[1]安文莉.茵栀黄颗粒联合思密达治疗新生儿母乳性黄疸50例疗效观察[J].西部中医药,2013,26(01):95.
　AN Wenli.Observation on Y inZhiHuang Granules and Smecta for 50 Cases of Neonatal Breast Milk Jaundice[J].Western Journal of Traditional Chinese Medicine,2013,26(01):95.
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茵栀黄颗粒联合思密达治疗新生儿母乳性黄疸50例疗效观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年01期
页码:
95
栏目:
出版日期:
2013-01-15

文章信息/Info

Title:
Observation on Y inZhiHuang Granules and Smecta for 50 Cases of Neonatal Breast Milk Jaundice
文章编号:
1004-6852(2013)01-0095-02
作者:
安文莉
镇原县第一人民医院儿科，甘肃 镇原 744500
Author(s):
AN Wenli
Pediatrics of Zhenyuan County the First People’s Hospital, Zhenyuan 744500, China
关键词:
黄疸; 母乳性; 新生儿; 妈咪爱; 茵栀黄
Keywords:
jaundice;  breast milk;  neonatal;  medilac-Vita;  YinZhiHuang granules
分类号:
R722.17
文献标志码:
B
摘要:
目的：观察茵栀黄颗粒联合思密达治疗新生儿母乳性黄疸的临床疗效。方法：采用随机数字表法将100例新生儿母乳性黄疸患儿分为治疗组与对照组各50例。2组患儿均给予常规母乳喂养，同时给予蓝光照射治疗和抚触治疗，2次/d。治疗组在此基础上加用茵栀黄颗粒0.1包/次，3次/d，温水冲服；思密达1.0g，以10%葡萄糖注射液15mL调匀后喂服，3次/d。2组均以治疗7天为1个疗程，直至血清总胆红素含量下降至119.7μmol/L以下停止上述治疗。结果：痊愈率治疗组为72.00%，对照组为58.00%；总有效率治疗组为98.00%，对照组为84.00%。2组治愈率、总有效率相比差异有统计学意义(P＜0.05)。治疗后2组血清总红素值与治疗前相比差异有统计学意义(P＜0.05)；治疗后血清总胆红素值、胆红素日均下降值、治愈时间、住院时间等一般资料2组相比差异有统计学意义(P＜0.05)。结论：茵栀黄颗粒联合思密达治疗新生儿母乳性黄疸临床疗效显著，可明显降低血清总胆红素水平，缩短住院时间。
Abstract:
Objective: To observe clinical effects of YinZhiHuang granules and smecta in treating neonatal breast milk jaundice. Method: One hundred cases were divided into the treatment group and the control group equally with random number table. Both groups received breast milk, also blue light irradiation and caress, twice each day.The treatment group took YinZhiHuang granules, 0.1 package once, three times each day, administered after mixing the medicine with water; smecta 1.0 g, taking after mixing it with 15 mL of 10% glucose injection, three times each day. One course of treatment was seven days, the therapy couldn’t stop until the content of serum total bilirubin decreased to 119.7μmol/L. Result: The cure rates of the treatment group and the control group were 72.00% and 58.00% ; total effective rates of both groups were 98.00% and 84.00% . Comparisons of both groups suggested significant difference in the cure rate and total effective rate(P＜ 0.05). The index of total bilirubin showed significant difference before treating compared with that after treating(P＜0.05); comparisons of both groups demonstrated significant difference in average decline of total bilirubin and bilirubin, healing time, hospitalization time and others (P＜0.05).Conclusion: YinZhiHuang granules and smecta, effective in treating neonatal breast milk jaundice, can obviously decrease the level of serum total bilirubin and shorten the hospitalization days.

参考文献/References:

［1］ 杨锡强，易著文.儿科学［M］.6 版.北京:人民卫生出版社，2004：135.
［2］ 齐晓林.新生儿母乳性黄疸综合征89 例临床分析［J］.山东医药，2008，48(10)：123.
［3］ 阎玉萍.妈咪爱与退黄冲剂联合治疗新生儿母乳性黄疸［J］.中国厂矿医学，2009，22(1)：29.
［4］ 李生洪，贾守宁，马春花.茵栀黄注射液的不良反应及其防治措施［J］.中成药，2009，31(1)：163-164.
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［6］ 王洁翡.间歇蓝光联合思密达治疗新生儿母乳性黄疸效果观察［J］.中国医药导报，2009，6(20)：62-63.
［7］ 胡耀武，盛海英，张金霞.茵栀黄口服液灌肠治疗新生儿高胆红素血症32例［J］.西部中医药，2011，24(12):42-44.
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备注/Memo

备注/Memo:
收稿日期：2012-08-22
作者简介：安文莉(1971—)，女，主治医师。
更新日期/Last Update: 1900-01-01