[1]李春英.调经消异汤对子宫内膜异位症术后患者的影响[J].西部中医药,2020,33(08):93-95.[doi:10.12174/j.issn.1004-6852.2020.08.24]
　LI Chunying.Effects of Period-regulating Endometriosis-eliminating Decoction on Patients After the Surgery of Endometriosis[J].Western Journal of Traditional Chinese Medicine,2020,33(08):93-95.[doi:10.12174/j.issn.1004-6852.2020.08.24]
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调经消异汤对子宫内膜异位症术后患者的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
33
期数:
2020年08期
页码:
93-95
栏目:
出版日期:
2020-08-15

文章信息/Info

Title:
Effects of Period-regulating Endometriosis-eliminating Decoction on Patients After the Surgery of Endometriosis
文章编号:
1004-6852(2020)08-0093-03
作者:
李春英
青海福利慈善医院，青海 西宁 810007
Author(s):
LI Chunying
Qinghai Welfare Charity Hospital, Xining 810007, China
关键词:
子宫内膜异位症; 调经消异汤; 腹腔镜; 性激素; 血清糖类抗原; 肿瘤坏死因子α
Keywords:
endometriosis;  period-regulating endometriosis-eliminating decoction;  laparoscopy;  sex hormone;  serum carbohydrate antigen;  TNF-α
分类号:
R711.71
DOI:
10.12174/j.issn.1004-6852.2020.08.24
文献标志码:
B
摘要:
目的：观察调经消异汤联合腹腔镜术治疗子宫内膜异位症(endometriosis，EMT)的临床疗效及对术后患者血清糖类抗原125和199（CA125、CA199）及肿瘤坏死因子α(tumor necrosis factor α，TNF-α)的影响。方法：将110例患者随机分为两组，每组55例。两组均行腹腔镜保守手术治疗，观察组同时服用调经消异汤治疗4个月经周期，观察两组治疗前后中医证候积分、CA125、CA199、TNF-α、黄体生成素(luteinizing hormone，LH)、卵泡刺激素(follicle stimulating hormone，FSH)、雌二醇(estradiol，E2)、疼痛评分和临床疗效。结果：观察组总有效率为90.91%(50/55)，对照组为78.18%(43/55)，两组比较差异有统计学意义(P＜0.05)。中医证候积分、疼痛评分两组治疗后均较治疗前有所下降(P＜0.05)，且观察组下降程度大于对照组(P＜0.05)。CA125、CA199、TNF-α、LH、FSH及E2两组治疗后均较治疗前有所下降(P＜0.05)，且观察组下降程度大于对照组(P＜0.05)。结论：调经消异汤联合腹腔镜术治疗EMT患者，临床疗效显著，能显著降低EMT患者中医证候积分，有效降低CA125、CA199及TNF-α含量。
Abstract:
Objective: To observe clinical effects of period-regulating endometriosis-eliminating decoction combined with laparoscopy in treating endometriosis (EMT) and its influence on serum CA125, CA199 and TNF-α. Methods: All 110 patients were randomized into two groups, 55 cases each group. Both groups were treated by laparoscopic conservative surgery, the observation group took period-regulating endometriosis-eliminating decoction for four menstrual cycles simultaneously, to observe TCM syndrome integrals, serum CA125, CA199, TNF-α, LH, FSH, E2, VAS and clinical effects before and after treating between both groups. Results: Total effective rate of the observation group was 90.91% (50/55), higher than 78.18% (43/55) of the control group, and the difference was statistically significant (P＜0.05). TCM syndrome integrals and VAS in both groups after treating reduced than before treating (P＜0.05), and the decrease of the observation group was greater than that of the control group (P＜0.05). CA125, CA199, TNF-α, LH, FSH and E2 in both groups after treating decreased compared with these before treating (P＜0.05), and the decrease of the observation group was greater than that of the control group (P＜0.05). Conclusion: Period-regulating endometriosis-eliminating decoction combined with laparoscopy could obtain notable clinical effects in treating EMT patients, notably lower TCM syndrome integrals of EMT patients, effectively reduce the contents of CA125, CA199 and TNF-α.

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备注/Memo

备注/Memo:
收稿日期：2019-08-30作者简介：李春英(1976—)，女，主治医师。研究方向：妇产科疾病的临床诊治。
更新日期/Last Update: 2020-08-15