维生素E联合三七治疗早期糖尿病视网膜病变的临床观察*-《西部中医药》

文章信息/Info

Title:: Clinical Observation on Vitamin E Capsule and SanQi in Treating Early Diabetic Retinopathy

Author(s):: DENG Hong, XIE Qing, ZHENG Yunyan, WANG Qingkai; Haikou Municipal People′s Hospital, Haikou 570208, China

摘要:: 目的：观察维生素E胶囊联合三七粉治疗早期糖尿病视网膜病变的临床疗效。方法：将90例(179只眼）早期糖尿病视网膜病变患者随机分为3组。治疗组30例(60只眼），口服维生素E胶丸加三七粉；对照组30例(60只眼），口服羟苯磺酸钙分散片；常规治疗组30例(59只眼），仅对基础疾病进行治疗。用药时间120天。治疗前后对所有患者进行眼底检查及荧光素眼底血管造影、视力、视野检查,同时检测肝肾功能、血液流变学等指标。结果：治疗组和对照组的眼底微血管病变和血液黏度均得到一定程度的改善，眼底水肿减退，微血管瘤减少，与常规治疗组比较差异显著（P＜0.05）。结论:维生素E加三七能改善早期糖尿病视网膜病变视网膜的缺血缺氧状态，促进视网膜水肿和微血管瘤的吸收，延缓视力下降的速度。

Abstract:: Objective: To observe clinical effects of Vitamin E capsule and SanQi (Panax pseudo-ginseng) powder in treating early diabetic retinopathy (DR). Methods: Ninety patients (including 179 eyes) were randomized into three groups. 30 cases of the treatment group (60 eyes), who took Vitamin E capsule and SanQi powder; 30 cases of the control group (60 eyes), who were administered with calcium dobesilate dispersible tablets; and 30 cases of routine treatment group (59 eyes). All the patients were treated for 120 days. Fundus examination, fluorescence fundus angiography, the examinations of sight and visual field of the patients were preformed before and after treating; at the same time, the functions of liver and kidney, blood rheology and others were detected. Results: Microvascular disease of the fundus and blood viscosity in both groups were improved, fundus edema and microaneurysm were relieved, the difference was significant when the treatment group was compared with the control group (P＜0.05). Conclusion: Vitamin E capsule and SanQi powder could improve the state of ischemia and hypoxia in the patients with early DR, promote the absorption of retinal edema and microaneurysm and delay the loss of vision.