[1]杨宏权,贡布东智△,刘玉玲,等.藏药制剂康速能补胶囊的药效学研究[J].西部中医药,2012,25(08):53-56.
　YANG Hong-quan,GONG BU Dong-zhi,LIU Yu-ling,et al.Pharmacodynamics of Tibetan Agent KangSu NengBu Capsule[J].Western Journal of Traditional Chinese Medicine,2012,25(08):53-56.
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藏药制剂康速能补胶囊的药效学研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
25
期数:
2012年08期
页码:
53-56
栏目:
出版日期:
2012-08-15

文章信息/Info

Title:
Pharmacodynamics of Tibetan Agent KangSu NengBu Capsule
文章编号:
1004-6852(2012)08-0053-04
作者:
杨宏权1，贡布东智1△，刘玉玲2，马迎春2，朱喜春2
1 甘南州藏医药研究院，甘肃 合作 747000； 2 甘肃省药品检验所
Author(s):
YANG Hong-quan1, GONG BU Dong-zhi1△, LIU Yu-ling2, MA Ying-chun2, ZHU Xi-chun2
1 Academy of Tibetan Drugs in Gannan Tibetan Autonomous Prefecture, Hezuo 747000, China; 2 Gansu Institute for Drug Control
关键词:
康速能补胶囊; 免疫功能; 药效学; 藏药
Keywords:
KangSu NengBu capsule;  immunity;  pharmacodynamics;  Tibetan drug
分类号:
R285.5
文献标志码:
A
摘要:
目的：观察康速能补胶囊补肾壮阳，提高机体免疫功能的作用机制。方法：采用氢化可的松造成小鼠肾阳虚模型法，观察去势雄性大鼠阴茎勃起潜伏期、附性器官指数以及正常雄性鼠交配能力，研究其壮阳作用；通过小鼠炭末廓清实验和小鼠溶血素测定实验研究其免疫作用。结果：康速能补胶囊能升高氢化可的松肾阳虚模型小鼠降低的体温、体质量；延长游泳时间；提高自主活动的总次数；缩短去势雄性大鼠阴茎勃起时间，提高大鼠前列腺＋精液囊和提肛肌的脏器指数；有增强大鼠交配能力的趋势，延长去势雄性大鼠阴茎勃起潜伏期，提高小鼠的耐缺氧能力，增强小鼠非特异性和体液免疫功能。结论：康速能补胶囊具有补肾壮阳、增强抗应激能力，提高机体免疫力的作用。
Abstract:
Objective: To observe the mechanism of KangSu NengBu capsule whether it could invigorate kidney and Yang as well as improve immunity. Method: Models with kidney-Yang deficiency were established with hydrocortisone. Incubation period of penis erection, accessory sexual organ index and mating ability of normal mice were observed to study the function of invigorating Yang; charcoal clearance test and hemolysin test were performed to study the immunization. Result: KangSu NengBu capsule can raise body temperature and weight of mice models; prolong swimming time; increase total times of autonomic activities; shorten the time of penis erection, improve organ indexes such as prostate, samenblase and levator ani muscle of rats; enhance mating ability, prolong incubation period of penis erection, improve hypoxia tolerance of mice, strengthen nonspecific and humoral immune function of mice. Conclusion: KangSu NengBu capsule has the function of invigorating kidney and Yang, enhancing anti-excitability ability and raising immunity.

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备注/Memo

备注/Memo:
收稿日期：2012-05-25 *基金项目：甘肃省科技攻关计划项目(编号2GS052-A43-008-09) 作者简介：杨宏权(1962—)，男，副主任医师。研究方向：藏医药临床与科研。 △通讯作者：贡布东智(1969—)，男，副主任药师。研究方向：藏药研究。
更新日期/Last Update: 2012-08-15