[1]景慧玲,冯立霞,马晓红,等.消疕合剂治疗血热风燥型进行期寻常型银屑病36例[J].西部中医药,2017,30(08):79-81.
　JING Huiling,FENG Lixia,MA Xiaohong,et al.XiaoBi Mixture in Treating 36 Cases of Psoriasis Vulgaris of Blood-heat Wind-dryness Pattern at Active Stage[J].Western Journal of Traditional Chinese Medicine,2017,30(08):79-81.
点击复制

消疕合剂治疗血热风燥型进行期寻常型银屑病36例
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
30
期数:
2017年08期
页码:
79-81
栏目:
出版日期:
2017-08-15

文章信息/Info

Title:
XiaoBi Mixture in Treating 36 Cases of Psoriasis Vulgaris of Blood-heat Wind-dryness Pattern at Active Stage
文章编号:
1004-6852(2017)08-0079-03
作者:
景慧玲，冯立霞，马晓红，郑楠
西安市中医医院皮肤科，陕西 西安 710021
Author(s):
JING Huiling, FENG Lixia, MA Xiaohong, ZHENG Nan
Department of Dermatology,Xi′an Hospital of Traditional Chinese Medicine, Xi′an 710021, China
关键词:
消疕合剂; 寻常型银屑病; 肿瘤坏死因子α; 白介素8
Keywords:
XiaoBi mixture;  psoriasis vulgaris;  TNF-α;  IL-8
分类号:
R758.63
文献标志码:
B
摘要:
目的：观察消疕合剂治疗血热风燥型进行期寻常型银屑病的临床疗效。方法：将68例患者随机分为观察组(36例)、对照组(32例)，观察组服用消疕合剂，50 mL/次，2次/d；对照组服用消银颗粒，3.5 g/次，3次/d。2组均于连续治疗3个月后观察治疗后前外周血清中肿瘤坏死因子α(TNF-α)和白介素8(IL-8)水平的变化情况及临床疗效。结果：总有效率观察组为88.89%，对照组为62.50%，2组比较差异有统计学意义(P＜0.05)。血清TNF-α、IL-8水平2组治疗前后组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较，差异也有统计学意义(P＜0.05)。结论：消疕合剂治疗血热风燥型寻常型银屑病疗效显著，其作用机制可能与调节血清中TNF-α和IL-8的水平有关。
Abstract:
Objective: To observe clinical effects of XiaoBi mixture in treating psoriasis vulgaris (PV) of blood-heat wind-dryness pattern at active stage. Methods: All 68 patients were randomized into the observation group (36 cases) and the control group (32 cases), the observation group took XiaoBi mixture, 50 mL each time, twice each day; the control group orally took XiaoYin granules, 3.5 g each time, three times each day. The levels of TNF-α and IL-8 in peripheral blood, and clinical effects were observed before and after treating when both groups were treated for three months consecutively. Results: Total effective rate of the observation group was 88.89%, higher than 62.50% of the control group, and the difference showed statistical meaning(P＜0.05). The difference showed statistical meaning in the comparisons of the levels of TNF-α and IL-8 before and after treating within one group (P＜0.05). The difference had statistical meaning in the comparisons between both groups after treating (P＜0.05). Conclusion: XiaoBi mixture is effective in treating PV of blood-heat wind-dryness pattern at active stage, and the mechanism might be related to regulating the levels of TNF-α and IL-8 in the serum.

相似文献/References:

[1]王昱瑾,张瑞恒,郏春梅,等.寻常型银屑病的三联疗法治疗及护理干预流程[J].西部中医药,2016,29(03):123.
　WANG Yujin,ZHANG Ruiheng,JIA Chunmei,et al.Nursing Intervention Procedure and Treating the Patients with Psoriasis Vulgaris by Triple Therapy[J].Western Journal of Traditional Chinese Medicine,2016,29(08):123.
[2]马莉,黄咏梅,王萍.解毒凉血汤联合刺络放血对寻常型银屑病疗效及患者血清CRP和PCT水平的影响[J].西部中医药,2023,36(11):127.[doi:10.12174/j.issn.2096-9600.2023.11.29]
　MA Li,HUANG Yongmei,WANG Ping.Curative Effects of Jiedu Liangxue Tang Combined with Bloodletting in the Treatment of Psoriasis Vulgaris and Its Influence on the Levels of Serum CRP and PCT[J].Western Journal of Traditional Chinese Medicine,2023,36(08):127.[doi:10.12174/j.issn.2096-9600.2023.11.29]

备注/Memo

备注/Memo:
收稿日期：2017-02-25 *基金项目：陕西省自然科学基础研究计划面上项目(编号2015JM8438)；西安市卫生局2014卫生科研项目(编号J2014025)。 作者简介：景慧玲(1979—)，女，硕士学位，副主任医师。研究方向：皮肤病的诊治。
更新日期/Last Update: 2017-08-15