[1]安青,吴燕波,李伟兵,等.补精解毒方联合化疗治疗老年中晚期非小细胞肺癌40例[J].西部中医药,2018,31(10):76-79.
 AN Qing,WU Yanbo,LI Weibing,et al.Essence-supplementing Detoxifying Prescription Combined with Chemotherapy in Treating 40 Senile Patients with Advanced Non Small-cell Lung Cancer[J].Western Journal of Traditional Chinese Medicine,2018,31(10):76-79.
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补精解毒方联合化疗治疗老年中晚期非小细胞肺癌40例()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年10期
页码:
76-79
栏目:
报道·衷中参西
出版日期:
2018-10-15

文章信息/Info

Title:
Essence-supplementing Detoxifying Prescription Combined with Chemotherapy in Treating 40 Senile Patients with Advanced Non Small-cell Lung Cancer
文章编号:
1004-6852(2018)10-0076-04
作者:
安青123吴燕波123李伟兵123包玉华123俞晨123
1 江苏省肿瘤医院,江苏 南京 210029; 2 江苏省肿瘤研究所; 3 南京医科大学附属肿瘤医院
Author(s):
AN Qing123 WU Yanbo123 LI Weibing123 BAO Yuhua123 YU Chen123
1 Jiangsu Provincial Cancer Hospital, Nanjing 210029, China; 2 Jiangsu Provincial Cancer Institute 3 Cancer Hospital Affiliated to Nanjing Medical University
关键词:
肺癌补精解毒方化疗中晚期老年人
Keywords:
lung cancer essence-supplementing detoxifying prescription chemotherapy advanced stage
分类号:
R734.2
文献标志码:
B
摘要:
目的:观察补精解毒方联合化疗治疗老年中晚期非小细胞肺癌临床疗效。方法:将80例患者随机分观察组和对照组,每组40例。对照组给予化疗,观察组在对照组治疗的基础上服用补精解毒方。观察2组患者的疾病控制率、临床获益率、体质量增加稳定率及治疗前后KPS评分提高率、毒副反应及化疗周期。结果:疾病控制率2组比较,差异无统计学意义(P>0.05)。临床获益率、体质量增加稳定率及KPS评分提高率观察组优于对照组(P<0.05),观察组副反应发生例数少于对照组平均化疗周期长于对照组。结论:补精解毒方联合化疗治疗中晚期非小细胞肺癌能改善患者生活质量,提高疾病控制率和临床获益率,且能够减轻化疗引起的不良反应,增强老年人对化疗的耐受性。
Abstract:
Objective: To observe clinical effects of essence-supplementing detoxifying prescription joined with chemotherapy in treating senile patients with advanced non small-cell lung cancer (NSCLC). Methods: Eighty patients were randomized into the observation group and the control group, 40 cases each group. The control group accepted chemotherapy, while the observation group took essence-supplementing detoxifying prescription on the foundation of the therapy the control group received. The indexes of chemotherapy cycle, toxic and side effects, KPS improvement rate before and after treating, body mass increase stabilization rate, clinical benefit rate and disease control rate of both groups were observed. Results: The difference had no statistical meaning in the comparisons of disease control rate between both groups(P>0.05). The observation group was superior to the control group in clinical benefit rates body mass increase stabilization rate and KPS scores after treating (P<0.05), the observation group was less than the control group in the number of the coser suffering adverse reactions,longer than the control group in overage chemollerapy cycle. Conclusion: Essence-supplementing detoxifying prescription joined with chemotherapy in treating senile patients with advanced NSCLC could improve quality of life, raise disease control rate and clinical benefit rate, the method could reduce adverse reaction caused by chemotherapy and enhance the elderly′s tolerance to chemotherapy.

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备注/Memo

备注/Memo:
收稿日期:2018-04-27 *基金项目:国家自然科学基金项目(编号81503528);江苏省中医药局科研项目(编号YB2017091). 作者简介:安青(1970—),男,硕士研究生导师,主任医师,教授。研究方向:中西医结合肿瘤临床及基础研究。
更新日期/Last Update: 2018-08-15