[1]杨宏权,贡布东智△,刘玉玲,等.藏药制剂康速能补胶囊的药效学研究[J].西部中医药,2012,25(08):53-56.
 YANG Hong-quan,GONG BU Dong-zhi,LIU Yu-ling,et al.Pharmacodynamics of Tibetan Agent KangSu NengBu Capsule[J].Western Journal of Traditional Chinese Medicine,2012,25(08):53-56.
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藏药制剂康速能补胶囊的药效学研究
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《西部中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
25
期数:
2012年08期
页码:
53-56
栏目:
专题·民族医药
出版日期:
2012-08-15

文章信息/Info

Title:
Pharmacodynamics of Tibetan Agent KangSu NengBu Capsule
文章编号:
1004-6852(2012)08-0053-04
作者:
杨宏权1贡布东智1△刘玉玲2马迎春2朱喜春2
1 甘南州藏医药研究院,甘肃 合作 747000; 2 甘肃省药品检验所
Author(s):
YANG Hong-quan1 GONG BU Dong-zhi1△ LIU Yu-ling2 MA Ying-chun2 ZHU Xi-chun2
1 Academy of Tibetan Drugs in Gannan Tibetan Autonomous Prefecture, Hezuo 747000, China; 2 Gansu Institute for Drug Control
关键词:
康速能补胶囊免疫功能药效学藏药
Keywords:
KangSu NengBu capsule immunity pharmacodynamics Tibetan drug
分类号:
R285.5
文献标志码:
A
摘要:
目的:观察康速能补胶囊补肾壮阳,提高机体免疫功能的作用机制。方法:采用氢化可的松造成小鼠肾阳虚模型法,观察去势雄性大鼠阴茎勃起潜伏期、附性器官指数以及正常雄性鼠交配能力,研究其壮阳作用;通过小鼠炭末廓清实验和小鼠溶血素测定实验研究其免疫作用。结果:康速能补胶囊能升高氢化可的松肾阳虚模型小鼠降低的体温、体质量;延长游泳时间;提高自主活动的总次数;缩短去势雄性大鼠阴茎勃起时间,提高大鼠前列腺+精液囊和提肛肌的脏器指数;有增强大鼠交配能力的趋势,延长去势雄性大鼠阴茎勃起潜伏期,提高小鼠的耐缺氧能力,增强小鼠非特异性和体液免疫功能。结论:康速能补胶囊具有补肾壮阳、增强抗应激能力,提高机体免疫力的作用。
Abstract:
Objective: To observe the mechanism of KangSu NengBu capsule whether it could invigorate kidney and Yang as well as improve immunity. Method: Models with kidney-Yang deficiency were established with hydrocortisone. Incubation period of penis erection, accessory sexual organ index and mating ability of normal mice were observed to study the function of invigorating Yang; charcoal clearance test and hemolysin test were performed to study the immunization. Result: KangSu NengBu capsule can raise body temperature and weight of mice models; prolong swimming time; increase total times of autonomic activities; shorten the time of penis erection, improve organ indexes such as prostate, samenblase and levator ani muscle of rats; enhance mating ability, prolong incubation period of penis erection, improve hypoxia tolerance of mice, strengthen nonspecific and humoral immune function of mice. Conclusion: KangSu NengBu capsule has the function of invigorating kidney and Yang, enhancing anti-excitability ability and raising immunity.

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备注/Memo

备注/Memo:
收稿日期:2012-05-25 *基金项目:甘肃省科技攻关计划项目(编号2GS052-A43-008-09) 作者简介:杨宏权(1962—),男,副主任医师。研究方向:藏医药临床与科研。 △通讯作者:贡布东智(1969—),男,副主任药师。研究方向:藏药研究。
更新日期/Last Update: 2012-08-15