[1]付伟光,齐振勇,李爱军,等.HCY、HS-CRP、LP(a)及 D- 二聚体联合检测在冠心病病程中动态检测意义的研究*[J].西部中医药,2014,27(08):148-151.
点击复制

HCY、HS-CRP、LP(a)及 D- 二聚体联合检测在冠心病病程中动态检测意义的研究*
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年08期
页码:
148-151
栏目:
出版日期:
2014-08-15

文章信息/Info

文章编号:
1004-6852(2014)08-0028-03
作者:
付伟光，齐振勇，李爱军，付静怡，葛俊丽
寿光市人民医院，山东 寿光 262700
关键词:
同型半胱氨酸、血清超敏C-反应蛋白、脂蛋白a和D-二聚体; 冠心病
分类号:
R541.4
摘要:
目的：探讨同型半胱氨酸(HCY)、血清超敏C-反应蛋白(HS-CRP)、脂蛋白a［LP(a)］和D-二聚体(DD)联合检测在冠心病病程中应用的意义。方法：将不同类型的冠心病患者198例：急性心肌梗死(AMI)组46例、稳定型心绞痛(SAP)组54例、不稳定型心绞痛(UAP)组56例、隐匿性冠心病(无症状性心肌缺血)42例设为冠心病组，将同期体检合格的健康人216例设为对照组，分别检测血清HCY、HS-CRP、LP(a)和DD的水平。结果：冠心病组HCY、HS-CRP、LP(a)和DD含量均明显高于对照组(P＜0.05)，对照组上述各项指标均在正常范围内。AMI组、UAP组Hcy、HS-CRP、LP(a)和DD含量明显高于SAP组和无症状性心肌缺血组(P＜0.05)；Hcy、HS-CRP、LP(a)和DD含量随冠心病进展呈逐渐增高趋势；无症状性心肌缺血组，UAP组，SAP组，AMI组四项联合检测的阳性率均高于HCY，Hs-CRP，LP(a)，DD单独检测的阳性率(P＜0.05)；无症状性心肌缺血组，UAP组，SAP组，AMI组四项联合检测的阳性率和单独检测的阳性率随病程延长均逐渐提高。结论：HCY、HS-CRP、LP(a)和DD联合检测能更好地反映冠心病患者的病情程度，可以作为评估冠心病患者病情严重程度的敏感指标，对冠心病的预防和早期诊断及动态监测病情有十分重要的临床价值。

相似文献/References:

[1]马思清 指导：谢春毅.瓜蒌薤白三方防治冠心病的研究现状[J].西部中医药,2012,25(10):118.
　MA Si-qing Director: XIE Chun-yi.Exploration on Three Pieces of GuaLou XieBaiFang in the Prevention of Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2012,25(08):118.
[2]马乔娟.银杏叶提取物对绝经后冠心病妇女冠脉血流及血管弹性的影响[J].西部中医药,2013,26(02):24.
　MA Qiaojuan.Effects of Ginaton on Coronary Blood Flow and Vascular Elasticity of Postmenopausal Women with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(08):24.
[3]王龙,王化良.王化良主任巧用经方治疗冠心病合并焦虑状态经验浅析[J].西部中医药,2013,26(03):39.
　WANG Long,WANG Hualiang.Analysis on Director WA NG Hualiang's Experience of Applying Classic Prescriptions to Coronary Heart Disease Complicated to Anxiety[J].Western Journal of Traditional Chinese Medicine,2013,26(08):39.
[4]马丽.冠心病二级预防用药出院带药情况分析[J].西部中医药,2013,26(07):58.
　MA Li.Analysis on Prescribed Medications for Discharged Patients in Secondary Prevention of Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(08):58.
[5]潘雪晖.综合护理干预对冠心病患者不良生活方式的影响[J].西部中医药,2013,26(07):105.
　PAN Xuehui.Impact of Comprehensive Nursing Intervention on Lifestyles of Patients with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(08):105.
[6]袁春玲.家庭病床冠心病护理可行性探讨[J].西部中医药,2012,25(07):109.
　YUAN Chun-ling.Probe into Feasibility of Nursing for Patients with Coronary Heart Disease in Family Practice[J].Western Journal of Traditional Chinese Medicine,2012,25(08):109.
[7]王凯,林文.丹红与丹参酮ⅡA治疗冠心病心绞痛疗效比较[J].西部中医药,2013,26(08):88.
　WANG Kai,LIN Wen.Comparison between DanHong Injection and Tanshinone ⅡA in Treating Angina Pectoris of Patients with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(08):88.
[8]董瑞萍.阿昔莫斯胶囊对冠心病PCI术后血液流变学及血脂的调节作用[J].西部中医药,2012,25(05):6.
　DONG Rui-ping.Adjustment of Acipimox Capsule on Hemorheology and Blood Lipid in Patients after PCI[J].Western Journal of Traditional Chinese Medicine,2012,25(08):6.
[9]赵云霞,刘正跃.综合护理干预对冠心病患者不良生活方式的影响[J].西部中医药,2012,25(05):105.
　ZHAO Yun-xia,LIU Zheng-yue.Effects of Comprehensive Nursing Intervention on Unhealthy Lifestyle of Patients with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2012,25(08):105.
[10]刘瑞,马超慧.优质护理对冠心病患者满意率的影响[J].西部中医药,2013,26(09):116.
　LIU Rui,MA Chaohui.Effects of High Quality Nursing on Satisfactory Degree of the Patients with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(08):116.

备注/Memo

备注/Memo:
作者简介：付伟光(1962—)，男，副主任技师。研究方向：免疫学。
更新日期/Last Update: 2014-08-15