[1]王兰兰,杨程,薛惠天,等.推拿干预骨骼肌纤维化的细胞与分子机制研究进展[J].西部中医药,2025,38(11):74-79.[doi:10.12174/j.issn.2096-9600.2025.11.12]
　WANG Lanlan,YANG Cheng,XUE Huitian,et al.Research Progress of Cellular and Molecular Mechanism of Massage Intervention in Skeletal Muscle Fibrosis[J].Western Journal of Traditional Chinese Medicine,2025,38(11):74-79.[doi:10.12174/j.issn.2096-9600.2025.11.12]
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推拿干预骨骼肌纤维化的细胞与分子机制研究进展()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年11期
页码:
74-79
栏目:
研究进展
出版日期:
2025-11-15

文章信息/Info

Title:
Research Progress of Cellular and Molecular Mechanism of Massage Intervention in Skeletal Muscle Fibrosis
作者:
王兰兰, 杨程, 薛惠天, 孙梦龙, 彭亮
湖南中医药大学，湖南 长沙 410208
Author(s):
WANG Lanlan, YANG Cheng, XUE Huitian, SUN Menglong, PENG Liang
Hunan University of Chinese Medicine, Changsha 410208, China
关键词:
骨骼肌纤维化; 推拿; 细胞外基质
Keywords:
skeletal muscle fibrosis; massage; extracellular matrix
分类号:
R244.0
DOI:
10.12174/j.issn.2096-9600.2025.11.12
文献标志码:
A
摘要:
对近十年来推拿治疗骨骼肌纤维化的相关机制研究的文献进行整理分析，发现推拿直接影响细胞外基质的重构、肌成纤维细胞的活化，细胞外基质的分泌与合成，调节基质金属蛋白酶/基质金属蛋白酶组织抑制剂的比值（MMPs/TIMPs）和细胞外基质的降解，此外推拿还能调节细胞因子和生长因子的表达，减少细胞外基质的合成，为推拿治疗骨骼肌纤维化的基础研究和临床治疗提供思路。
Abstract:
By sorting out and analyzing the literature on the relevant mechanism studies of massage in the treatment of skeletal muscle fibrosis in the recent ten years, massage directly affects the remodeling of extra-cellular matrix and the activation of myofibroblasts, the secretion and synthesis of extracellular matrix, adjusts the ratios of MMPs/TIMPs, and the degradation of extracellular matrix, in addition, massage regulates the expressions of cytokines and growth factors, decreases the synthesis of extracellular matrix, which could provide the thinking for basic study and clinical treatment of massage in the treatment of skeletal muscle fibrosis.

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备注/Memo

备注/Memo:
国家自然科学基金（82174521）。王兰兰（1994—），女，硕士学位。研究方向：推拿治病机理研究。
更新日期/Last Update: 2025-11-15