[1]支文冰,刘洋,李晔,等.哮喘实验动物模型的建立及评价[J].西部中医药,2025,38(11):61-68.[doi:10.12174/j.issn.2096-9600.2025.11.10]
　ZHI Wenbing,LIU Yang,LI Ye,et al.Establishment and Evaluation of Animal Models of Asthma[J].Western Journal of Traditional Chinese Medicine,2025,38(11):61-68.[doi:10.12174/j.issn.2096-9600.2025.11.10]
点击复制

哮喘实验动物模型的建立及评价()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年11期
页码:
61-68
栏目:
研究进展
出版日期:
2025-11-15

文章信息/Info

Title:
Establishment and Evaluation of Animal Models of Asthma
作者:
支文冰1,2, 刘洋1,2, 李晔1,2, 孙婷婷1,2, 王春柳1,2, 张红1,2
1.陕西省中医药研究院，陕西 西安 710003
2.陕西省中医医院，陕西 西安 710003
Author(s):
ZHI Wenbing1,2, LIU Yang1,2, LI Ye1,2, SUN Tingting1,2, WANG Chunliu1,2, ZHANG Hong1,2
1.Shaanxi Academy of Traditional Chinese Medicine, Xi’an 710003, China
2.Shaanxi Provincial TCM Hospital, Xi’an 710003, China
关键词:
支气管哮喘; 动物模型; 变应原; 评价指标
Keywords:
bronchial asthma; animal models; allergen; evaluating indicator
分类号:
R-332
DOI:
10.12174/j.issn.2096-9600.2025.11.10
文献标志码:
A
摘要:
梳理了哮喘典型的病理变化，总结了不同哮喘模式动物的优缺点及常用的变应原、佐剂，分类表述了不同哮喘模型具体的造模过程和评价方式，以期望为临床药物的研发和哮喘动物模型的细化开发提供理论支撑。
Abstract:
We reviewed typical pathological changes of asthma, summed up the advantages and disadvantages of different animal models of asthma, the common allergens and adjuvant, and clarified the specific modeling process and evaluation modes of different animal models of asthma, so as to provide theoretical support for clinical drug research and development, and the improvement of asthma animal models.

相似文献/References:

[1]向建华,毛良平,韩鹏凯,等.沙美特罗替卡松联合金水宝胶囊治疗中度非急性发作期支气管哮喘100例临床观察*[J].西部中医药,2013,26(05):97.
　XIANG Jianhua,MAO Liangping,HAN Pengkai,et al.Observation on Salmeterol Fluticasone Combined with JinShuiBao Capsule for 100 Cases of Moderate Bronchial Asthma during the Period of Non Acute Attack[J].Western Journal of Traditional Chinese Medicine,2013,26(11):97.
[2]吴大斌.益气固本汤合俞募配穴敷贴治疗支气管哮喘45例[J].西部中医药,2014,27(10):127.
[3]祝伟,田浩.川芎嗪联合小剂量雷公藤治疗儿童哮喘急性发作期患儿38例[J].西部中医药,2015,28(02):102.
[4]贾红光,罗永伟,陈超,等.对支气管哮喘患者电话随访式健康教育的效果评价[J].西部中医药,2015,28(12):115.
[5]王盛强.中西医结合治疗发作期支气管哮喘48例[J].西部中医药,2014,27(02):110.
　WANG Shengqiang.Treating 48 Cases of Bronchial Asthma at Attack Stage by Integrative Medicine[J].Western Journal of Traditional Chinese Medicine,2014,27(11):110.
[6]玛丽亚,孙学健,严兴海.新疆昌吉地区238例支气管哮喘发作期患者中医证型分布[J].西部中医药,2013,26(12):63.
　MA Liya,SUN Xuejian,YAN Xinghai.TCM Patterns Distribution of 238 Cases of Bronchial Asthma at Exacerbation Stage in Changji of XinJiang[J].Western Journal of Traditional Chinese Medicine,2013,26(11):63.
[7]张晔敏.川芎平喘合剂治疗慢性持续期支气管哮喘74例[J].西部中医药,2014,27(12):64.
[8]甘雨,马进△,袁媛,等.线栓法制备SD大鼠局灶性脑缺血再灌注模型的实践与评价[J].西部中医药,2018,31(07):12.
　GAN Yu,MA Jin,YUAN Yuan,et al.Practice and Evaluation of Focal Cerebral Ischemia Reperfusion Rat Model Prepared by Middle Cerebral Artery Occlusion[J].Western Journal of Traditional Chinese Medicine,2018,31(11):12.
[9]蓝晓慧,乔赟,赖海艳,等.易蔚教授运用“肺鼻同治”法防治小儿支气管哮喘的临床经验[J].西部中医药,2026,39(07):10.[doi:10.12174/j.issn.2096-9600.2026.07.03]
　LAN Xiaohui,QIAO Yun,LAI Haiyan,et al.Professor Yi Wei?s Clinical Experience in Preventing and Treating Pediatric Bronchial Asthma Using the "Simultaneous Treatment of Lung and Nose" Method[J].Western Journal of Traditional Chinese Medicine,2026,39(11):10.[doi:10.12174/j.issn.2096-9600.2026.07.03]
[10]张津津,朱振刚.环状RNA调控支气管哮喘及中药干预相关研究进展[J].西部中医药,2026,39(09):101.[doi:10.12174/j.issn.2096-9600.2026.09.20]
　ZHANG Jinjin,ZHU Zhengang.Advances in Research on Circular RNA Regulation of Bronchial Asthma and Related Traditional Chinese Medicine Interventions[J].Western Journal of Traditional Chinese Medicine,2026,39(11):101.[doi:10.12174/j.issn.2096-9600.2026.09.20]

备注/Memo

备注/Memo:
陕西省重点研发计划（2021ZDLSF04-06，2022ZDXM-SF-06）；陕西省中医药管理局重点实验室建设项目（“秦药”研发重点实验室）；陕西省中医药管理局科研项目（SZY-KJCYC-2025-ZY-005，SZY-KJCYC-2023-014）；西安市科技计划项目（21YXYJ0100，23YXYJ0165）；陕西省中医药科技创新提质扩能计划项目（TZKN-CXRC-05，2025-CXTD-11）；陕西省中医医院“苗圃培优”项目（2021-13）。支文冰（1992—），女，硕士学位，助理研究
更新日期/Last Update: 2025-11-15