复方丹参注射液治疗重度子痫前期产后出血41例-《西部中医药》

文章信息/Info

Title:: Compound DanShen Injection in Treating 41 Cases of Severe Preeclampsia Postpartum Hemorrhage

Author(s):: QU Ping, LI Weiling; Department of Obstetrics, Xi′an GaoXin Hospital, Xi′an 710000, China

Keywords:: severe preeclampsia; compound DanShen injection; postpartum hemorrhage

摘要:: 目的：观察复方丹参注射液对重度子痫前期产后出血的影响。方法：将81例患者按照就诊先后顺序分为2组。对照组41例，给予常规治疗，包括解痉、降压、镇静、高蛋白低脂饮食、合理扩容、适当利尿等。观察组40例，在对照组治疗的基础上加用复方丹参注射液。比较2组治疗前后凝血功能、D-二聚体(D-D)、血小板参数及产后出血情况。结果：凝血功能、D-二聚体(D-D)、血小板参数治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后2组组间比较差异也有统计学意义(P＜0.05)。弥散性血管内凝血、产后出血、失血性休克的发生率及平均产后出血量2组比较，差异均有统计学意义(P＜0.05)。结论：复方丹参注射液可显著降低重度子痫前期孕妇的产后出血量和出血事件发生率，可能与其能够改善凝血功能和血小板参数有关。

Abstract:: Objective：To observe the effects of compound DanShen injection on severe preeclampsia postpartum hemorrhage. Methods: According to the visiting sequence, 81 patients were allocated to two groups. 41 cases of the control group were given conventional therapy including relieving spasm, lowering blood pressure, calming, high protein low fat diet, reasonable dilatation, proper diuresis and others. 40 cases of the observation group accepted compound DanShen injection based on conventional therapy. To compare the conditions of postpartum hemorrhage, platelet parameters, D-D and coagulation function between both groups before and after treating. Results: The difference was found in the comparisons of platelet parameters, D-D and coagulation function within two groups before and after treating (P＜0.05); the difference was found in the comparisons between both groups after treating (P＜0.05). The difference had statistical meaning in the comparisons of the incidences of disseminated intravascular coagulation (DIC), postpartum hemorrhage and hemorrhagic shock and average postpartum hemorrhage between both groups (P＜0.05). Conclusion: Compound DanShen injection could remarkably lower the incidences of postpartum hemorrhage and bleeding event, which might be related to improving coagulation function and platelet parameters.