[1]李强,张永莉.奥曲肽联合柴胡承气汤治疗急性胰腺炎52例[J].西部中医药,2018,31(08):1-3.
　LI Qiang,ZHANG Yongli.Octreotide Combined with ChaiHu ChengQi Decoction in Treating 52 Cases of Acute Pancreatitis[J].Western Journal of Traditional Chinese Medicine,2018,31(08):1-3.
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奥曲肽联合柴胡承气汤治疗急性胰腺炎52例()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年08期
页码:
1-3
栏目:
出版日期:
2018-08-15

文章信息/Info

Title:
Octreotide Combined with ChaiHu ChengQi Decoction in Treating 52 Cases of Acute Pancreatitis
文章编号:
1004-6852(2018)08-0001-03
作者:
李强1，张永莉2
1 成都市中西医结合医院急诊科，四川 成都 610041； 2 成都第一骨科医院
Author(s):
LI Qiang1, ZHANG Yongli2
1 Emergency Department, Chengdu Integrated TCM&Western Medicine Hospital, Chengdu 610041, China; 2 Number One Orthopedics Hospital of Chengdu
关键词:
急性胰腺炎; 奥曲肽; 柴胡承气汤; 炎性因子
Keywords:
acute pancreatitis;  octreotide;  ChaiHu ChengQi decoction;  inflammatory factor
分类号:
R657.5+1
文献标志码:
A
摘要:
目的：观察奥曲肽联合柴胡承气汤治疗急性胰腺炎(AP)的临床疗效。方法：将104例AP患者随机分为观察组、对照组各52例，2组均给予常规内科综合治疗加奥曲肽静脉推注治疗，观察组在此基础上同时给予胃管内注入或口服柴胡承气汤，2组均连续治疗1周。观察比较2组上腹部压痛消失时间、腹痛症状消失时间、血淀粉酶恢复正常时间，2组治疗前后血清C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)、白细胞介素１β(IL-1β)及白细胞介素6(IL-6)表达水平及临床疗效。结果：总有效率观察组为96.15%，对照组为76.92%，2组比较差异有统计学意义(P＜0.05)。上腹部压痛消失时间、腹痛消失时间、血淀粉酶恢复正常时间2组比较，差异有统计学意义(P＜0.05)。IL-6、IL-1β、TNF-α及CRP表达水平治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较差异也有统计学意义(P＜0.05)。结论：奥曲肽联合柴胡承气汤治疗AP临床疗效显著。
Abstract:
Objective: To survey clinical effects of octreotide and ChaiHu ChengQi decoction in treating acute pancreatitis (AP). Methods: All 104 AP patients were randomized into the observation group and the control group, 52 cases each group, both groups accepted conventional comprehensive therapy of internal medicine and intravenous injection of octreotide continuously, the observation group were infused with ChaiHu ChengQi decoction by stomach tube or took the decoction orally, both groups were treated for one week continuously. Tenderness disappearing time at the upper abdomen, disappearing time of abdominal pain, the time of hemodlastase returning to normal were observed and compared, the levels of IL-6, IL-1β, TNF-α and CRP of both groups were observed before and after treating, as well as clinical effects. Results: Total effective rate of the observation group was 96.15%, higher than 76.92% of the control group, and the difference had statistical meaning (P＜0.05). The difference was statistically significant in the comparisons of tenderness disappearing time at the upper abdomen, disappearing time of abdominal pain, the time of hemodlastase returning to normal between both groups (P＜0.05). There was a significant difference in the comparisons of the levels of IL-6, IL-1β, TNF-α and CRP within two groups before and after treating (P＜0.05); the difference had statistical meaning in the comparison between both groups after treating (P＜0.05). Conclusion: Octreotide and ChaiHu ChengQi decoction are effective in treating AP notably.

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备注/Memo

备注/Memo:
收稿日期：2018-02-20 作者简介：李强(1981—)，男，硕士学位。研究方向：外科疾病的临床诊治。
更新日期/Last Update: 2018-08-15