[1]马思遥,任延毅,王雪冰,等.养阴活血类中药复方治疗放射性肺炎的Meta分析[J].西部中医药,2023,36(01):70-78.[doi:10.12174/j.issn.2096-9600.2023.01.17]
　MA Siyao,REN Yanyi,WANG Xuebing,et al.Meta-analysis of Compound Traditional Chinese Medicine of Nourishing-Yin and Promoting Blood Circulation in the Treatment of Radioactive Pneumonia[J].Western Journal of Traditional Chinese Medicine,2023,36(01):70-78.[doi:10.12174/j.issn.2096-9600.2023.01.17]
点击复制

养阴活血类中药复方治疗放射性肺炎的Meta分析
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年01期
页码:
70-78
栏目:
出版日期:
2023-01-15

文章信息/Info

Title:
Meta-analysis of Compound Traditional Chinese Medicine of Nourishing-Yin and Promoting Blood Circulation in the Treatment of Radioactive Pneumonia
作者:
马思遥, 任延毅, 王雪冰, 王沈玉
中国医科大学肿瘤医院/辽宁省肿瘤医院，辽宁 沈阳 110042
Author(s):
MA Siyao, REN Yanyi, WANG Xuebing, WANG Shenyu
Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang 110042, China
关键词:
肺炎; 放射性; 肿瘤; 中西医结合; 养阴活血; Meta分析; 中药复方
Keywords:
pneumonia;  radioactive; tumor; integrated Traditional Chinese and Western medicine; nourishing and promoting blood circulation; Meta analysis; compound traditional Chinese medicine
分类号:
R319
DOI:
10.12174/j.issn.2096-9600.2023.01.17
文献标志码:
A
摘要:
目的利用Meta分析方法对养阴活血类中药复方治疗放射性肺炎的作用进行系统评价。 方法检索PubMed、Embase、Medline、中国期刊全文数据库(China National Knowledge Infrastructure，CNKI)、维普中文科技期刊全文数据库(Vip Chinese Science and Technology Journal Database，VIP)及万方数据库（WanFang Data）等常用中、英文数据库，检索时间为从建库至2020年5月1日，筛选符合纳入标准的文献进行系统评价。 结果共纳入40项研究，涉及2528例患者。总有效率观察组优于对照组（P＜0.01，RR=1.32，95%CI［1.27，1.38］）；治疗后观察组影像学改善优于对照组（P＜0.01，SMD=1.12，95%CI［1.01，1.25］），血浆白细胞介素6(interleukin-6，IL-6)变化较对照组明显（P＜0.01，SMD=-0.96，95%CI［-1.18，-0.75］）；血浆肿瘤坏死因子α(tumor necrosis factor α，TNF-α)、血浆转化生长因子β（transforming growth factor-β,TGF-β)水平两组治疗后比较差异无统计学意义；治疗后观察组VC改善优于对照组（P＜0.01，SMD=0.74，95%CI［0.50，0.99］）；治疗后观察组第一秒用力肺活量/潮气量比值(first second forced vital capacity/tidal volume，FEV1/FVC)百分比缓解优于对照组（P＜0.01，SMD=0.65，95%CI［0.41，0.90］）。 结论养阴活血类中药复方在放射性肺炎患者总有效率、影像学、IL-6水平及肺功能（VC、FEV1/FVC百分比）方面有疗效优势。
Abstract:
ObjectiveTo perform systematic evaluation of compound traditional Chinese medicine of nourishing-Yin and promoting blood circulation in the treatment of radioactive pneumonia by utilizing Meta-analysis method. MethodsThe literature which met the inclusion criteria were searched from PubMed, Embase, Medline, CNKI, VIP and Wanfang, and the retrieval time was from the data building time to May 1, 2020, to conduct systematic evaluation. ResultsA total of 40 studies were included, involving 2528 patients. Total effective rate of the observation group was better than that of the control group (P<0.01, RR=1.32, 95% CI[1.27, 1.38]); after the treatment, the observation group was better than the control group in imaging improvement (P<0.01, SMD=1.12, 95% CI[1.01, 1.25]), the changes of IL-6 were more noticeable than these of the control group (P<0.01, SMD=-0.96, 95% CI[-1.18, -0.75]). The difference had no statistical meaning in the levels of TNF-α and TGF-β between both groups after the treatment. After the treatment, VC improvement of the observation group was better than that of the control group (P<0.01, SMD=0.74, 95% CI[0.50, 0.99]). The observation group was superior to the control group in FEV1/FVC% (P<0.01, SMD=0.65, 95% CI[0.41, 0.90]). ConclusionCompound traditional Chinese medicine of nourishing-Yin and promoting blood circulation owns the advantages in the clinical efficacy of total effective rate, imaging, the levels of IL-6, pulmonary function (VC and FEV1/FVC%) in patients with radioactive pneumonia.

相似文献/References:

[1]周胜涟,龚辉,陈州华.健脾渗湿法治疗放射性肠炎的临床观察[J].西部中医药,2014,27(03):102.
　ZHOU Shenglian,GONG Hui,CHEN Zhouhua.Curative Observation on Therapy for Radioactive Enteritis by the Method of Spleen-invigorating and Dampness-eliminating[J].Western Journal of Traditional Chinese Medicine,2014,27(01):102.
[2]王思明,马兆明.康复新液含漱防治放射性口腔炎30例[J].西部中医药,2014,27(12):66.
[3]于礼建,吴迪,梁昆,等.加味缪氏止泻方治疗急性放射性直肠炎33例[J].西部中医药,2015,28(06):91.[doi:2015/6/16 0:00:00]
[4]李丹,姚丹△.酚妥拉明联合肺部中频理疗在治疗小儿肺炎中的应用[J].西部中医药,2017,30(12):80.
　LI Dan,YAO Dan.Application of Phentolamine Combined with Pulmonary Intermediate Frequency Physiotherapy to the Treatment for Infantile Pneumonia[J].Western Journal of Traditional Chinese Medicine,2017,30(01):80.
[5]王文学,唐宝莉,李小雪.加味麻杏石甘汤治疗痰热郁肺型小儿肺炎157例[J].西部中医药,2019,32(08):82.
　WANG Wenxue,TANG Baoli,LI Xiaoxue.Treating 157 Cases of Infantile Pneumonia of Phlegm-heat Stagnating Lung Pattern with Modified Maxing Shigan Decoction[J].Western Journal of Traditional Chinese Medicine,2019,32(01):82.
[6]王 雷,李盛华,周明旺.新型冠状病毒肺炎疫情下骨伤科疾病的诊疗思考[J].西部中医药,2020,33(S1):11.
　Under the Impact of COVID-9 Epidemic.Reflection on the Diagnosis and Treatment of Orthopedic Diseases[J].Western Journal of Traditional Chinese Medicine,2020,33(01):11.
[7]桑天庆,周红光△.中医药在新型冠状病毒肺炎疫情中的应用[J].西部中医药,2020,33(S1):18.
　SANG Tianqing,ZHOU Hongguang.TCM Applied to Epidemic Situation of COVID-19[J].Western Journal of Traditional Chinese Medicine,2020,33(01):18.
[8]王雷,李盛华,周明旺.新型冠状病毒肺炎疫情下骨伤科疾病的诊疗思考[J].西部中医药,2020,33(03):5.[doi:10.12174/j.issn.1004-6852.2020.03.02]
　WANG Lei,LI Shenghua,ZHOU Mingwang.Reflection on the Diagnosis and Treatment of Orthopedic Diseases Under the Impact of COVID-19 Epidemic[J].Western Journal of Traditional Chinese Medicine,2020,33(01):5.[doi:10.12174/j.issn.1004-6852.2020.03.02]
[9]杨晓慧,何菊邻.中医药治疗小儿肺炎的知识图谱分析[J].西部中医药,2020,33(03):73.[doi:10.12174/j.issn.1004-6852.2020.03.20]
　YANG Xiaohui,HE Julin.Knowledge Map Analysis of TCM in Treating Infantile Pneumonia[J].Western Journal of Traditional Chinese Medicine,2020,33(01):73.[doi:10.12174/j.issn.1004-6852.2020.03.20]
[10]时佳,叶晨,杨宗国,等.非危重型新型冠状病毒肺炎97例临床观察[J].西部中医药,2022,35(03):5.[doi:10.12174/j.issn.2096-9600.2022.03.02]
　SHI Jia,YE Chen,YANG Zongguo,et al.Clinical Observation on 97 Patients with Non-critical Type COVID-19[J].Western Journal of Traditional Chinese Medicine,2022,35(01):5.[doi:10.12174/j.issn.2096-9600.2022.03.02]
[11]燕忠生,魏千程,李俊,等.三种不同功效中药注射制剂治疗放射性肺炎的实验研究[J].西部中医药,2014,27(03):36.
　YAN Zhongsheng,WEI Qiancheng,LI Jun,et al.Experimental Study on Treating Radiation Pneumonitis by Three Kinds of Different Herbal Injections[J].Western Journal of Traditional Chinese Medicine,2014,27(01):36.

备注/Memo

备注/Memo:
马思遥（1986—），女，硕士学位。研究方向：肺癌、结肠癌、乳腺癌及其并发症的中西医结合治疗。辽宁省自然科学基金指导计划（2019-ZD-0579，2019-ZD-0582）；辽宁中医药大学中医脏象理论及应用国家教育部重点实验室开放基金（ZYZX1904）。
更新日期/Last Update: 2023-01-15