[1]周琪,毛夏丽,魏同,等.基于肠道微生态从脾论治再生障碍性贫血研究进展[J].西部中医药,2022,35(03):141-144.[doi:10.12174/j.issn.2096-9600.2022.03.33]
　ZHOU Qi,MAO Xiali,WEI Tong,et al.Research Progress on Treating Aplastic Anaemia from Spleen Based on Intestinal Microecology[J].Western Journal of Traditional Chinese Medicine,2022,35(03):141-144.[doi:10.12174/j.issn.2096-9600.2022.03.33]
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基于肠道微生态从脾论治再生障碍性贫血研究进展
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年03期
页码:
141-144
栏目:
研究进展
出版日期:
2022-03-15

文章信息/Info

Title:
Research Progress on Treating Aplastic Anaemia from Spleen Based on Intestinal Microecology
作者:
周琪, 毛夏丽, 魏同, 席亚明
兰州大学/兰州大学第一医院，甘肃 兰州 730000
Author(s):
ZHOU Qi, MAO Xiali, WEI Tong, XI Yaming
Lanzhou University/The First Hospital of Lanzhou University, Lanzhou 730000, China
关键词:
再生障碍性贫血; 肠道菌群; 肠道微生态; 脾虚; 健脾补肾; 中医药; 综述
Keywords:
aplastic anaemia; intestinal flora; intestinal microecology; spleen deficiency; invigorating spleen and tonifying kidney; TCM; review
分类号:
R552
DOI:
10.12174/j.issn.2096-9600.2022.03.33
文献标志码:
A
摘要:
从肠道微生态与中医脾的联系、再生障碍性贫血（aplastic anaemia，AA）与肠道微生物相关性及AA从脾论治的源流及治法治则3方面入手综述基于肠道微生态从脾论治AA的研究进展，指出AA属慢性疾病中的虚劳性疾病，核心病因病机为脾肾亏虚，治疗以健脾补肾法贯穿始终；而“脾”具有的运化抗邪功能与肠道菌群对机体的代谢和免疫功能相似，此可能为中医脾功能的生物学基础；AA的发生发展与肠道菌群紊乱密切相关，将中医发病机制与现代肠道微生态理论相结合探究调节肠道微生态的中药复方制剂与单味药物的应用可为治疗AA提供新思路。
Abstract:
Research progress of treating aplastic anaemia (AA) from spleen based on intestinal microecology is reviewed from three aspects: the correlations between intestinal microecology and spleen in TCM, the relation between AA and intestinal flora, the source of treatment of AA from spleen, therapeutic methods and principles. It is pointed out that AA belongs to asthenic disease in chronic diseases, the core etiology and pathogenesis is deficiency of spleen and kidney, and the method of strengthening spleen and tonifying kidney runs throughout the treatment; in the theory of TCM, the spleen has the function of transporting and transforming and fighting against the pathogenic factors, similar to the effects of intestinal flora on metabolism and immune function, which may serve as the biological basis of splenic function of TCM; the incidence and development of AA is closely related to intestinal flora disorder, by combining TCM mechanism with modern intestinal microecology theory, herbal compound prescription and single herb for regulating intestinal microecology are investigated to provide the new thinking for the treatment of AA.

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备注/Memo

备注/Memo:
周琪（1994—），女，在读博士研究生。研究方向：内科血液病学。
更新日期/Last Update: 2022-06-24