[1]于凤英,王鹏善,李长英.中医自拟方治疗小儿过敏性紫癜48例临床观察[J].西部中医药,2018,31(08):90-92.
 YU Fengying,WANG Pengshan,LI Changying.Clinical Observation on Selfmade Herbal Prescription in Treating 48 Cases of Pediatric Henoch-schonlein Purpura[J].Western Journal of Traditional Chinese Medicine,2018,31(08):90-92.
点击复制

中医自拟方治疗小儿过敏性紫癜48例临床观察()
分享到:

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年08期
页码:
90-92
栏目:
报道·临证经验
出版日期:
2018-08-15

文章信息/Info

Title:
Clinical Observation on Selfmade Herbal Prescription in Treating 48 Cases of Pediatric Henoch-schonlein Purpura
文章编号:
1004-6852(2018)08-0090-03
作者:
于凤英王鹏善李长英
高台县中医医院,甘肃 高台 734300
Author(s):
YU Fengying, WANG Pengshan, LI Changying
Gaotai County TCM Hospital, Gaotai 734300, China
关键词:
小儿过敏性紫癜治疗临床疗效
Keywords:
pediatric henoch-schonlein Purpura treatment clinical effects
分类号:
R554+.6
文献标志码:
B
摘要:
目的:观察自拟方治疗小儿过敏性紫癜的临床疗效。方法:将96例患儿按照门诊号随机分为观察组和对照组,2组均给予避免过敏原,改变血管脆性、脱敏等常规治疗,观察组在此基础上给予自拟方加减治疗;5天为1个疗程,共治疗10天。采用《过敏性紫癜治疗指南》拟定疗效标准判定总有效率,治疗后第5、7、10天观察皮肤紫癜例数、各组在治疗后分别检测血清白介素12(IL-12)、白介素8(IL-8)含量。结果:治疗2个疗程以后观察组总有效率为93.75%,对照组为79.17%,2组相比差异有统计学意义(P<0.05);紫癜消退2组在第7、10天差异有统计学意义(P<0.05);治疗后IL-12含量差异有统计学意义(P<0.05),IL-8含量比较差异无统计学意义(P>0.05)。结论:加减自拟方治疗小儿过敏性紫癜具有较好的临床疗效,其机制可能与抑制IL-12分泌有关。
Abstract:
Objective: To investigate clinical effects of selfmade prescription in treating pediatric Henoch-schonlein purpura(HSP). Methods: All 96 patients were allocated to the observation group and the control group according to the outpatient No., both groups accepted routine treatment of avoiding sensitizin, improving fragility of blood vessels, antianaphylaxis and others, the observation group were given modified selfmade prescription based on routine treatment; five days were one course, for ten days. Total effective rate was assessed by the drafted standard of clinical effect in treatment guidelines for allergic purpura, the number of the cases of purpura were observed at the fifth, seventh and tenth day after treating, the contents of IL-12 and IL-8 in the children were detected after treating. Results: After two courses, total effective rate of the observation group was 93.75%, higher than 79.17% of the control group, and the difference was statistically significant (P<0.05); there were the significant differences in the comparisons of purpura disappearing time at the seventh day and tenth day; the difference was statistically significant in the comparisons of the contents of IL-12 after treating(P<0.05), and the difference had no statistical meaning in the comparisons of the contents of IL-8(P>0.05). Conclusion: Modified selfmade prescription could gain better clinical effects in treating pediatric HSP, which might be related to inhibiting the secretion of IL-12.

相似文献/References:

[1]马腾.透穴疗法联合神经生长因子穴位注射治疗小儿麻痹性斜视50例临床观察[J].西部中医药,2012,25(12):92.
 MA Teng.Clinical Observation on Point-to-point Therapy and Point Injection of Nerve Growth Factor for 50 Cases of Infant Paralytic Strabismus[J].Western Journal of Traditional Chinese Medicine,2012,25(08):92.
[2]林海鸿.银翘散治疗手足口病的临床观察[J].西部中医药,2013,26(06):64.
 LIN Haihong.Clinical Observation on YinQiaoSan in Treating Hand-foot-and-mouth Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(08):64.
[3]彭燕.中医辨证护理对小儿流行性腮腺炎临床疗效的影响[J].西部中医药,2013,26(08):122.
 PENG Yan.TCM Nursing for Children with Mumps[J].Western Journal of Traditional Chinese Medicine,2013,26(08):122.
[4]贡保吉.藏西医结合治疗小儿支气管肺炎50例疗效观察[J].西部中医药,2013,26(10):65.
 GONG Baoji.Observation on the Combination of Tibetan and Western Medicine in Treating 50 Cases of Bronchopneumonitis in Children[J].Western Journal of Traditional Chinese Medicine,2013,26(08):65.
[5]扈志银.射干麻黄汤化裁佐治小儿毛细支气管炎 35 例[J].西部中医药,2014,27(08):55.
[6]张学军.护理干预在小儿重症肺炎并发呼吸衰竭中的临床作用[J].西部中医药,2014,27(08):134.
[7]柳树英,杨志华,原睿,等.微生态制剂与肠道菌群平衡观在小儿腹泻中的应用[J].西部中医药,2014,27(12):94.
[8]兰昌梅,王明明△.小儿咳嗽从脾论治的研究进展[J].西部中医药,2015,28(02):135.
[9]任耀全,石宗珂,沈玉鹏.麻杏化瘀汤加减治疗肺炎喘嗽痰热闭肺型疗效观察[J].西部中医药,2015,28(05):103.
[10]张晓春,王媛媛,李志锋,等.壮医药线背穴点灸治疗小儿外感发热100例[J].西部中医药,2015,28(06):67.[doi:2015/6/16 0:00:00]

备注/Memo

备注/Memo:
收稿日期:2018-02-27 作者简介:于凤英(1967—),女,副主任医师。研究方向:儿科疾病的中医诊治。
更新日期/Last Update: 2018-08-15