[1]王晓怀,潘文,康开彪,等.黄芪注射液治疗不稳定型心绞痛的系统评价[J].西部中医药,2013,26(10):61-64.
　WANG Xiaohuai,PAN Wen,KANG Kaibiao,et al.Systematic Review on HuangQi Injection in Treating Unstable Angina Pectoris[J].Western Journal of Traditional Chinese Medicine,2013,26(10):61-64.
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黄芪注射液治疗不稳定型心绞痛的系统评价
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年10期
页码:
61-64
栏目:
出版日期:
2013-10-15

文章信息/Info

Title:
Systematic Review on HuangQi Injection in Treating Unstable Angina Pectoris
文章编号:
1004-6852(2013)10-0061-04
作者:
王晓怀1，潘文2，康开彪2，柳树英2，袁仁智1
1 甘肃省中医院，甘肃 兰州 730050； 2 甘肃省中医药研究院
Author(s):
WANG Xiaohuai1, PAN Wen2, KANG Kaibiao2, LIU Shuying2, YUAN Renzhi1
1 Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China; 2 Gansu Provincial Academy of Chinese Medicine
关键词:
黄芪注射液; 不稳定型心绞痛; 系统评价
Keywords:
HuangQi injection;  unstable angina pectoris;  systematic review
分类号:
R972+.3
文献标志码:
A
摘要:
目的：评价黄芪注射液治疗不稳定型心绞痛的疗效与安全性。方法：计算机检索MEDLINE、EMbase、Cochrane图书馆、CNKI、VIP和万方数据库，按照纳入与排除标准由两位研究者独立筛选和提取资料，采用Cochrane协作网随机对照试验的质量评价标准评价纳入文献质量，使用RevMan 5.2软件进行Meta分析。结果：共纳入6篇文献，714例患者。Meta分析结果显示：黄芪注射液组的临床疗效[RR=1.21，95%CI（1.12,1.30）]和心电图改善情况[RR=1.30，95%CI（1.15,1.46）]均优于对照组，2组相比差异有统计学意义。纳入的6篇文献中，4篇文献报道未见明显不良反应，2篇未提及安全性或不良反应。结论：黄芪注射液治疗不稳定型心绞痛，较其他常规西药和中药，可以提高其治疗效果。但由于本系统评价纳入研究质量低且样本量小，药物安全性不明确，尚需高质量随机对照试验进一步验证。
Abstract:
Objective: To evaluate therapeutic effects and the safety of HuangQi injection in treating unstable angina pectoris(UAP). Method: MEDLINE, EMbase, Cochrane library, CNKI, VIP and Wangfang database were searched; data was screened and abstracted by two investigators according to the standard of inclusion and exclusion, the quality of included literature was assessed by quality assessment of randomized controlled trial from Cochrane net and Meta analysis was performed by RevMan 5.2 software. Result: Six pieces of writing were included and 714 patients were involved. The results of Meta analysis showed: HuangQi injection group was superior to the control group in clinical effects [RR=1.21，95%CI（1.12,1.30）] and the improvements of ECG[RR=1.30，95%CI（1.15,1.46）], the difference had statistical meaning. Among six pieces of writing, there was no obvious adverse reaction in four articles, there was no safety and adverse reaction mentioned in two articles. Conclusion: HuangQi injection in treating UAP could improve therapeutic effects than other routine western medicine and herbs. Since low quality of the included research, small sample size and undefined safety of the medicine, the results need to be testified in high quality randomized controlled trials.

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备注/Memo

备注/Memo:
收稿日期：2013-04-10 作者简介：王晓怀(1981—)，男，硕士学位，医师。研究方向：医学信息、循证医学的研究。
更新日期/Last Update: 2013-10-15