[1]石恒瑜,秦晨光,周开发,等.丹龙口服液对小儿支气管肺炎痰热闭肺证的疗效及对PCT、CRP水平的影响[J].西部中医药,2026,39(07):163-166.[doi:10.12174/j.issn.2096-9600.2026.07.31]
　SHI Hengyu,QIN Chen?guang,ZHOU Kaifa,et al.Efficacy of Danlong Oral Liquid on Pediatric Bronchopneumonia with Phlegm-Heat Obstructing Lung Syndrome and Its Effects on PCT and CRP Levels[J].Western Journal of Traditional Chinese Medicine,2026,39(07):163-166.[doi:10.12174/j.issn.2096-9600.2026.07.31]
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丹龙口服液对小儿支气管肺炎痰热闭肺证的疗效及对PCT、CRP水平的影响()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年07期
页码:
163-166
栏目:
临床研究
出版日期:
2026-07-12

文章信息/Info

Title:
Efficacy of Danlong Oral Liquid on Pediatric Bronchopneumonia with Phlegm-Heat Obstructing Lung Syndrome and Its Effects on PCT and CRP Levels
作者:
石恒瑜1, 秦晨光2, 周开发3, 刘丽琴1
1.大冶市人民医院,湖北 大冶 435100
2.湖北省妇幼保健院,湖北 武汉 430000
3.钟祥市妇幼保健院,湖北 钟祥 431900
Author(s):
SHI Hengyu1, QIN Chen?guang2, ZHOU Kaifa3, LIU Liqin1
1.Daye People’ s Hospital, Daye 435100, China
2.Hubei Provincial Maternal and Child Health Care Hospital, Wuhan 430000, China
3.Zhongxiang Maternal and Child Health Care Hospital, Zhongxiang 431900, China
关键词:
支气管肺炎; 丹龙口服液; 痰热闭肺证; 降钙素原; C-反应蛋白; 儿童
Keywords:
bronchopneumonia; oral liquid; phlegm-heat obstructing lung; PCT; CRP; children
分类号:
R256.12
DOI:
10.12174/j.issn.2096-9600.2026.07.31
文献标志码:
B
摘要:
目的探讨丹龙口服液治疗小儿支气管肺炎（bronchopneumonia，BP）痰热闭肺证的临床疗效，以及对血清降钙素原（procalcitonin，PCT）、C-反应蛋白（C-reactive protein，CRP）水平的影响。 方法选取支气管肺炎患儿80例，采用随机数字表法分为对照组与治疗组，各40例。两组均予以基础常规治疗；对照组予盐酸氨溴索口服液口服，治疗组在此基础上加用丹龙口服液，两组疗程均为1周。对比两组临床疗效、症状体征消退时间、痰热闭肺证证候积分及血清PCT、CRP炎症指标水平。 结果治疗组总有效率［97.50%（39/40）］高于对照组［77.50%（31/40）］（P＜0.05）。与对照组相比，治疗组咳嗽、发热、肺部湿啰音消失时间及胸部X线片炎症吸收时间均缩短（P＜0.05）。治疗3、7天后，两组痰热闭肺证评分均较治疗前降低（P＜0.05），治疗组降低更明显（P＜0.05）。治疗后，两组PCT、CRP水平均较治疗前下降（P＜0.05），治疗组下降更明显（P＜0.05）。 结论丹龙口服液治疗BP痰热闭肺证疗效显著，可有效改善患儿临床症状、体征及中医证候，抑制炎症反应。
Abstract:
ObjectiveTo discuss clinical efficacy of Danlong oral liquid in the treatment of pediatric bronchopneumonia with phlegm-heat obstructing lung syndrome, and its influence on the levels of PCT and CRP. MethodsA total of 80 children with bronchopneumonia were selected and randomly divided into a control group and a treatment group using a random number table method, with 40 cases in each group. Both groups received routine basic treatment. The control group was given ambroxol hydrochloride oral solution, while the treatment group received Danlong Oral Liquid in addition to the same basic treatment. The course of treatment was one week for both groups. To compare clinical efficacy, the resolution time of symptoms and signs, syndrome score of phlegm-heat obstructing lung pattern, and the levels of serum inflammatory markers PCT and CRP between the two groups. ResultsThe total effective rate in the treatment group was 97.50% (39/40), which was significantly higher than that in the control group [77.50% (31/40)] (P0.05). Compared with the control group, the treatment group showed shortened resolution times for cough, fever, pulmonary moist rales, and inflammatory absorption on chest X-ray (P0.05). After three and seven days of treatment, the syndrome scores of phlegm-heat obstructing lung in both groups decreased compared with before treatment (P0.05), with a more pronounced reduction in the treatment group (P0.05). After treatment, the levels of PCT and CRP in both groups decreased compared with before treatment (P0.05), and the decrease was greater in the treatment group (P0.05). Conclusion Danlong oral liquid is effective in the treatment of pediatric bronchopneumonia with phlegm-heat obstructing lung syndrome, and it could effectively improve the patients’ clinical symptoms, body signs and TCM syndromes, and inhibit inflammatory reactions.

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备注/Memo

备注/Memo:
石恒瑜（1989—），男，主治医师。研究方向：儿童急危重症疾病的救治。
更新日期/Last Update: 2026-07-15