[1]尚靖智,袁岳鹏,刘淑妍.温补脾肾汤联合左甲状腺素钠片治疗甲状腺功能减退症临床观察[J].西部中医药,2021,34(06):106-109.[doi:10.12174/j.issn.2096-9600.2021.06.26]
　SHANG Jingzhi,YUAN Yuepeng,LIU Shuyan.Clinical Observation on Warm-tonifying Spleen-kidney Decoction and Levothyroxine Sodium Tablets in Treating Hypothyroidism[J].Western Journal of Traditional Chinese Medicine,2021,34(06):106-109.[doi:10.12174/j.issn.2096-9600.2021.06.26]
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温补脾肾汤联合左甲状腺素钠片治疗甲状腺功能减退症临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年06期
页码:
106-109
栏目:
衷中参西
出版日期:
2021-06-15

文章信息/Info

Title:
Clinical Observation on Warm-tonifying Spleen-kidney Decoction and Levothyroxine Sodium Tablets in Treating Hypothyroidism
作者:
尚靖智, 袁岳鹏, 刘淑妍
庆阳市人民医院，甘肃 庆阳 745000
Author(s):
SHANG Jingzhi, YUAN Yuepeng, LIU Shuyan
Qingyang City People′s Hospital, Qingyang 745000, China
关键词:
甲状腺功能减退症; 左甲状腺素钠片; 甲状腺功能; 温补脾肾汤
Keywords:
hypothyroidism; levothyroxine sodium tablets; thyroid function; warm-tonifying spleen-kidney decoction
分类号:
R581.2
DOI:
10.12174/j.issn.2096-9600.2021.06.26
摘要:
目的探讨温补脾肾汤联合左甲状腺素钠片治疗甲状腺功能减退症患者的临床效果。 方法选择甲状腺功能减退症患者180例，随机分为观察组和对照组，每组90例。对照组给予左甲状腺素钠片治疗，观察组在此基础上联合温补脾肾汤进行治疗，比较两组患者临床治疗效果。 结果治疗后两组患者神疲乏力、畏寒肢冷、腰膝酸软、面浮肢肿、纳呆腹胀、性欲减退等症状评分均明显降低，且观察组显著低于对照组（P＜0.05）；治疗后观察组促甲状腺激素（thyroid stimulating hormone，TSH）、抗甲状腺过氧化酶抗体（thyroid peroxidase，TPOAb）和抗甲状腺球蛋白抗体（thyroglobulin antibody，TGAb）水平均明显降低，游离三碘甲腺原氨酸（free triiodothyronine，FT3）、游离甲状腺素（free thyroxine，FT4）、总三碘甲腺原氨酸（triiodothyronine，TT3）、总甲状腺素（thyroxine，TT4）水平均明显升高，与治疗前和对照组比较差异具有统计学意义（P＜0.05）；治疗后两组患者甘油三酯（triglyceride，TG）、总胆固醇（total cholesterol，TC）和低密度脂蛋白胆固醇（low-density lipoprotein，LDL-C）水平均明显降低，与对照组比较观察组降低更明显（P＜0.05）。 结论温补脾肾汤联合左甲状腺素钠片治疗甲状腺功能减退症可有效改善患者的临床症状和甲状腺功能。
Abstract:
ObjectiveTo explore clinical effects of warm-tonifying spleen-kidney decoction and levothy-roxine sodium tablets in the treatment of hypothyroidism. MethodsAll 180 patients were selected and randomly allocated to the observation group and the control group, 90 cases in each group. The control group was treated by levothyroxine sodium tablets, and the observation group were given warm-tonifying spleen-kidney decoction, to compare clinical therapeutic effects between both groups. ResultsThe scores of the symptoms reduced notably such as general lassitude, the chilly sensation and the cold limbs, soreness of waist and knees, puffy face and swollen limbs, anorexia and abdominal distension, hyposexuality and others between both groups after treating, and the observation group was lower than the control group significantly (P<0.05); After treating, the levels of TSH, TPOAb and TGAb of the observation group reduced notably, the levels of FT3, FT4, TT3 and TT4 rose remarkably, the differences were statistically significant when they were compared with these before treating, and these of the control group (P<0.05); the levels of TG, TC, LDL-C decreased in both groups after treating, and the decrease of the observation group was more notable than that of the control group (P<0.05). ConclusionWarm-tonifying spleen-kidney decoction and levothyroxine sodium tablets could effectively improve clinical symptoms of the patients and improve thyroid function.

相似文献/References:

[1]樊艳,郑访江,史晓伟,等.甲状腺功能减退症患者健康心理控制源和应对方式与自我管理行为的相关性分析[J].西部中医药,2023,36(09):91.[doi:10.12174/j.issn.2096-9600.2023.09.20]
　FAN Yan,ZHENG Fangjiang,SHI Xiaowei,et al.Correlation Analysis of Healthy Psychological Control Sources, Coping Styles and Self-management Behaviors in Patients with Hypothyroidism[J].Western Journal of Traditional Chinese Medicine,2023,36(06):91.[doi:10.12174/j.issn.2096-9600.2023.09.20]
[2]蒋桂平,曹会波,王正银.健脾化痰活血汤对甲状腺功能减退症患者甲状腺功能及临床疗效的影响[J].西部中医药,2024,37(07):131.[doi:10.12174/j.issn.2096-9600.2024.07.31]
　JIANG Guiping,CAO Huibo,WANG Zhengyin.Influence of Spleen-invigorating Phlegm-resolving Blood-activating Decoction on Thyroid Function in Patients with Hypothyroidism and Curative Effects[J].Western Journal of Traditional Chinese Medicine,2024,37(06):131.[doi:10.12174/j.issn.2096-9600.2024.07.31]

备注/Memo

备注/Memo:
尚靖智（1979—），男，副主任医师。研究方向：内分泌及代谢性疾病的诊治。甘肃省青年科技基金（1506RJYM325）。
更新日期/Last Update: 2021-06-15