[1]朱苗蕊,指导：金智生.糖脂平治疗早期糖尿病肾病60例疗效观察*[J].西部中医药,2013,26(03):74-75.
　ZHU Miaorui,Director: JIN Zhisheng.Clinical Observation on TangZhiPing in Treating 60 Cases of Early Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2013,26(03):74-75.
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糖脂平治疗早期糖尿病肾病60例疗效观察*
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年03期
页码:
74-75
栏目:
出版日期:
2013-03-15

文章信息/Info

Title:
Clinical Observation on TangZhiPing in Treating 60 Cases of Early Diabetic Nephropathy
文章编号:
1004-6852(2013)03-0074-02
作者:
朱苗蕊，指导：金智生
甘肃中医学院，甘肃 兰州 730000
Author(s):
ZHU Miaorui，Director: JIN Zhisheng
Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China
关键词:
糖尿病肾病; 糖脂平; 治疗
Keywords:
diabetic nephropathy;  TangZhiPing;  treatment
分类号:
R587.2
文献标志码:
B
摘要:
目的：观察糖脂平加减治疗早期糖尿病肾病的临床疗效。方法：将 60 例早期糖尿病肾病患者分为对照组、治疗组各 30 例。2 组均给予拜阿司匹林、瑞格列奈、血塞通等常规治疗。治疗组同时加用糖脂平，1 剂 /d，水煎服，200 mL/ 次，2 次 /d。2 组均以治疗 15 天为 1 个疗程。治疗期间监测血压及血糖。结果：显效率对照组为 40.00%，治疗组为 60.00%，2 组相比差异有统计学意义(P＜0.05)；总有效率对照组为 73.33％，治疗组为 83.33%，2 组相比差异有统计学意义(P＜0.05)。Scr、TG、TC、β2-MG、mAlb 等指标治疗组改善较对照组明显，2 组相比差异有统计学意义(P＜0.05)。结论：糖脂平治疗早期糖尿病肾病疗效满意。
Abstract:
Objective: To observe clinical effects of modified TangZhiPing capsules in treating early diabetic nephropathy. Method: Sixty patients were allocated into the control group and the treatment group equally. Both groups received routine treatment including aspirin enteric-coated tablets, repaglinide, XueSaiTong injection and others. The treatment groups took TangZhiPing, one dose each day, water decocted, 200mL/time, twice per day. One course of treatment was 15 days. Blood pressure and glucose were monitored during the treatment. Result: Effectual rate of the control group was 40.00%, lower than 60.00% of the treatment group with statistical meaning (P＜ 0.05);Total effective rate of the control group was 73.33% , less than 83.33% of the treatment group with statistical meaning (P＜ 0.05). The treatment group improved greater than the control group in Scr, TG, TC, β2-MG, mAlb and other indexes, comparisons between both groups showed statistical meaning (P＜ 0.05). Conclusion: TangZhiPing in treating early diabetic nephropathy could obtain satisfactory effects.

参考文献/References:

［1］ 陈茜，孙伟.中医诊治糖尿病肾病伴蛋白尿的研究进展［J］.西部中医药，2012，25(3)：104-108. ［2］ 陆菊明，潘长玉.糖尿病肾病的流行病学和诊断标准［J］.中华老年多器官疾病杂志，2002，1(3)：163-165. ［3］ 郑筱萸.中药新药临床研究指导原则［M］.北京：中国医药科技出版社，2002：104-108. ［4］ 罗明祥.中西医结合治疗早期糖尿病肾病 42 例［J］.西部中医药，2011，24(7)：82-83. ［5］ 刘立昌，刘新，冯敏坚，等.壮肾固精方治疗糖尿病肾病Ⅲ期的疗效观察［J］.西部中医药，2012，25(4)：11-12. ［6］ 陈莉娜.益肾降糖丸配合西药治疗早期糖尿病肾病 60 例临床疗效观察［J］.中国医药导报，2011，8(32)：105-106. ［7］ 于梅，迟继铭，张岩岩，等.肾炎消白颗粒对早期糖尿病肾病患者尿白蛋白及血清 TGF-β1的影响［J］.中医药信息，2012，29（1)：43-44.

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备注/Memo

备注/Memo:
收稿日期：2012-11-02 * 基金项目：教育部重点项目（编号 206150)、甘肃省科技支撑计划（编号 0708NKCA127) 作者简介：朱苗蕊(1979—)，女，硕士研究生。研究方向：糖尿病的中西医结合诊治。
更新日期/Last Update: 2013-03-15