[1]胡敏棣,杨有文,李妍怡,等.定眩合剂治疗椎-基底动脉供血不足临床观察[J].西部中医药,2014,27(03):95-97.
　HU Mindi,YANG Youwen,LI Yanyi,et al.Clinical Observation on DingXuan Mixture in Treating Vertebro-basilar Insufficiency[J].Western Journal of Traditional Chinese Medicine,2014,27(03):95-97.
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定眩合剂治疗椎-基底动脉供血不足临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年03期
页码:
95-97
栏目:
出版日期:
2014-03-15

文章信息/Info

Title:
Clinical Observation on DingXuan Mixture in Treating Vertebro-basilar Insufficiency
文章编号:
1004-6852(2014)03-0095-03
作者:
胡敏棣1，杨有文1，李妍怡1，蔺菲2，郭永东2
1 甘肃省中医院，甘肃 兰州 730050； 2 甘肃省中医院白银分院
Author(s):
HU Mindi1, YANG Youwen1, LI Yanyi1, LIN Fei2, GUO Yongdong2
1 Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China; 2 Baiyin Branch of Gansu Provincial Hospital of Traditional Chinese Medicine
关键词:
眩晕; 椎-基底动脉供血不足; 经颅多普勒; 血液流变学; 定眩合剂
Keywords:
vertigo;  vertebro-basilar insufficiency;  transcranial Doppler;  blood rheology;  DingXuan mixture
分类号:
R274.9
文献标志码:
B
摘要:
目的：观察定眩合剂治疗椎-基底动脉供血不足（VBI）的临床疗效。方法：将100例VBI患者随机分为治疗组、对照组各50例，对照组给予西比灵等西医常规治疗，治疗组在对照组治疗的基础上加用定眩合剂，2组患者均以2周为1个疗程，分别于2周、4周时采用TCD检测法检测椎动脉、基底动脉的平均血流速度（Vm），并评价疗效。结果：治疗组和对照组在2周、4周后临床有效率分别为92%、96%和74%、78%，2组比较差异有统计学意义（P＜0.05）；Vm及血液流变学相关指标治疗组治疗2周后与治疗前比较、治疗4周后与治疗2周后比较均有显著改善（P＜0.05）；2组治疗2周、4周后比较差异有统计学意义（P＜0.05）。结论：定眩合剂对VBI具有良好的治疗效果，其作用机制可能与改善患者血液流变学、提高Vm有关。
Abstract:
Objective: To explore therapeutic effects of DingXuan mixture in treating vertebro-basilar insufficiency (VBI). Methods: One hundred of the patients were randomized into the treatment group and the control group. The control group received routine western medicine including sibelium, and the treatment group DingXuan mixture on the foundation of the treatment given to the control group. Two weeks were one course of the treatment; mean velocities(Vm) of vertebral artery and basilar artery were detected by transcranial Doppler(TCD) at the 2nd and 4th weeks respectively to assess clinical effects. Results: Clinical effective rates of the treatment group and the control group were 92% and 96%, 74% and 78% at the 2nd and 4th weeks respectively, the difference had statistical meaning(P＜0.05); Vm and related indexes of blood rheology were improved significantly when the treatment group before treating was compared with that after treating in two weeks, the group after treating in two weeks was compared with the one in four weeks(P＜0.05); the differences showed statistical meaning in Vm and related indexes of blood rheology after treating in two weeks, in four weeks (P＜0.05). Conclusion: DingXuan mixture could obtain better effects in treating VBI, and its mechanism might be related to improve blood rheology and Vm of the patients.

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备注/Memo

备注/Memo:
收稿日期：2013-12-24作者简介：胡敏棣(1966—)，女，主任医师。研究方向：脑血管疾病的中西医结合诊治。
更新日期/Last Update: 2014-03-15