[1]安青,吴燕波,李伟兵,等.补精解毒方联合化疗治疗老年中晚期非小细胞肺癌40例[J].西部中医药,2018,31(10):76-79.
　AN Qing,WU Yanbo,LI Weibing,et al.Essence-supplementing Detoxifying Prescription Combined with Chemotherapy in Treating 40 Senile Patients with Advanced Non Small-cell Lung Cancer[J].Western Journal of Traditional Chinese Medicine,2018,31(10):76-79.
点击复制

补精解毒方联合化疗治疗老年中晚期非小细胞肺癌40例()
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年10期
页码:
76-79
栏目:
出版日期:
2018-10-15

文章信息/Info

Title:
Essence-supplementing Detoxifying Prescription Combined with Chemotherapy in Treating 40 Senile Patients with Advanced Non Small-cell Lung Cancer
文章编号:
1004-6852(2018)10-0076-04
作者:
安青1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3，吴燕波1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3，李伟兵1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3，包玉华1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3，俞晨1，2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3
1 江苏省肿瘤医院，江苏 南京 210029； 2 江苏省肿瘤研究所； 3 南京医科大学附属肿瘤医院
Author(s):
AN Qing1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2,3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3, WU Yanbo1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2,3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3, LI Weibing1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2,3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3, BAO Yuhua1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2,3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3, YU Chen1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2,3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3' target="_blank" rel="external">3
1 Jiangsu Provincial Cancer Hospital, Nanjing 210029, China; 2 Jiangsu Provincial Cancer Institute 3 Cancer Hospital Affiliated to Nanjing Medical University
关键词:
肺癌; 补精解毒方; 化疗; 中晚期; 老年人
Keywords:
lung cancer;  essence-supplementing detoxifying prescription;  chemotherapy;  advanced stage
分类号:
R734.2
文献标志码:
B
摘要:
目的：观察补精解毒方联合化疗治疗老年中晚期非小细胞肺癌临床疗效。方法：将80例患者随机分观察组和对照组，每组40例。对照组给予化疗，观察组在对照组治疗的基础上服用补精解毒方。观察2组患者的疾病控制率、临床获益率、体质量增加稳定率及治疗前后KPS评分提高率、毒副反应及化疗周期。结果：疾病控制率2组比较，差异无统计学意义（P＞0.05）。临床获益率、体质量增加稳定率及KPS评分提高率观察组优于对照组（P＜0.05），观察组副反应发生例数少于对照组平均化疗周期长于对照组。结论：补精解毒方联合化疗治疗中晚期非小细胞肺癌能改善患者生活质量，提高疾病控制率和临床获益率，且能够减轻化疗引起的不良反应，增强老年人对化疗的耐受性。
Abstract:
Objective: To observe clinical effects of essence-supplementing detoxifying prescription joined with chemotherapy in treating senile patients with advanced non small-cell lung cancer (NSCLC). Methods: Eighty patients were randomized into the observation group and the control group, 40 cases each group. The control group accepted chemotherapy, while the observation group took essence-supplementing detoxifying prescription on the foundation of the therapy the control group received. The indexes of chemotherapy cycle, toxic and side effects, KPS improvement rate before and after treating, body mass increase stabilization rate, clinical benefit rate and disease control rate of both groups were observed. Results: The difference had no statistical meaning in the comparisons of disease control rate between both groups(P＞0.05). The observation group was superior to the control group in clinical benefit rates body mass increase stabilization rate and KPS scores after treating (P＜0.05), the observation group was less than the control group in the number of the coser suffering adverse reactions，longer than the control group in overage chemollerapy cycle. Conclusion: Essence-supplementing detoxifying prescription joined with chemotherapy in treating senile patients with advanced NSCLC could improve quality of life, raise disease control rate and clinical benefit rate, the method could reduce adverse reaction caused by chemotherapy and enhance the elderly′s tolerance to chemotherapy.

相似文献/References:

[1]毛慧慧.温馨提示卡在肺癌患者健康教育中的应用及评价[J].西部中医药,2012,25(09):98.
　MAO Hui-hui.Evaluation and Application of Cue Card to Health Education of Lung Cancer[J].Western Journal of Traditional Chinese Medicine,2012,25(10):98.
[2]张芳,孟宪明.培土生金法对气虚痰湿型肺癌化疗减毒增效的临床研究[J].西部中医药,2014,27(10):94.
[3]丁明明,吴勉华△.中药对肺癌细胞凋亡诱导基因表达的影响[J].西部中医药,2015,28(05):142.
[4]贡惠娟,赵玉娥,严春亚,等.循证护理对中晚期肺癌患者睡眠质量和自我护理能力的影响[J].西部中医药,2015,28(12):121.
[5]孟立峰,王军仓,王磊,等.麦味地黄丸防治肺癌放疗致放射性肺炎40例临床观察[J].西部中医药,2012,25(07):4.
　MENG Li-feng,WANG Jun-cang,WANG Lei,et al.Observation on MaiWei DiHuangWan in Preventing and Treating 40 Cases of Radiation Pneumonia Induced by Radiotherapy of Lung Cancer[J].Western Journal of Traditional Chinese Medicine,2012,25(10):4.
[6]常云丽.心理护理干预对肺癌患者焦虑、抑郁等负性情绪的影响[J].西部中医药,2012,25(07):117.
　CHANG Yun-li.Influence of Psychological Nursing Intervention on Life Quality of Patients with Lung Cancer[J].Western Journal of Traditional Chinese Medicine,2012,25(10):117.
[7]李静.穴位注射胃复安联合按压翳风穴对肺癌放化疗所致顽固性呃逆效果观察[J].西部中医药,2016,29(03):111.
　LI jing.Observation on Curative Effects of Acupoint Injection of Metoclopramide and Pressing YiFeng in Treating Intractable Hiccup induced by Radiotherapy and Chemotherapy Given to Lung Cancer Patients[J].Western Journal of Traditional Chinese Medicine,2016,29(10):111.
[8]倪军,顾惠英,冯高华.扶正抗瘤方对肺癌化疗患者细胞免疫功能及生活质量的影响[J].西部中医药,2014,27(12):6.
[9]徐玉娥,肖正国,宋薇,等.扶正升白口服液联合NP方案治疗晚期非小细胞肺癌的临床研究[J].西部中医药,2016,29(02):1.
　XU Yue,XIAO Zhengguo,SONG Wei,et al.Clinical Study on FuZheng ShengBai Oral Liquid Combined with NP Regimen in Treating Non Small-cell Lung Cancer at Advanced Stage[J].Western Journal of Traditional Chinese Medicine,2016,29(10):1.
[10]李志静,曹岚.认知行为护理干预对青年肺癌患者心理状况及生存质量的影响[J].西部中医药,2016,29(03):117.
　LI Zhijing,CAO Lan.Impact of Cognitive Behavior Therapy on Psychological State and Quality of Life of Young Patients with Lung Cancer[J].Western Journal of Traditional Chinese Medicine,2016,29(10):117.

备注/Memo

备注/Memo:
收稿日期：2018-04-27 *基金项目：国家自然科学基金项目（编号81503528)；江苏省中医药局科研项目（编号YB2017091). 作者简介：安青（1970—），男，硕士研究生导师，主任医师，教授。研究方向：中西医结合肿瘤临床及基础研究。
更新日期/Last Update: 2018-08-15