[1]苏奋翔,张艳霞,安方玉,等.林氏降脂方对高脂血症大鼠血脂和血液流变学的影响[J].西部中医药,2015,28(10):12-14.
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林氏降脂方对高脂血症大鼠血脂和血液流变学的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
28
期数:
2015年10期
页码:
12-14
栏目:
方药·药理研究
出版日期:
2015-10-15

文章信息/Info

文章编号:
1004-6852(2015)10-0012-03
作者:
苏奋翔1张艳霞2安方玉2李明淑1陈绍仪3
1 甘肃省中医院白银分院,甘肃 白银 730900; 2 甘肃中医药大学; 3 白银市第二人民医院
关键词:
林氏降脂方高脂血症血脂大鼠
分类号:
R285.5
文献标志码:
A
摘要:
目的:观察林氏降脂方对高脂血症大鼠血脂及血液流变学指标的影响。方法:取60只雄性SD大鼠,随机分为正常对照组,模型组,脂脉康胶囊组,林氏降脂方高(1.296 2 g/mL)、中(0.648 1 g/mL)、低剂量组(0.324 1 g/mL),每组10只。正常对照组普通饲料喂养,其余各组高脂乳剂联合高脂饲料喂养建立高脂血症模型并按实验方案给药,6周后,处死各组大鼠,测定血清血脂水平及血液流变学指标。结果:与模型组相比较,脂脉康胶囊组及林氏降脂方高剂量组胆固醇(TC),甘油三酯(TG),低密度脂蛋白(LDL)均明显降低(P<0.05),高密度脂蛋白(HDL-C)明显升高(P<0.05),与模型组相比较,脂脉康胶囊组及林氏降脂方高、中、低剂量组高切、中切、低切全血黏度均明显降低(P<0.05)。结论:林氏降脂方可改善高脂血症大鼠血脂及血液流变学状态。

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备注/Memo

备注/Memo:
*基金项目:甘肃省中医药管理局科研项目(编号GZK-2013-70 )。作者简介:苏奋翔(1963—),男,主任医师。研究方向:脾胃病的诊治。
更新日期/Last Update: 2015-10-15