[1]张旭辉,杨虹.咳喘宁胶囊治疗稳定期慢性阻塞性肺疾病的疗效评价[J].西部中医药,2016,29(03):1-4.
 ZHANG Xuhui,YANG Hong.Evaluation of Clinical Effects of KeChuanNing Capsules in Treating Chronic Obstructive Pulmonary Disease at Stable Stage[J].Western Journal of Traditional Chinese Medicine,2016,29(03):1-4.
点击复制

咳喘宁胶囊治疗稳定期慢性阻塞性肺疾病的疗效评价()
分享到:

《西部中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
29
期数:
2016年03期
页码:
1-4
栏目:
论著·临床论著
出版日期:
2016-03-15

文章信息/Info

Title:
Evaluation of Clinical Effects of KeChuanNing Capsules in Treating Chronic Obstructive Pulmonary Disease at Stable Stage
文章编号:
1004-6852(2016)03-0001-04
作者:
张旭辉杨虹
甘肃中医药大学附属医院,甘肃 兰州 730020
Author(s):
ZHANG Xuhui YANG Hong
University Hospital of Gansu Traditional Chinese Medicine, Lanzhou 730020, China
关键词:
慢性阻塞性肺疾病疗效评价随机对照试验咳喘宁胶囊
Keywords:
chronic obstructive pulmonary disease evaluation on clinical effects randomized controlled trial KeChuanNing capsules
分类号:
R563
文献标志码:
A
摘要:
目的:观察咳喘宁胶囊治疗稳定期慢性阻塞性肺疾病(COPD)的临床疗效。方法:将COPD稳定期患者100例按照随机数字表法随机分为治疗组和对照组各50例。2组患者均口服茶碱缓释片0.1 g/次,2次/d,治疗组患者在此基础上口服咳喘宁胶囊,4粒/次,3次/d;对照组患者在此基础上口服等剂量安慰剂胶囊,4粒/次,3次/d,2组疗程均为3个月。观察临床疗效及BODE指数评分、体质指数(BMI)、肺功能、呼吸困难程度、6分钟步行距离测试(6MWD)、生活质量、安全性。结果:2组患者临床疗效比较治疗组优于对照组,ITT:Z=-1.96,P=0.041;PP:Z=-2.01,P=0.039;治疗组治疗后BODE指数和CAT量表评分明显下降(P<0.05)。结论:咳喘宁胶囊能有效降低稳定期COPD患者BODE指数及CAT评分,提高患者生活质量和临床疗效,且未发现明显毒副作用。
Abstract:
Objective: To observe clinical effects of KeChuanNing capsules in treating chronic obstructive pulmonary disease (COPD) at stable stage. Methods: One hundred patients were divided into the treatment group and the control group according to random number table, 50 cases each group. Both groups took theophylline sustained-release tablets, 0.1g each time, twice per day, the treatment group took KeChuanNing capsules, four pills each time, three times per day; the control group were administered with placebo capsules in equivalent dose, four pills each time, three times per day, both groups were treated for three months. Clinical effects, BODE index scales, body mass index(BMI), pulmonary function, dyspnea degree, six minutes walking test(6MWD), quality of life and the safety were observed. Results: The treatment group was superior to the control group in the comparison of clinical effects between both groups ITT: Z=-1.96, P=0.041; PP: Z=-2.01, P=0.039; BODE index and CAT scales of the treatment group lowered significantly(P<0.05). Conclusion: KeChuanNing capsules could effectively decrease BODE index and CAT scales of COPD patients, and improve quality of life and curative effects of the patients, and no obvious toxicity and adverse reaction is found.

相似文献/References:

[1]陈进凡,李萍,董晓梅,等.骨科手术患者自体血回输情况分析[J].西部中医药,2013,26(06):54.
 CHEN Jinfan,LI Ping,DONG Xiaomei,et al.On the Conditions of Autologous Blood Transfusion in Patients with Orthopedic Operation[J].Western Journal of Traditional Chinese Medicine,2013,26(03):54.
[2]赵宇冰,林丽明.老年慢性阻塞性肺疾病患者缓解期的社区康复治疗[J].西部中医药,2012,25(08):59.
 ZHAO Yu-bing,LIN Li-ming.Community Rehabilitation Therapy for Senile Patients with COPD at Remission Stage[J].Western Journal of Traditional Chinese Medicine,2012,25(03):59.
[3]李英,王晓素,姜清宇,等.清下化瘀方治疗急性胰腺炎疗效评价[J].西部中医药,2014,27(07):30.
 LI Ying,WANG Xiaosu,JIANG Qingyu,et al.Therapeutic Evaluation of Treating Acute Pancreatitis by the Prescription of Clearing Lower Energizer and Removing Blood Stasis[J].Western Journal of Traditional Chinese Medicine,2014,27(03):30.
[4]王萍.慢性阻塞性肺病患者实施临床护理路径的疗效分析[J].西部中医药,2014,27(11):140.
[5]王 燕,孙凤英,倪 军.慢性阻塞性肺疾病患者非药物治疗依从性与生活质量相关性的研究[J].西部中医药,2015,28(03):89.
[6]郭晓燕,尹广超,陆城华,等.川芎平喘合剂对COPD患者血管内皮功能的调节作用[J].西部中医药,2015,28(05):1.
[7]王振伟,杨佩兰,沈丽,等.百部养肺煎膏治疗COPD稳定期患者的临床研究[J].西部中医药,2015,28(05):56.
[8]施巍,苟小军,王道才,等.刺络放血法治疗慢性阻塞性肺疾病急性加重期48例[J].西部中医药,2017,30(02):96.
 SHI Wei,GOU Xiaojun,WANG Daocai,et al.Blood-letting Therapy in Treating 48 Cases of Chronic Obstructive Pulmonary Disease at Acute Exacerbation Stage[J].Western Journal of Traditional Chinese Medicine,2017,30(03):96.
[9]韩敏娟,曹鹏鹏,胡建明,等.慢性阻塞性肺疾病不同表型与中医证型的相关性研究[J].西部中医药,2016,29(03):63.
 HAN Minjuan,CAO Pengpeng,HU Jianming,et al.Correlation Study between Clinical Phenotypes of Chronic Obstructive Pulmonary Disease and TCM Patterns[J].Western Journal of Traditional Chinese Medicine,2016,29(03):63.
[10]史素丽,尚秀娟△,曹凤英.老年慢性阻塞性肺疾病患者主观幸福度及影响因素分析[J].西部中医药,2016,29(01):93.
 SHI Suli,SHANG Xiujuan,CAO Fengying.Analysis of Influencing Factors and Subjective Happiness Index of Senile Patients with Chronic Obstructive Pulmonary Disease[J].Western Journal of Traditional Chinese Medicine,2016,29(03):93.

备注/Memo

备注/Memo:
*基金项目:甘肃省青年基金项目(编号1011FKCA095)。作者简介:张旭辉(1977—),男,硕士学位,主治医师。研究方向:呼吸系统疾病的中西医结合诊治。
更新日期/Last Update: 2016-03-15