[1]代成刚,陈广,杨俊杰,等.经穴推拿联合西格列汀对2型糖尿病肥胖患者脂联素及irisin的影响[J].西部中医药,2020,33(07):45-48.[doi:10.12174/j.issn.1004-6852.2020.07.10]
　DAI Chenggang,CHEN Guang,YANG Junjie,et al.Effects of Acupoint Massage and Sitagliptin on Adiponectin and Irisin in Obese Patients with Type Two Diabetes Mellitus[J].Western Journal of Traditional Chinese Medicine,2020,33(07):45-48.[doi:10.12174/j.issn.1004-6852.2020.07.10]
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经穴推拿联合西格列汀对2型糖尿病肥胖患者脂联素及irisin的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
33
期数:
2020年07期
页码:
45-48
栏目:
出版日期:
2020-07-15

文章信息/Info

Title:
Effects of Acupoint Massage and Sitagliptin on Adiponectin and Irisin in Obese Patients with Type Two Diabetes Mellitus
文章编号:
1004-6852(2020)07-0045-04
作者:
代成刚，陈广，杨俊杰，陈敏，覃俊杰，祝维峰
1 广州开发区医院，广东 广州 510730； 2 广州中医药大学附属广州市中医院
Author(s):
DAI Chenggang1, CHEN Guang1, YANG Junjie1, CHEN Min1, QIN Junjie1, ZHU Weifeng 2
1 Guangzhou Development District Hospital, Guangzhou 510730, China; 2 The First Affiliated Hospital of Guangzhou University of Chinese Medicine
关键词:
2型糖尿病; 肥胖; 脂联素; Irisin; 推拿; 西格列汀; 中西医结合
Keywords:
type two diabetes mellitus;  obesity;  adiponectin;  irisin;  massage;  sitagliptin;  integrative medicine
分类号:
R587.1
DOI:
10.12174/j.issn.1004-6852.2020.07.10
文献标志码:
A
摘要:
目的：探讨推拿联合西格列汀对2型糖尿病肥胖患者血清脂联素(adiponectin，ADPN)、鸠尾素(irisin)及糖脂代谢的影响。方法：将2型糖尿病肥胖患者60例随机分为对照组和推拿组各30例。两组均口服西格列汀，推拿组加推拿方法。观察两组患者治疗前后糖脂代谢及ADNP、irisin水平。结果：治疗后两组患者空腹血糖(fasting blood glucose，FBG)、餐后2小时血糖(2-hour postprandial blood glucose,2 hPG)、糖化血红蛋白(glycosylated hemoglobin，HbAlC)、甘油三酯(triglyceride，TG)、总胆固醇(total chole-sterol，TC)均低于治疗前，推拿组低于对照组，脂联素高于治疗前，推拿组高于对照组(P＜0.05)；推拿组治疗后体质指数(body mass index，BMI)、低密度脂蛋白(low density lipoprotein，LDL)低于治疗前，高密度脂蛋白(high density lipoprotein，HDL)、irisin高于治疗前(P＜0.05)；推拿组irisin高于对照组(P＜0.05)。结论：经穴推拿联合西格列汀改善2型糖尿病肥胖患者BMI、血糖、胰岛素抵抗、血脂及提升ADPN的作用优于单用西格列汀，且可提升患者血清irisin浓度。
Abstract:
Objective: To observe the influence of massage combined with sitagliptin on adiponectin, irisin and glucolipid metabolism in obese patients with type two diabetes mellitus (T2DM). Methods: Sixty obese patients were randomized into the control group and the massage group, 30 cases each group. Both groups took sitagliptin orally, the massage group accepted massage. To observe the levels of adiponectin(ADPN), irisin and glucolipid metabolism before and after treating in both groups. Results: After treating, FBG, 2 hPG, HbA1c, TG and TC in both groups after treating were lower than these before treating, the massage group was lower than the control group, ADPN higher than that before treating, the massage group higher than the control group(P＜0.05); BMI and LDL of the massage group after treating were lower than these before treating, HDL and irisin higher than these before treating(P＜0.05); the massage group was higher than the control group in irisin(P＜0.05). Conclusion: Acupoint massage combined with sitagliptin could improve BMI, blood glucose, insulin resistance, blood lipid and lift ADPN, superior to the effects of only sitagliptin, and raise the concentrations of serum irisin.

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备注/Memo

备注/Memo:
收稿日期：2019-02-20*基金项目：广东省中医药局资助项目(20181214)；广州市卫生和计划生育委员会资助项目(20172A011028)。作者简介：代成刚(1985—)，男，在读博士研究生，主治医师。研究方向：代谢病的中西医结合临床与研究。
更新日期/Last Update: 2020-07-15