[1]贾国龙,邓强,张雪霞.参附注射液对老年膝关节置换术围术期循环稳定性的影响[J].西部中医药,2014,27(06):99-100.
 JIA Guolong,DENG Qiang,ZHANG Xuexia.Effects of ShenFu Injection on Hemodynamics of Senile Patients with Knee Replacement in Perioperative Period[J].Western Journal of Traditional Chinese Medicine,2014,27(06):99-100.
点击复制

参附注射液对老年膝关节置换术围术期循环稳定性的影响
分享到:

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年06期
页码:
99-100
栏目:
出版日期:
2014-06-15

文章信息/Info

Title:
Effects of ShenFu Injection on Hemodynamics of Senile Patients with Knee Replacement in Perioperative Period
文章编号:
1004-6852(2014)06-0099-02
作者:
贾国龙邓强,张雪霞
甘肃省中医院,甘肃 兰州730050
Author(s):
JIA Guolong, DENG Qiang, ZHANG Xuexia
Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
参附注射液膝关节置换术血流动力学心功能
Keywords:
ShenFu injection knee replacement hemodynamics heart function
分类号:
R687.4
摘要:
目的:观察参附注射液对老年患者膝关节置换术围术期循环稳定性的影响。方法:选择60例行膝关节置换术老年患者随机分为参附组和对照组各30例。参附组在麻醉前将1 mL/kg的参附注射液溶于200 mL的生理盐水中,术前20分钟内输完,对照组则使用同等量的生理盐水代替。2组均采用腰麻-硬膜外联合麻醉。观察麻醉前(T1)、麻醉后(T2)、胫骨扩髓后(T3)、放骨水泥后(T4)、术毕松止血带后(T5)5个时间点的收缩压(SBP)、舒张压(DBP)、HR、SpO2、中心静脉压(CVP)。结果:参附组T2、T3及T5时间点时CVP升高(P<0.05),T3、T4及T5时间点时SBP、DBP降低、HR升高(P<0.01)。T2时间点2组CVP比较差异有统计学意义(P<0.05);T3、T4及T5时间点2组SBP、DBP及HR比较差异均有统计学意义(P<0.05)。结论:参附注射液用于老年人膝关节置换术可明显增强心肌泵功能,保持血流动力学平稳。
Abstract:
Objective: To explore the effects of ShenFu injection on hemodynamics of senile patients with knee replacement in perioperative period. Methods: Sixty patients were randomly allocated to ShenFu group and the control group. Before anaesthesia, ShenFu group accepted intravenous injection of ShenFu injection, 1mL/kg, which was dissolved in physiological saline, 200mL, finished in 20 minutes before the surgery, and the control group with the same amount of physiological saline. Both groups received combined spinal and epidural anesthesia. SBP, DBP, HR, SpO2 and CVP were observed at five time points including before (T1) and after anesthesia (T2), after tibia reaming (T3), after placing bone cement(T4) and after releasing tourniquet when the operation was over(T5). Results: CVP was increased at T2, T3 and T5 of ShenFu group (P<0.05), SBP and DBP were decreased but HR was raised at T3, T4 and T5 (P<0.01). The difference showed statistical meaning at T2 between both groups (P<0.05); the difference demonstrated statistical meaning in SBP, DBP and HR at T3, T4 and T5 between both groups (P<0.05). Conclusion: ShenFu injection applied to senile patients with knee replacement could significantly increase myocardial pumping function and keep hemodynamics stable.

相似文献/References:

[1]薛建军,张凌云,贾国龙,等.参附注射液对心肌缺血再灌注老年大鼠NF—κB p65及COX—2表达的影响[J].西部中医药,2012,25(08):14.
 XUE Jian-jun,ZHANG Ling-yun,JIA Guo-long,et al.Influence of ShenFu Injection on Expressions of NF-κB p65 and COX-2 in Aged Myocardial Ischemia Reperfusion Rat Model[J].Western Journal of Traditional Chinese Medicine,2012,25(06):14.
[2]于妍,王硕仁△.参附注射液对肥大心肌细胞能量代谢变化的影响*[J].西部中医药,2013,26(12):11.
 YU Yan,WANG Shuoren.Effects of ShenFu Injection on Energy Metabolism of Hypertrophic Myocardial Cells[J].Western Journal of Traditional Chinese Medicine,2013,26(06):11.
[3]陈 慧,梁晓燕,李旭升,等.独一味胶囊在膝关节置换术后疼痛治疗中的应用[J].西部中医药,2014,27(11):92.
[4]杨晓霞,丁延虹△,杨衍涛,等.参附注射液对慢性充血性心力衰竭患者血清BNP、CRP、TNF-α、IL-6水平的影响[J].西部中医药,2012,25(09):3.
 YANG Xiao-xia,DING Yan-hong,YANG Yan-tao,et al.Effect of ShenFu Injection on Levels of BNP, CRP, TNF-α and IL-6 in Serum of Patients with Chronic Congestive Heart Failure[J].Western Journal of Traditional Chinese Medicine,2012,25(06):3.
[5]王晨,杜自忠,张燕琴,等.参附注射液联合前列地尔治疗血管成形术后缺血再灌注损伤44例[J].西部中医药,2014,27(02):97.
 WANG Chen,DU Zizhong,ZHANG Yanqin,et al.Shenfu Injection and Alprostadil in Treating 44 Cases of Ischemia Reperfusion Injury after Angioplasty[J].Western Journal of Traditional Chinese Medicine,2014,27(06):97.
[6]薛建军,呼荟茹,齐兵献,等.参附注射液对心肌缺血再灌注老年大鼠NF-κB及IκB-α表达的影响*[J].西部中医药,2013,26(02):18.
 XUE Jianjun,HU Huiru,QI Bingxian,et al.Effects of ShenFu Injection on Expressions of NF-κB and IκB-α in Aged Rats with Myocardial Ischemia and Reperfusion[J].Western Journal of Traditional Chinese Medicine,2013,26(06):18.
[7]任莉莉,问明,季静,等.参附注射液联合细胞因子对人慢性髓性白血病细胞来源树突状细胞诱导生成的影响[J].西部中医药,2014,27(07):4.
 REN Lili,WEN Ming,JI Jing,et al.Influence of ShenFu Injection Combined with Cytokines on the Induction and Generation of Dendritic Cells in the Patients with Chronic Myelogenous Leukemia[J].Western Journal of Traditional Chinese Medicine,2014,27(06):4.
[8]侯怀晶,张凌云,薛建军△,等.围术期穴位电刺激联合不同术后镇痛预防TKA后DVT形成的临床随机对照研究[J].西部中医药,2018,31(02):9.
 HOU Huaijing,ZHANG Lingyun,XUE Jianjun,et al.Clinical Randomized Controlled Study of TEAS during Perioperative Period Combined with Different Postoperative Analgesia Methods in Preventing the Formation of DVT after TKA[J].Western Journal of Traditional Chinese Medicine,2018,31(06):9.
[9]陈绍琳,段宗强△.补阳还五汤联合参附注射液治疗冠心病心绞痛100例[J].西部中医药,2018,31(12):86.
 CHEN Shaolin,DUAN Zongqiang.BuYang HuanWu Decoction Combined with ShenFu Injection in Treating 100 Cases of Coronary Heart Disease Angina Pectoris[J].Western Journal of Traditional Chinese Medicine,2018,31(06):86.
[10]郭守强,周永强.参附注射液对外伤性脾破裂患者腹腔镜脾切除术后胃肠功能的影响[J].西部中医药,2019,32(03):80.
 GUO Shouqiang,ZHOU Yongqiang.Effects of ShenFu Injection on Gastrointestinal Function Recovery of the Patients with Traumatic Splenic Rupture after Laparoscopic Splenectomy[J].Western Journal of Traditional Chinese Medicine,2019,32(06):80.

备注/Memo

备注/Memo:
收稿日期:2013-12-10作者简介:贾国龙(1976—),男,主治医师。研究方向:临床麻醉。
更新日期/Last Update: 2014-06-15