[1]方杭.清镇安神方治疗肝阳上亢型慢性脑供血不足疗效观察[J].西部中医药,2020,33(07):97-100.[doi:10.12174/j.issn.1004-6852.2020.07.25]
 FANG Hang.Clinical Observation on Qingzhen Anshen Prescription in Treating Chronic Cerebral Circulation Insufficiency of Liver Yang Hyperactivity Pattern[J].Western Journal of Traditional Chinese Medicine,2020,33(07):97-100.[doi:10.12174/j.issn.1004-6852.2020.07.25]
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清镇安神方治疗肝阳上亢型慢性脑供血不足疗效观察
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《西部中医药》[ISSN:1006-6977/CN:61-1281/TN]

卷:
33
期数:
2020年07期
页码:
97-100
栏目:
报道·临证经验
出版日期:
2020-07-15

文章信息/Info

Title:
Clinical Observation on Qingzhen Anshen Prescription in Treating Chronic Cerebral Circulation Insufficiency of Liver Yang Hyperactivity Pattern
文章编号:
1004-6852(2020)07-0097-04
作者:
方杭
上海市第八人民医院中医科,上海 200235
Author(s):
FANG Hang
TCM Department, Shanghai City the Eighth People′s Hospital, Shanghai 200235, China
关键词:
脑供血不足慢性头痛失眠肝阳上亢中医药
Keywords:
cerebral circulation insufficiency chronic headache insomnia liver-Yang hyperactivity TCM
分类号:
R249
DOI:
10.12174/j.issn.1004-6852.2020.07.25
文献标志码:
B
摘要:
目的:观察清镇安神方治疗肝阳上亢型慢性脑供血不足(chronic cerebral circulation insufficiency,CCCI)的临床疗效。方法:将肝阳上亢型慢性脑供血不足患者83例按随机数字表法分为试验组42例与对照组41例,试验组使用清镇安神方治疗,对照组使用西比灵胶囊治疗,经颅多普勒监测两组患者治疗前后大脑中动脉(middle cerebral artery,MCA)、大脑前动脉(anterior cerebral artery,ACA)、颈内动脉(internal carotid artery,ICA)、椎动脉(vertebral artery,VA)、基底动脉(basilar artery,BA)的平均血流速度(mean velocity,Vm),同时观察中医证候积分变化情况。结果:试验组中医证候显愈率为81.0%(34/42),高于对照组的51.2%(21/41),两组比较差异有统计学意义( χ2=8.205,P=0.004);试验组在改善患者头痛、失眠症状方面优于对照组,试验组西医显愈率为73.8%(31/42),高于对照组的58.5%(24/41),两组患者比较差异有统计学意义( χ2=6.463,P=0.011);两组患者血流速度均较治疗前改善,试验组高流速型CCCI患者MCA、VA及BA均低于对照组(P<0.05)。结论:清镇安神方可明显改善肝阳上亢型慢性脑供血不足患者头痛、失眠症状,其机制可能与调节脑血管血流速度有关。
Abstract:
Objective: To observe clinical effects of Qingzhen Anshen prescription(QA) in the treatment of CCCI of liver-Yang hyperactivity pattern. Methods: All 83 patients were divided into 42 cases of the study group and 41 cases of the control group according to random number table method, the study group were treated by QA, and the control group used sibelium capsules, to monitor Vm of MCA, ACA, ICA, VA and BA of both groups by transcranial Doppler (TCD), and TCM syndrome scores. Results: The effective rate of TCM syndrome of the study group was 81.0% (34/42), higher than 51.2% (21/41) of the control group, and the difference had statistical meaning between both groups ( χ2=8.205, P=0.004), the study group was superior to the control group in improving headache and insomnia; the effective rate of Western medicine in the study group was 73.8%(31/42), higher than 58.5% (24/41) of the control group, and the difference showed statistical meaning ( χ2=6.463, P=0.011); blood flow velocity of both groups improved compared with before treating, high velocity patients of the study group were lower than these of the control group in MCA, VA and BA. Conclusion: QA could obviously improve headache, insomnia of the patients with CCCI, and the mechanism might be related to regulating cerebral blood flow velocity.

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备注/Memo

备注/Memo:
收稿日期:2019-10-22作者简介:方杭(1989—),女,硕士学位,医师。研究方向:老年病的诊治。
更新日期/Last Update: 2020-07-15