[1]陈志永,杨媛媛,崔小敏,等.实时直接分析质谱法快速鉴别大果飞蛾藤药材[J].西部中医药,2021,34(02):32-34.[doi:10.12174/j.issn.2096-9600.2021.02.08]
　CHEN Zhiyong,YANG Yuanyuan,CUI Xiaomin,et al.Rapid Identification of Daguo Feieteng by DART-MS[J].Western Journal of Traditional Chinese Medicine,2021,34(02):32-34.[doi:10.12174/j.issn.2096-9600.2021.02.08]
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实时直接分析质谱法快速鉴别大果飞蛾藤药材
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年02期
页码:
32-34
栏目:
质量分析
出版日期:
2021-02-15

文章信息/Info

Title:
Rapid Identification of Daguo Feieteng by DART-MS
作者:
陈志永1, 杨媛媛2, 崔小敏1, 胡静1, 任慧1
1.陕西省中医药研究院，陕西 西安 710003
2.西安市食品药品检验所
Author(s):
CHEN Zhiyong1, YANG Yuanyuan2, CUI Xiaomin1, HU Jing1, REN Hui1
1.Shaanxi Province Academy of Traditional Chinese Medicine, Xi′an 710003, China
2.Xi′an Institute for Food and Drug Control
关键词:
大果飞蛾藤; 定性鉴别; 实时直接分析离子源; 东莨菪素; 绿原酸
Keywords:
qualitative identification; DART; scopoletin; chlorogenic acid
分类号:
R282
DOI:
10.12174/j.issn.2096-9600.2021.02.08
摘要:
目的建立一种大果飞蛾藤药材的快速鉴别方法。 方法采用实时直接分析离子源（direct analysis in real time ionization source，DART）结合离子阱质谱快速鉴别大果飞蛾藤药材，载气温度设为300℃，格栅电压设为+350 V/-200 V。定性鉴别采用比对东莨菪素、绿原酸特征离子和二级质谱进行。 结果该方法供试品制备简单，可以在短时间内得到样品质谱图，实现大果飞蛾藤鉴别。通过对不同批次大果飞蛾藤定性鉴别证明了该方法的可行性。 结论该方法可用于大果飞蛾藤药材的定性鉴别。
Abstract:
ObjectiveTo establish a method for rapid identification of Daguo Feieteng (Porana sinensis Hemsl.). MethodsDART combined with ion trap mass spectrometry was employed to identify Daguo Feieteng quickly, the ionization gas temperature was set to 300℃, grid electrode voltage of DART was set to +350 V/-200 V. Qualitative identification was carried out by comparing the characteristics ions of scopoletin, chlorogenic acid and secondary mass spectrometry. ResultsThe method is simple to prepare the sample, and can obtain the mass spectrum of the sample in a short time to realize the identification of Daguo Feieteng. The feasibility of the method was proved by the qualitative identification of different batches of Daguo Feieteng. ConclusionThe method could be used to qualitative identification of Daguo Feieteng.

相似文献/References:

[1]马新换,张丽.咽炎无糖颗粒中药材的定性鉴别研究[J].西部中医药,2018,31(01):28.
　MA Xinhuan,ZHANG Li.Study on Qualitative Identification of Herbs in Pharyngitis Sugarless Granules[J].Western Journal of Traditional Chinese Medicine,2018,31(02):28.

备注/Memo

备注/Memo:
陈志永（1987—），男，博士学位，副研究员。研究方向：中药质量控制与活性成分。国家自然科学基金青年项目（81603264）；陕西省创新人才推进计划——青年科技新星项目（2018KJXX-073）；陕西省重点研发计划项目资助（2018SF-302，2019SF-302）；西安市科技计划项目［201805103YX11SF37（17），2019115613YX011SF044（13）］。
更新日期/Last Update: 2021-02-15