立中医综合外治法治疗RA的多准则决策模型,比较两组患者效益指标和风险指标效应值。
结果治疗后观察组畏寒、关节肿胀、晨僵、关节疼痛积分均低于对照组(P<0.05);观察组双手握力高于对照组(P<0.05),关节压痛指数、晨僵时间、关节肿胀个数均低于对照组(P<0.05);观察组患者免疫功能及外周血象相关指标水平均低于对照组(P<0.05);观察组总有效率[86.25%(69/80)]高于对照组[62.50%(50/80)](P<0.05),不良反应发生率[3.75%(3/80)]低于对照组[13.75%(11/80)](P<0.05)。与对照组相比,观察组治疗效益高、风险低,观察组及对照组的效益-风险总值分别为78、66,且观察组优于对照组,多准则决策评价模型稳定性较好。
结论与传统西医相比,穴位离子导入及中药敷贴联合关节训练组成的中医综合外治法治疗RA的获益高于风险,可用于临床治疗RA。临床上中医综合外治法治疗RA的效益-风险可能优于传统西医治疗。
- Abstract:
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ObjectiveTo assess the risk-benefit of rheumatoid arthritis (RA) treated with TCM comprehensive external treatment including acupoint iontophoresis, herbal application and joint training based on multi-criteria decision making.
MethodsA total of 160 RA patients were allocated to the observation group and the control group according to random number table method with 80 cases in each group. The control group took betamethas-one orally, and the observation group accepted TCM comprehensive external treatment including acupoint iontophoresis, herbal application and joint training. To compare TCM syndrome integrals, the indexes of clinical body signs, serum immune function indexes, the changes in peripheral blood parameters, clinical effects and the incidences of adverse reaction before and after the treatment between the two groups; a multi-criteria decision making model of integrated external treatment for RA was established, and the effect values of benefit indicators and risk indicators were compared between the two groups.
ResultsAfter the treatment, the observation group was lower than the control group in aversion to cold, joint swelling, morning stiffness and joint pain scores (P<0.05); the observation group was higher than the control group in hand grip strength (P<0.05), lower than the control group in joint tenderness indexes, morning stiffness and the number of swollen joints (P<0.05); serum immune function indexes and the changes in peripheral blood parameters of the observation group were lower than these of the control group (P<0.05); total effective rate of the observation group was [86.25% (69/80)], higher than [62.50% (50/80)] of the control group (P<0.05), and the incidence of adverse reaction of the observation group was [3.75%(3/80)], lower than [13.75%(11/80)] of the control group. Compared with the control group, the observation group presents high therapeutic efficiency and low risk, total risk-benefit values of the observation group and the control group were 78 and 66 respectively, and the observation group was better than the control group, and the multi-criteria decision making model showed better stability.
ConclusionCompared with traditional Western medicine, the benefits of TCM comprehensive external treatment including acupoint iontophoresis, herbal application and joint training are higher than the risks in the treatment of RA, hence, it could be applied in clinical treatment of RA. Risk-benefit of TCM comprehensive external treatment in clinic might be better than that of traditional Western medicine.
备注/Memo
- 备注/Memo:
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索秋实(1986—),男,博士学位,主治医师。研究方向:方剂学药效对骨伤科疾病的应用研究。
更新日期/Last Update:
2025-06-15