[1]赵银龙.益气扶正解毒散联合高效抗病毒逆转录疗法治疗HIV/AIDS患者50例[J].西部中医药,2020,33(04):112-114.[doi:10.12174/j.issn.1004-6852.2020.04.34]
　ZHAO Yinlong.Treating 50 HIV/AIDS Patients by Qi-invigorating Body Resistance-strengthening Detoxifying Powder and Highly Active Anti-retroviral Therapy[J].Western Journal of Traditional Chinese Medicine,2020,33(04):112-114.[doi:10.12174/j.issn.1004-6852.2020.04.34]
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益气扶正解毒散联合高效抗病毒逆转录疗法治疗HIV/AIDS患者50例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
33
期数:
2020年04期
页码:
112-114
栏目:
出版日期:
2020-04-15

文章信息/Info

Title:
Treating 50 HIV/AIDS Patients by Qi-invigorating Body Resistance-strengthening Detoxifying Powder and Highly Active Anti-retroviral Therapy
文章编号:
1004-6852(2020)04-0112-03
作者:
赵银龙
酒泉市肃州区疾病预防控制中心，甘肃 酒泉 735000
Author(s):
ZHAO Yinlong
Suzhou District Center for Disease Control and Prevention of Jiuquan, Jiuquan 735000, China
关键词:
艾滋病; 益气扶正解毒散; 抗病毒逆转录疗法; CD4+T细胞计数; 中医证候评分
Keywords:
HIV/AIDS;  Qi-invigorating body resistance-strengthening detoxifying powder;  HAART; CD4+T cell counting;  TCM syndrome score
分类号:
R512.91
DOI:
10.12174/j.issn.1004-6852.2020.04.34
文献标志码:
B
摘要:
目的：观察益气扶正解毒散联合高效抗病毒逆转录疗法（highly active anti-retroviral therapy，HAART）治疗艾滋病(Acquired immunodeficiency syndrome，AIDS)患者的临床疗效。方法：将100例患者随机分为观察组和对照组，每组50例，两组均采用HAART一线方案［齐多夫定(AZT)/替诺福韦(TDF)+拉米夫定(3TC)＋依非韦伦(EFV))/奈韦拉平(NVP)］方案治疗，观察组在对照组治疗的基础上服用益气扶正解毒散，每次10 g，每日2次，两组均以治疗3个月为1个疗程，共治疗4个疗程。比较两组治疗后临床疗效、CD4+T细胞计数、中医证候评分及毒副反应发生情况。结果：总有效率观察组为94.00%（47/50），对照组为66.00%（33/50），两组比较差异有统计学意义(P＜0.05)。CD4+T细胞计数治疗后两组均明显升高，两组治疗前后组内及治疗后组间比较，差异均有统计学意义(P＜0.05)；证候积分治疗后均明显降低，两组治疗前后组内及治疗后组间比较，差异均有统计学意义(P＜0.05)。毒副反应发生率观察组为10.00%（5/50），对照组为36.00（18/50），两组比较差异有统计学意义(P＜0.05)。结论：益气扶正解毒散联合抗病毒疗法治疗AIDS患者临床疗效显著。
Abstract:
Objective: To survey clinical effects of Qi-invigorating body resistance-strengthening detoxifying powder (QBDP) and highly active anti-retroviral therapy (HAART) in the treatment of HIV/AIDS. Methods: All 100 patients were randomized into the observation group and the control group, 50 cases each group. Both groups adopted HAART first-line approach (AZT/TDF+3TC+EFV/NVP), the observation group took QBDP, 10g every time, twice each day, three months were one course, both groups were treated for four courses. To compare curative effects, CD4+ T cell counting, TCM syndrome score and the incidences of toxic and adverse reaction between both groups after treating. Results: Total effective rate of the observation group was 94.00% (47/50), higher than 66.00% (33/50) of the control group, and the difference had statistical meaning (P＜0.05). CD4+T cell counting rose notably after treating in both groups, the difference showed statistical meaning within two groups before and after treating, and between both groups after treating (P＜0.05); syndrome scores reduced in both groups notably after treating, and the difference had statistical meaning within two groups before and after treating, and between both groups after treating (P＜0.05). The incidence of toxic and adverse reaction in the observation group was 10.00% (5/50), lower than 36.00% (18/50) of the control group, and the difference showed statistical meaning between both groups(P＜0.05). Conclusion: QBDP and HAART could obtain notable clinical effects in the treatment of HIV/AIDS patients.

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备注/Memo

备注/Memo:
收稿日期：2019-10-15作者简介：赵银龙(1971—)，男，副主任医师。研究方向：艾滋病的中医药防治。
更新日期/Last Update: 2020-04-15