[1]王海妹,王梅青,宿佳,等.切开对口引流挂线术联合复方黄柏液熏洗治疗肛周脓肿临床观察[J].西部中医药,2024,37(08):144-147.[doi:10.12174/j.issn.2096-9600.2024.08.33]
　WANG Haimei,WANG Meiqing,SU Jia,et al.Clinical Observation on Treating Perianal Abscess with Incision Thread-drawing Counter-drainage Procedure and Compound Huangbo Liquid Fumigation[J].Western Journal of Traditional Chinese Medicine,2024,37(08):144-147.[doi:10.12174/j.issn.2096-9600.2024.08.33]
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切开对口引流挂线术联合复方黄柏液熏洗治疗肛周脓肿临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年08期
页码:
144-147
栏目:
特色医疗
出版日期:
2024-08-15

文章信息/Info

Title:
Clinical Observation on Treating Perianal Abscess with Incision Thread-drawing Counter-drainage Procedure and Compound Huangbo Liquid Fumigation
作者:
王海妹1, 王梅青2, 宿佳1, 刘博2
1.河北中医学院研究生院，河北 石家庄 050091
2.河北中医学院第一附属医院，河北 石家庄 050000
Author(s):
WANG Haimei1, WANG Meiqing2, SU Jia1, LIU Bo2
1.Graduate School, Hebei University of Chinese Medicine, Shijiazhuang 050091, China
2.First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang 050000, China
关键词:
肛周脓肿; 切开对口引流挂线术; 复方黄柏液; 创面愈合
Keywords:
perianal abscess; incision thread-drawing counter-drainage procedure; compound liquid fumigation; wound healing
分类号:
R266
DOI:
10.12174/j.issn.2096-9600.2024.08.33
文献标志码:
B
摘要:
目的观察切开对口引流挂线术联合复方黄柏液熏洗治疗肛周脓肿（perianal abscess，PA）的临床疗效。 方法将146例PA患者采用分层区组随机化方法分为对照组和观察组各73例。对照组予切开对口引流挂线术治疗，观察组在对照组的基础上予复方黄柏液熏洗，两组均连续治疗4周。评测两组不同时间点症状体征评分、血清激活素A（activin A，ACTA）水平、白细胞介素6（Interleukin-6，IL-6）水平，比较两组创面愈合时间、创面腐肉脱落时间及临床疗效。 结果术后第7、14天时两组肛门疼痛、肛缘水肿、创面渗液、肉芽组织等症状体征评分均较术后1天时降低（P＜0.05），且观察组上述指标评分均低于对照组（P＜0.05）；观察组腐肉脱落时间、创面愈合时间均少于对照组；术后第7、14天时，两组血清ACTA和IL-6水平均较术前降低（P＜0.05），且观察组上述指标均低于对照组（P＜0.05）；两组总有效率无差异（P＞0.05），但观察组复发率低于对照组（P＜0.05）。 结论切开对口引流挂线术联合复方黄柏液治疗PA可抑制机体炎症反应，促进术后创面愈合，降低复发率。
Abstract:
ObjectiveTo observe clinical effects of incision thread-drawing counter-drainage procedure (ITCP) and compound Huangbo liquid fumigation in the treatment of perianal abscess (PA). MethodsAll 146 PA patients were allocated to the control group and the observation group using stratified blocked randomization. The control group was treated with ITCP, and the observation group accepted compound Huangbo liquid fumigation on the foundation of conventional therapy of Western medicine, both groups were treated for four weeks consecu-tively. To detect the scores of the symptoms and body signs at different time points, the levels of activin A (ACTA) and Interleukin-6 (IL-6) in the two groups, to compare wound healing time, the time of carrion shedding and clinical effects between both groups. ResultsThe scores of symptoms and body signs including anal pain, perianal edema, wound exudate and granulation tissue were reduced on the 7th and 14th postoperative days than these on the 1st day after surgery (P<0.05), and the above indexes of the observation group were lower than these of the control group (P<0.05); the observation group was less than the control group in the time of carrion shedding and wound healing time; on the 7th and 14th postoperative days, the levels of serum ACTA and IL-6 of both groups were lowered than these before the operation (P<0.05), and the above indexes of the observation group were lower than these of the control group (P<0.05); there was no differences in total effective rate between both groups (P>0.05), while the recurrence rate of the observation group was lower than that of the control group (P<0.05). ConclusionITCP combined with compound Huangbo liquid fumigation in the treatment of PA could inhibit inflammatory response in the body, promote postoperative wound healing and reduce the recurrence rate.

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备注/Memo

备注/Memo:
王海妹（1994—），女，硕士学位。研究方向：中西医结合外科肛肠方向。河北省中医药管理局项目（2022051）。
更新日期/Last Update: 2024-08-15