[1]李福民,李丰林,蒋自乐,等.自制“活血通络膏”联合玻璃酸钠治疗风寒湿痹型膝痹病（膝骨关节炎）的临床疗效[J].西部中医药,2021,34(07):108-111.[doi:10.12174/j.issn.2096-9600.2021.07.28]
　LI Fumin,LI Fenglin,JIANG Zile,et al.Clinical Effects of Selfmade “Blood-activating Collaterals-dredging Ointment” and Sodium Hyaluronate in Treating Knee Osteoarthritis of Wind-cold-damp Arthralgia Pattern[J].Western Journal of Traditional Chinese Medicine,2021,34(07):108-111.[doi:10.12174/j.issn.2096-9600.2021.07.28]
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自制“活血通络膏”联合玻璃酸钠治疗风寒湿痹型膝痹病（膝骨关节炎）的临床疗效
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年07期
页码:
108-111
栏目:
衷中参西
出版日期:
2021-07-15

文章信息/Info

Title:
Clinical Effects of Selfmade “Blood-activating Collaterals-dredging Ointment” and Sodium Hyaluronate in Treating Knee Osteoarthritis of Wind-cold-damp Arthralgia Pattern
作者:
李福民1, 李丰林2, 蒋自乐1, 坎旭1
1.张掖市中医医院，甘肃 张掖 734000
2.民乐县中医医院
Author(s):
LI Fumin1, LI Fenglin2, JIANG Zile1, KAN Xu1
1.Zhangye City Hospital of TCM, Zhangye 734000, China
2.Minle County Hospital of TCM
关键词:
膝骨关节炎; 膝痹病; 风寒湿痹型; 活血通络膏; 玻璃酸钠; 临床观察
Keywords:
knee osteoarthritis; knee arthralgia; wind-cold-damp arthralgia pattern; blood-activating collaterals-dredging ointment; sodium hyaluronate; clinical observation
分类号:
R493
DOI:
10.12174/j.issn.2096-9600.2021.07.28
摘要:
目的观察自制“活血通络膏”外用联合膝关节腔内注射玻璃酸钠治疗风寒湿痹型膝骨关节炎的临床疗效和安全性。 方法将膝骨关节炎患者60例按就诊先后顺序随机分为观察组、对照组各30例。观察组行自制“活血通络膏”联合膝关节腔内注射玻璃酸钠治疗，对照组行膝关节腔内注射玻璃酸钠治疗，两组均连续治疗5周为1个疗程。观察治疗前后两组患者VAS评分、WOMAC骨关节炎指数评分、中医证候积分变化情况及临床疗效与不良反应发生情况。 结果总有效率观察组高于对照组（P＜O.05），VAS评分、WOMAC骨关节炎指数评分、中医证候积分观察组低于对照组（P＜O.05）；ALT、AST、BUN及SCr两组比较差异无统计学意义（P＞O.05）。 结论“活血通络膏”外敷与膝关节腔内注射玻璃酸钠能通络止痛，祛风除湿，温里散寒，提高风寒湿痹型膝痹病的临床疗效，且安全有效。
Abstract:
ObjectiveTo observe clinical effects and the safety of selfmade “blood-activating collaterals-dredging ointment” for external application combined with intra articular injection of sodium hyaluronate in treating knee osteoarthritis of wind-cold-damp arthralgia pattern. MethodsSixty patients were randomized into the observation group and the control group according to the visiting order, 30 cases each group. The observation group were treated by selfmade “blood-activating collaterals-dredging ointment” for external application combined with intra articular injection of sodium hyaluronate, and the cotnrol group by intra articular injection of sodium hyaluronate, both groups were treated for five consecutive weeks as one course of the treatment. To observe VAS scores, WOMAC, TCM syndrome integrals, clinical effects and the incidence of adverse reaction before and after treating between both groups. ResultsTotal effective rate of the observation group was higher than that of the control group (P<0.05). The observation group was lower than the control group in VAS scores, WOMAS and TCM syndrome integrals (P<0.05); the difference had no statistical meaning in ALT, AST, BUN and SCr between both groups (P>0.05). ConclusionSelfmade “blood-activating collaterals-dredging ointment” for external application combined with intra articular injection of sodium hyaluronate in treating knee osteoarthritis of wind-cold-damp arthralgia pattern could unblock collaterals and relieve pain, dispel wind and remove dampness, warm the interior and dispel cold, which is safe and effective.

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备注/Memo

备注/Memo:
李福民（1967—），男，主任医师。研究方向：脊柱创伤。
更新日期/Last Update: 2021-07-15