[1]陈兴元,罗湛滨△,张力,等.中药熏洗方治疗肛门瘙痒用药规律研究[J].西部中医药,2018,31(10):43-45.
　CHEN Xingyuan,LUO Zhanbin,ZHANG Li,et al.The Rules of Herbal Fumigation Prescription in Treating Pruritus Ani Based on Association Rules[J].Western Journal of Traditional Chinese Medicine,2018,31(10):43-45.
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中药熏洗方治疗肛门瘙痒用药规律研究()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年10期
页码:
43-45
栏目:
出版日期:
2018-10-15

文章信息/Info

Title:
The Rules of Herbal Fumigation Prescription in Treating Pruritus Ani Based on Association Rules
文章编号:
1004-6852(2018)10-0043-03
作者:
陈兴元1，罗湛滨2△，张力2，周铂凡1
1 广州中医药大学第二临床医学院，广东 广州 510405； 2 广东省中医院
Author(s):
CHEN Xingyuan1, LUO Zhanbin2△, ZHANG Li2, ZHOU Bofan1
1 The Second Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou 510405, China; 2 Guangdong Provincial Hospital of Traditional Chinese Medicine
关键词:
肛门瘙痒; 熏洗; 组方规律; 关联规则; 中医传承辅助系统
Keywords:
pruritus ani;  fumigation;  the laws of prescription forming;  association rules;  TCMISS
分类号:
R266
文献标志码:
A
摘要:
目的：基于中医传承辅助系统，分析肛门瘙痒中药熏洗处方的用药规律。方法：收集1989年至2016年中国知网、重庆维普、万方数据库收录文献中治疗肛门瘙痒的中药熏洗处方，分析处方中各种药物的使用频次、性味归经及药物之间的关联规则。结果：使用频次前3位的分别是苦参、蛇床子、黄柏。四气频次依次为寒性509次、温性388次、凉性80次、平性43次、热性6次。五味频次依次为苦味722次、辛味465次、甘味223次、酸味68次、涩味53次、淡味16次、咸味12次。归经频次依次为肝经459次、膀胱经447次、肾经390次、胃经369次、脾经297次、心经245次、大肠经236次、肺经218次、心包经21次、胆经17次、小肠经8次、三焦经1次。药物组合出现频次由高到低排序，前3位分别是“苦参，蛇床子”“苦参，黄柏”“地肤子，苦参”。根据同现关系，将中药之间的关联规则用网络视图方式展示，其中居于网络图中间的苦参、蛇床子、黄柏、白鲜皮、地肤子等均为临床熏洗治疗肛门瘙痒最常用中药。结论：肛门瘙痒熏洗常用的药物以清热燥湿、祛风止痒、攻毒杀虫为主，治法主要是清热解毒、祛风燥湿、杀虫止痒。药物四气的分布以寒、温为主，五味的分布以苦、辛、甘为主。药物归经的分布以肝、脾、肾为主。苦参、蛇床子、黄柏、地肤子、白鲜皮、防风、百部是临床中药熏洗治疗肛门瘙痒常用的核心药物。
Abstract:
Objective: To analyze the medication rule of herbal fumigation prescription for pruritus ani based on TCMISS. Methods: Herbal fumigation prescriptions of treating pruritus ani were collected from CNKI, VIP and Wanfang database from 1989 to 2016, the association rules between the herbs, the nature, tastes and the entering meridians, the usage frequency of different herbs were analyzed in the prescriptions. Results: The drugs in the top three frequencies were Kushen (Sophora flavescens), Shechuangzi［Cnidium monnieri(L.)Cuss.］and Huangbo(Cortex Phellodendri Chinensis) respectively. The frequencies of four natures ranked: cold nature 509 times, warm nature 388 times, cool nature 80 times, mild nature 43 times and hot nature six times. The frequencies of five tastes were bitter taste 722 times, pungent taste 465 times, sweet taste 223 times, sour taste 68 times, astringent taste 53 times, light taste 16 times and salty 12 times. The frequencies of the entering meridians were liver meridian 459 times, bladder meridian 447 times, kidney meridian 390 times, stomach meridians 369 times, spleen meridian 297 times, heart meridian 245 times, large intestine 236 times, lung meridian 218 times, pericardium meridian 21 times, gall bladder 17 times, small intestine eight times and triple energizer once. According to the frequencies of the herb combination, the top three combinations were "Kushen-Shechuangzi", "Kushen-Huangbo" and "Difuzi-Kushen". Association rules between the herbs were displayed in the way of network view according to cooccurrence relationship, Kushen, Shechuangzi, Huangbo, Baixianpi, Difuzi and others, which were located in the middle of network, were the commonly-used herbs of treating pruritus ani by fumigation in clinic. Conclusion: The commonly-used herbs of treating pruritus ani by fumigation are mainly of clearing heat, eliminating the dampness, dispelling the wind and stopping the itching, removing toxin and killing worms, therapeutic methods are mainly to clear heat and detoxicating, dispelling wind and removing the dampness, killing the worms and relieving the itching. Four natures of the herbs are cold and warm mainly, the five tastes are bitter, pungent and sweet. The entering meridians of the herbs are liver, spleen and kidney mainly. Kushen, Shechuangzi, Huangbo, Difuzi, Baixianpi, Fangfeng and Baibu are the core herbs which are commonly used for treating pruritus ani by fumigation in clinic.

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备注/Memo

备注/Memo:
收稿日期：2018-02-02 *基金项目：国家中医药管理局中医药标准化项目［编号SATCM-2015-BZ(175)］。 作者简介：陈兴元(1989—)，男，硕士学位，医师。研究方向：中西医结合治疗肛肠疾病。 △通讯作者：罗湛滨(1959—)，男，副主任医师，硕士研究生导师。研究方向：中西医结合治疗肛肠疾病。
更新日期/Last Update: 2018-08-15