[1]付彦俐.淮河流域早期食管癌内镜碘染色普查与中医证型关系的研究[J].西部中医药,2013,26(05):62-65.
　FU Yanli.Study on the Relationship between Patterns and Endoscopic Iodine Staining in the Investigation of Early Esophageal Cancer around Huaihe River Basin[J].Western Journal of Traditional Chinese Medicine,2013,26(05):62-65.
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淮河流域早期食管癌内镜碘染色普查与中医证型关系的研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年05期
页码:
62-65
栏目:
出版日期:
2013-05-15

文章信息/Info

Title:
Study on the Relationship between Patterns and Endoscopic Iodine Staining in the Investigation of Early Esophageal Cancer around Huaihe River Basin
文章编号:
1004-6852(2013)05-0062-04
作者:
付彦俐
洪泽县中医院，江苏 淮安 223100
Author(s):
FU Yanli
Hongze County TCM Hospital, Huaian 223100, China
关键词:
食管癌; 内镜; 碘染色; 辨证分型
Keywords:
esophageal cancer;  endoscope;  iodine staining;  syndrome differentiation and patterns
分类号:
R735.1
文献标志码:
A
摘要:
目的：探讨内镜碘染色法对淮河流域早期食管癌普查的应用效果以及中医辨证分型特点。方法：在食管癌高发区淮河流域对 2 004 例 40～69 岁人群进行内镜检查，观察并记录食管黏膜颜色、形态和黏膜下血管纹理，行组织活检，并搜集中医四诊资料用以辨证分型。结果：碘染色前后诊断发现食管癌患者分别为 25 例、48 例，中度和重度异型增生分别为 208例、64 例；活检组织学诊断发现食管癌患者57 例，中度和重度异型增生272 例。食管癌发现率染色前后相比差异有统计学意义（P＜0.01）。中医不同证型在病变部位、病理类型上差异无统计学意义，而不同证型在病变大小、恶化程度上差异有统计学意义(P＜0.01)。结论：内镜检查中碘染色可明显提高浅表食管癌和异型增生的发现率；食管癌患者中医证型与病变大小、恶性程度相关；重视早期临床症状和内窥镜检查是提高食管癌诊断水平的主要方法。
Abstract:
Objective: To explore the effects of endoscopic iodine staining method in the investigation of earlyesophageal cancer (EC) around Huaihe river basin and its features of syndrome differentiation and patterns. Method:All 2 004 patients aging 40 to 69 in the basin of Huaihe river were examined with endoscope, the color and the morphology of esophageal mucous membrane, vascular lake beneath mucous membrane were observed and recorded, biopsy of tissue was performed and the data about four diagnostic methods was collected for syndrome differentiation and patterns. Result: Before and after iodine staining, there were 25 cases and 48 cases diagnosed with EC, 208 cases and 64 cases with moderate and severe dysplasia; the results of tissue biopsy demonstrated 57 patients with EC, 272 cases with moderate and severe dysplasia. The difference between before and after staining had statistical meaning in the discovery rate of EC (P＜0.01). The difference of patterns had no statistical meaning in the locations of pathological changes and types, it had statistical meaning in the degrees of pathological changes and malignancy (P＜0.01). Conclusion: Iodine staining in the endoscopy could remarkably increase the discovery rate of superificial esophageal cancer and dysplasia; the pattern of patients suffering from EC is related to the degrees of pathological changes and malignancy; early clinical symptom and endoscopy are the primary method of improving the diagnosis of EC.

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备注/Memo

备注/Memo:
收稿日期：2012-10-27 作者简介：付彦俐(1974—)，男，副主任医师。研究方向：脾胃病的中医诊治。
更新日期/Last Update: 2013-05-15