[1]成虎.风湿康冲剂联合甲氨喋呤治疗类风湿性关节炎40例临床研究[J].西部中医药,2014,27(06):1-3.
　CHENG Hu.Clinical Study of FengShiKang Granules and Methotrexate in Treating 40 Cases of Rheumatoid Arthritis[J].Western Journal of Traditional Chinese Medicine,2014,27(06):1-3.
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风湿康冲剂联合甲氨喋呤治疗类风湿性关节炎40例临床研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年06期
页码:
1-3
栏目:
出版日期:
2014-06-15

文章信息/Info

Title:
Clinical Study of FengShiKang Granules and Methotrexate in Treating 40 Cases of Rheumatoid Arthritis
文章编号:
1004-6852(2014)06-0001-03
作者:
成虎
通渭县人民医院内科，甘肃 通渭 743300
Author(s):
CHENG Hu
Department of Internal Medicine of Tongwei County People′s Hospital, Tongwei 743300, China
关键词:
关节炎; 类风湿; 风湿康冲剂; 甲氨喋呤
Keywords:
rheumatoid arthritis;  FengShiKang granules;  methotraxate
分类号:
R593.2
文献标志码:
A
摘要:
目的：观察风湿康冲剂联合甲氨喋呤治疗类风湿性关节炎的临床疗效。方法：将80例类风湿性关节炎患者随机分为治疗组与对照组各40例，2组都给予甲氨喋呤治疗，在此基础上治疗组加用风湿康冲剂治疗，2组均于连续治疗12周后评价疗效。结果：总有效率治疗组为95.0%，对照组为80.0%，治疗组疗效明显优于对照组(P＜0.05)。治疗后治疗组患者的疼痛评分、肿胀与功能障碍指数都明显低于对照组(P＜0.05)。血沉(ESR)、C反应蛋白(CRP)和类风湿因子(RF)治疗前后组内比较，差异有统计学意义(P＜0.05)，治疗后组间比较，差异亦有统计学意义(P＜0.05)。治疗后恶心呕吐、皮疹、转氨酶升高、食欲不振等不良反应总发生率治疗组明显低于对照组(P＜0.05)。结论：风湿康冲剂联合甲氨喋呤治疗类风湿性关节炎安全有效，能缓解临床症状，恢复机体的正常免疫功能。
Abstract:
Objective: To explore clinical effects of FengShiKang granules and methotraxate in treating rheumatoid arthritis (RA). Methods: Eighty patients were randomized into the treatment group and the control group, both groups received methotraxate, the treatment group took FengShiKang granules on the foundation of the former therapy, clinical effects were judged when both groups were treated for 12 consecutive weeks. Results: Total effective rate of the treatment group was 95.0%, higher than 80.0% of the control group, the treatment group was better than the control group in curative effects (P＜0.05). The treatment group was lower than the control group remarkably in the pain scale, swelling and dysfunctional indexes after treating (P＜0.05), the difference between before and after treating had statistical meaning in ESR, CRP and RF(P＜0.05), the difference showed statistical meaning between both groups after treating(P＜0.05). Total incidence of adverse reaction including nausea and vomiting, rash, elevated aminotransferase, loss of the appetite and others in the treatment group was lower than the control group after treating (P＜0.05). Conclusion: FengShiKang granules combined with methotraxate are safe and effective in treating RA, the therapy could relieve clinical symptoms and restore normal immunity of the body.

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备注/Memo

备注/Memo:
收稿日期：2013-11-18作者简介：成虎(1962—)，男，副主任医师。研究方向：类风湿性关节炎疾病的中西医结合治疗。
更新日期/Last Update: 2014-06-15