[1]芮敏劼,嵇辉,杨增敏,等.应用FRAX工具预测原发性骨质疏松症患者发生骨质疏松性骨折风险的回顾性研究[J].西部中医药,2025,38(06):52-55.[doi:10.12174/j.issn.2096-9600.2025.06.11]
　RUI Minjie,JI Hui,YANG Zengmin,et al.Prediction of the Risk of Osteoporotic Fractures in Patients with Primary Osteoporosis Using FRAX Tools: A Retrospective Study[J].Western Journal of Traditional Chinese Medicine,2025,38(06):52-55.[doi:10.12174/j.issn.2096-9600.2025.06.11]
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应用FRAX工具预测原发性骨质疏松症患者发生骨质疏松性骨折风险的回顾性研究()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年06期
页码:
52-55
栏目:
调查分析
出版日期:
2025-06-15

文章信息/Info

Title:
Prediction of the Risk of Osteoporotic Fractures in Patients with Primary Osteoporosis Using FRAX Tools: A Retrospective Study
作者:
芮敏劼1, 嵇辉1, 杨增敏1, 佟兴业1, 马勇1,2
1.南京中医药大学附属南京市中西医结合医院，江苏 南京 210014
2.南京中医药大学，江苏 南京 210023
Author(s):
RUI Minjie1, JI Hui1, YANG Zengmin1, TONG Xingye1, MA Yong1,2
关键词:
原发性骨质疏松症; 骨质疏松性骨折风险; FRAX工具; 回顾性研究
Keywords:
primary osteoporosis; the risk of osteoporotic fractures; FRAX tools; retrospective study
分类号:
R274.1
DOI:
10.12174/j.issn.2096-9600.2025.06.11
文献标志码:
B
摘要:
目的通过FRAX软件系统评估原发性骨质疏松症（primary osteoporosis，POP）患者发生骨质疏松性骨折的风险，探讨不同中医证型、不同营养状况、既往骨折次数、有无股骨颈骨密度值与骨质疏松性骨折风险的相关性。 方法选取POP患者155例，依照中医证型、营养状态、既往骨折次数及有无骨密度值进行分组，统计发生骨质疏松性骨折的风险并进行分析。 结果肝肾阴虚型患者全身主要部位发生骨质疏松性骨折风险最高（P＜0.05）；肝肾阴虚型患者髋部发生骨质疏松性骨折风险高于脾肾阳虚型（P＜0.05）；有无骨密度值对于FRAX系统评估质疏松性骨折风险影响不大（P＞0.05）；有多次骨折史患者发生骨质疏松性骨折的风险高于其他组（P＜0.05）；不同营养状态患者发生骨质疏松性骨折的风险差异无统计学意义（P＞0.05）。 结论中医证型及既往骨折次数对于FRAX工具评估骨质疏松性骨折发生风险有明确影响；在无股骨颈骨密度具体数值时，询问其他风险因素后带入FRAX系统得出的骨折风险具有一定临床指导意义。
Abstract:
ObjectiveTo systematically evaluate the risk of osteoporotic fractures in patients with primary osteoporosis using FRAX tools, so as to discuss the correlations of different TCM patterns, different nutritional states, number of previous fractures, whether there are bone mineral density values of femoral neck, with the risk of osteoporotic fractures. MethodsAll 155 patients were chosen, and grouped according to TCM patterns, nutritional states, number of previous fractures, whether there are bone mineral density values of femoral neck, the risks of osteoporotic fractures were statistically counted and analyzed. ResultsThe risk of osteoporotic fracture is the highest in the main body parts of the patients of Yin deficiency of liver and kidney pattern (P<0.05); the risks of osteoporotic fractures were higher in the hip of the patients of Yin deficiency of liver and kidney pattern than the ones of Yang deficiency of liver and kidney pattern (P<0.05); whether there are bone mineral density values had little influence on the assessment of the risk with FRAX tool (P>0.05); the risks of osteoporotic fractures were higher in patients with history of multiple fractures than the ones in other groups (P<0.05); the difference had no statistical meaning in the risks of osteoporotic fractures between patients with different nutritional states (P>0.05). ConclusionTCM patterns and number of previous fractures present influence on evaluating the risk of osteoporotic fractures with FRAX tool, when there is no specific values of bone mineral density of fermoral neck, the risk of bone fractures assessed with FRAX tools after investigating other risk factors has certain clinical guiding significance.

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[1]曾昭洋,胡文斌,魏学玲,等.中老年人原发性骨质疏松症与中医体质类型的Logistic回归分析[J].西部中医药,2018,31(02):66.
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备注/Memo

备注/Memo:
芮敏劼（1991—），男，硕士学位，主治医师。研究方向：骨科疾病的中西医结合诊治。国家中医药管理局监测统计中心项目（YGZXKT2024122）；江苏省中医药学会科研项目（CYTF2024023）；江苏省省级中医重点专科（苏中医医政函〔2023〕5号）；南京市名中医工作室（宁卫中医〔2023〕9号）。
更新日期/Last Update: 2025-06-15