[1]刘勇,赵一丁,李文彬,等.当代中医治疗白癜风处方用药规律研究[J].西部中医药,2024,37(01):54-59.[doi:10.12174/j.issn.2096-9600.2024.01.13]
　LIU Yong,ZHAO Yiding,LI Wenbin,et al.Study on the Medication Rules of Prescriptions for Vitiligo Treated by Contemporary Chinese Medicine[J].Western Journal of Traditional Chinese Medicine,2024,37(01):54-59.[doi:10.12174/j.issn.2096-9600.2024.01.13]
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当代中医治疗白癜风处方用药规律研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年01期
页码:
54-59
栏目:
二次研究
出版日期:
2024-01-15

文章信息/Info

Title:
Study on the Medication Rules of Prescriptions for Vitiligo Treated by Contemporary Chinese Medicine
作者:
刘勇, 赵一丁, 李文彬, 闫小宁
陕西省中医医院，陕西 西安 710004
Author(s):
LIU Yong, ZHAO Yiding, LI Wenbin, YAN Xiaoning
Shaanxi Provincial TCM Hospital, Xi'an 710004, China
关键词:
白癜风; 中医药; 用药规律; 数据挖掘; 医案
Keywords:
vitiligo; TCM; medication rules; data mining; medical cases
分类号:
R275.9
DOI:
10.12174/j.issn.2096-9600.2024.01.13
文献标志码:
A
摘要:
目的对中医药治疗白癜风中医医案处方进行频数分析、聚类分析、因子分析、关联规则分析，探究白癜风处方用药规律。 方法运用Excel录入白癜风中医治疗医案处方，运用SPSS 21.0统计软件对录入的中药进行描述性分析、因子分析、聚类分析；运用SPSS modeler 18进行关联规则分析。 结果共纳入117个医案，305首方剂；高频药物中刺蒺藜、当归、补骨脂排前3；补虚药、归肝经药、甘味药、温性药占比最多；因子分析共得到9个因子，聚类分析共得到11个药物组合，关联规则分析共得到药物集团14个；当归+刺蒺藜+补骨脂为关联最密切的药对。 结论白癜风病程中气血不和贯穿始终，临床应重视当归+刺蒺藜+补骨脂药对的配伍应用。
Abstract:
ObjectiveTo explore the medication rules of prescriptions for vitiligo by performing frequency analysis,cluster analysis,factor analysis and association rules analysis of TCM prescriptions for the treatment of vitiligo. MethodsThe prescriptions for TCM therapy of vitiligo were input into Excel,descriptive analysis,factor analysis and cluster analysis of the input herbs were conducted using SPSS21.0 statistical software; association rules analysis was conducted using SPSS modeler 18. ResultsThe study included 117 medical cases and 305 prescriptions; Cijili (Tribulus terrestris L.),Danggui (Angelicae sinensis radix) and Buguzhi (Psoraleae fructus) ranked the top three positions among high-frequency medicines; the herbs of tonifcation,entering the meridian of liver,sweet in taste and warm in nature held the most; nine factors have been yielded by factor analysis,11 drug combinations obtained by cluster analysis and 14 drug groups by association rule analysis; Danggui+Cijili+Buguzhi is the drug group with the highest association. ConclusionImportance should be attached to the compatibility of Danggui+Cijili+Buguzhi in clinic since Qi and blood disharmony is throughout the course of vitiligo.

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备注/Memo

备注/Memo:
刘勇（1992—），男，博士学位，医师。研究方向：中医治疗皮肤病的临床与基础研究。国家自然科学基金（81704087）；国家重点研发计划“中医药现代化研究重点专项”（2018YFC1705303）；陕西省重点产业创新链（2019ZDLSF04-08）；陕西省重点研发计划一般项目（2019SF-312）；陕西省重点研发计划重点项目（2018ZDXM-SF-010）。
更新日期/Last Update: 2024-01-15