[1]朱诗琴,陈彤,曹增,等.知柏地黄汤治疗老年性阴道炎随机对照试验的Meta分析[J].西部中医药,2026,39(09):45-51.[doi:10.12174/j.issn.2096-9600.2026.09.11]
　ZHU Shiqin,CHEN Tong,CAO Zeng,et al.Zhibai Dihuang Decoction for Senile Vaginitis: A Meta-Analysis of Randomized Controlled Trials[J].Western Journal of Traditional Chinese Medicine,2026,39(09):45-51.[doi:10.12174/j.issn.2096-9600.2026.09.11]
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知柏地黄汤治疗老年性阴道炎随机对照试验的Meta分析()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年09期
页码:
45-51
栏目:
二次研究
出版日期:
2026-09-07

文章信息/Info

Title:
Zhibai Dihuang Decoction for Senile Vaginitis: A Meta-Analysis of Randomized Controlled Trials
作者:
朱诗琴1,2, 陈彤2, 曹增3, 姜国正3, 赵一鸣2, 刘新敏2
1.广州市黄埔区中医医院,广东 广州 510799
2.中国中医科学院广安门医院，北京 100053
3.北京中医药大学，北京 100029
Author(s):
ZHU Shiqin1,2, CHEN Tong2, CAO Zeng3, JIANG Guozheng3, ZHAO Yiming2, LIU Xinmin2
1.Huangpu District Hospital of TCM, Guangzhou 510799, China
2.Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
3.Beijing University of Chinese Medicine, Beijing 100029, China
关键词:
老年性阴道炎; 知柏地黄汤; Meta分析; 随机对照试验
Keywords:
senile vaginitis; Decoction; Meta analysis; randomized controlled trials
分类号:
R271.13
DOI:
10.12174/j.issn.2096-9600.2026.09.11
文献标志码:
A
摘要:
目的系统评价知柏地黄汤治疗老年性阴道炎的临床疗效。 方法检索PubMed、Cochrane Library、Web of Science、Embase、中国知网数据库、万方数据库、中国生物医学文献服务系统、维普数据库关于知柏地黄汤治疗老年性阴道炎的随机对照试验研究文献，使用Revman 5.4软件进行Meta分析。 结果最终纳入随机对照试验18篇，涉及患者1522例。与对照组相比，单独或联合使用知柏地黄汤治疗老年性阴道炎可提高有效率、治愈率，降低复发率、不良反应发生率，改善临床症状，降低阴道pH值，提高阴道健康评分，改善阴道清洁度。 结论单独运用知柏地黄汤治疗或合并西医常规治疗老年性阴道炎效果优于西医常规治疗，但仍需高质量研究论证该结论。
Abstract:
ObjectiveTo systematically evaluate the clinical efficacy of Zhibai Dihuang Decoction in the treatment of senile vaginitis. MethodsRandomized controlled trials (RCTs) on Zhibai Dihuang Decoction for the treatment of senile vaginitis were retrieved from PubMed, Cochrane Library, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), Wanfang Database, Chinese Biomedical Literature Service System (SinoMed), and VIP Database. Meta-analysis was performed using RevMan 5.4 software. ResultsEighteen RCTs involving 1,522 patients were finally included. Compared with the control group, treatment with Zhibai Dihuang Decoction alone or in combination with conventional therapy for senile vaginitis significantly improved the effective rate and cure rate, reduced the recurrence rate and incidence of adverse reactions, alleviated clinical symptoms, lowered vaginal pH, increased vaginal health scores, and improved vaginal cleanliness. Conclusion Zhibai Dihuang Decoction alone or combined with conventional Western medicine was superior to conventional Western medicine alone for senile vaginitis, but this conclusion requires confirmation by high-quality studies.

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[1]刘迎萍,柳树英△,张丽君.知柏地黄汤加味治疗绝经综合征46例[J].西部中医药,2012,25(11):95.
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[2]王 芳,王兴盛.六味地黄汤结合中医体质辨识治疗老年性阴道炎的临床观察[J].西部中医药,2014,27(11):109.
[3]章晓乐,季锋,张保华,等.自制蛇白柏洗液治疗肾虚湿热型老年性阴道炎疗效观察[J].西部中医药,2023,36(05):102.[doi:10.12174/j.issn.2096-9600.2023.05.23]
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备注/Memo

备注/Memo:
国家自然科学基金面上项目（81674011）；中国中医科学院科技创新工程项目（CI2021AO2404）。朱诗琴（1997—），女，硕士学位。研究方向：妇科疾病的中医药临床研究。
更新日期/Last Update: 2026-09-15